We all want to protect our pets from fleas and ticks, and our
homes from flea infestations.
There are many great
products out there right now, like Advantix and Frontline Plus, that makes doing so
easy, like spot-on that kill adult fleas and ticks and stop the
growth of new fleas. But what if a medication no longer seems
to be working well or you want extra protection for your pet—is
it safe to add a second flea and tick medication?
Every pet is different. The right product(s) for one pet might
not be right for another pet, which is why having guidelines is
important in making the best choices
for your best friend. Some pets might do well with Advantage Multi for cats and others
with Nexgard. Below are some
tips to help you protect your pets.
How to Find the Right Combination
Always read product labels, particularly the drug interaction
sections, if you intend to combine products, and check with
your vet before combining products.
Products that only treat fleas are generally safe to combine
with products that only treat ticks. But similar to how some
people can have different reactions to combinations of
medication—pets can react differently to combinations of
medications. Your pet might have special medical conditions
that only a veterinarian would know. Again, consult your
veterinarian before combining medications.
Combinations to Know: Oral Flea Treatments
Either Capstar or Comfortis can be combined
individually with a variety of other flea and tick medications
including one of the following: K9
Advantix II, Frontline Plus for
Dogs, Advantage II for
Dogs, Revolution for dogs,
Pet Armor for Dogs, Advantage Multi, Frontline Top Spot for
Dogs, Sentinel, or Farnam Bio Spot for Dogs. Capstar will knock out
a flea infestation quickly and is over the counter. Comfortis
requires a prescription and works to kill adult fleas for a
It’s not usually recommended to use more than one oral flea
medication at the same time. However, Comfortis and Capstar can
be combined. Another exception is Sentinel, which doesn’t kill
adult fleas, so it can be combined individually with either
Comfortis or Capstar.
Combinations to Know: Flea Collars
Some flea collars, like Preventic, are generally safe to
combine individually with one of the following: Frontline Plus,
Revolution, Pet Armor, Frontline Top Spot or Farnam Bio Spot,
K9 Advantix II, Advantage II,
Trifexis, Interceptor, Certifect, or Advantage
Multi. When used in conjunction with one of the above
medications, Preventic collars have been shown to be effective
for flea and tick prevention, particularly tick prevention. A
good time to use a collar like Preventic with your normal
preventative is if you're going for a deep woods hike with your
dog. You can remove the collar after the hike! Talk to your vet
before combining a Seresto flea
collar with any other medications.
Combinations to Know: Heartworm Medication
If you’re concerned about combining heartworm medication with
flea and tick products, Heartgard is a good choice, as it
doesn’t target fleas or ticks. This means that it can usually
be safely combined with other flea and tick medications.
However, Heartgard is not safe to combine with a flea and tick
medication if that second medication also contains heartworm
Combinations Not to Use
Here are some examples of common medications that should never
be combined: Frontline Plus should not be combined with
Advantage II; Advantage Multi should not be combined with
Revolution; with the exception of Capstar or the Preventic
collar, Advantage Multi should not be combined other
medications. Frontline products should not be used in
conjunction with Advantage or Advantix products.
Your pet shouldn’t receive a flea bath if they have recently
been introduced to another flea or tick treatment (for example,
if your pet was treated with a spot on in the past month). If
your pet is given a flea bath, they shouldn’t receive another
medication for a few days after—Capstar is a more flexible,
reliable alternative to flea baths.
Flea and tick treatments that are applied to the surrounding
environment—either outdoors or in your home, usually won't
conflict with medications given directly to your pet. Just try
to be mindful of where you're aiming the treatment (don’t spray
Some Final Tips
Using more than the recommended dosage of any individual
medication is never advisable. This is not limited to
prescription flea and tick medications. In fact,
over-the-counter medications can present greater risks when
more than the recommended quantity is given to your pet. In
particularly bad flea or tick infestations, certain products
recommended for monthly use might be used every three weeks
under the advice and supervision of your vet.
Aside from any of the above exceptions, it is not recommended
to combine medications that are designed to target the same
problems (in essence, “doubling up” on certain types of
products). For example, it is not safe to use more than one
spot-on flea and tick medication during the time that the
product is still active more than one oral flea and tick
medication, or more than one product that contains heartworm
medication at the same time. Consult your veterinarian if
you’re not sure about a medication choice.
Will I Overmedicate My Pet if I Mix Flea Meds?
We can't say it enough. Read and follow the package
instructions for any and all medications you give your pet.
Even over-the-counter products can be dangerous if misused or
combined with the wrong products (the label should mention
potential drug interactions), so read those labels and always
ask your vet if you have any questions.
Don’t Play Pharmacist
When it comes to flea and tick medicine, pet owners are often
looking for a quick fix. In reality, it can take three months or more to
completely rid your pet of a flea’s full life cycle.
(Capstar is a good quick
way to knock out an adult infestation should one occur, but it
won't deal with the complete flea life cycle). Don’t let human
impatience harm your pet. Allow the medication to completely
work its way into your pet’s system before sounding the alarm.
Whatever you do, don’t take dosage matters into your own hands.
Overmedicating your animal or not following weight /dosage
guidelines can really harm your pet.
If your pet is battling a serious case of flea infestation consider adding
Capstar or a flea collar.
Collars will help kick start the healing process by moving
fleas away from the head and neck and down to the rear of the
body--not a total fix but it should provide some
relief. Read this article to
learn more about what flea and tick products can be
combined. And again, always check with your vet if you have
questions about which products to use and combine for your pet.
How PetPlus Can Help
When it comes to protecting your dog from fleas and ticks,
PetPlus is the best way to provide them
with the medications they need. Everything from topicals like
K9 Advantix II and Frontline Plus to collars like Seresto is right at your fingertips,
and with savings, you are going to love -- some as high as
More Flea and Tick Control Advice
The Flea Life Cycle
How to Kill Fleas in the Yard
Flea and Tick Season: When to Use What
How Do Flea Collars
Oral Flea Control: Flea
Pills For Dogs And Cats