At a Glance
Trifexis kills fleas, prevents heartworm, and treats and controls intestinal parasites
Trifexis is a once monthly beef flavored chewable tablet
No isolation from other pets necessary when using Trifexis
This product requires a prescription.
An alternative to Trifexis is Sentinel
Our regular price:
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Spinosad, Milbemycin oxime
Side Effects and Warnings
Adverse reactions to Trifexis include vomiting, itching, ear redness, skin redness and inflammation, loss of appetite, diarrhea, and lethargy. Use Trifexis with caution in dogs with epilepsy. Puppies less than 14 weeks old may excessively vomit. Consult your veterinarian in regard to pregnant or lactating dogs before giving them Trifexis. If your dog experiences any listed effects, contact your veterinarian immediately. Trifexis is not meant for any Collie breed dogs.
Do not use ivermectin in addition to Trifexis. Consult your veterinarian regarding the addition of any other medication, supplement, or vitamins.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
Elanco Animal Health
5-10 lbs., 6 pack
10.1-20 lbs., 6 pack
20.1-40 lbs., 6 pack
40.1-60 lbs., 6 pack
60.1-120 lbs., 6 pack
Store Trifexis at room temperature.
Dog must be tested by a veterinarian, and rid of worms, prior to taking Trifexis. Administer Trifexis orally according to prescribed dosage, based on weight.
Rated 4.5 out of 5 by 125
Rated 5 out of 5 by Lisacakes Great Product
I love Trifexis for my dog. It kills fleas and it's eggs very quickly. It also protects him from heartworms, hook worms; etc. All in one chewable tablet once a month. Super convenient. I highly recommend Trifexis for its efficient effectiveness, ease of use and convenience. Additionally, the discounted price at Pet care RX is fantastic. Thank you guys for a great product at a great price.
May 2, 2016
Rated 5 out of 5 by PoodleNews Vet Recommended
Vet recommended - best price found through your service.
The old product seemed to become ineffective so this was recommended by Vet. Seems to be working fine.
May 1, 2016
Rated 4 out of 5 by LoPo tad expensive
One pill seems to do the trick. Just a bit pricey, even from PetCareRx.
March 27, 2016
Rated 5 out of 5 by Chuck61 No complaints....
This product was recommended by my veterinarian, and has worked effectively for a long time.
March 21, 2016
Rated 5 out of 5 by Stel This is the best product for fleas that I have found for our dogs.
No other product has been as effective for our dogs to keep fleas off. It also has the added bonus of protecting them from heart worm too so it is a great value!
March 7, 2016
Rated 5 out of 5
by BubbaRon Trifexis has been great for our Doberman!!!
Our vet recommended Trifexis for our young female Doberman and she has been on it for over 3 years now. It works great for us and is very easy to use - just one pill, once a month - PetCareRX is very easy and economical to use, they even keep track of when you need to re-supply!!
March 6, 2016
Rated 5 out of 5 by davis5253 This product is amazing
We have used this for years and our dogs have NEVER had any fleas or heartworms. We live in middle TN in the woods, so we have TONS of fleas and ticks. It is well worth the money.
February 8, 2016
Rated 5 out of 5 by MickyK Lives up to the good reviews
Our dog won't chew it, but she loves the treat she gets afterward! Sometimes it makes her lethargic for a day, but we have never seen a flea.
January 21, 2016
Elanco Animal Health
Flea & Tick
Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.
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based on 125