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At a Glance
Trifexis’ two active ingredients work to protect dog parasite infestation.
Active ingredient spinosad paralyzes and kills the adult fleas (and other insects) once it bites the skin.
Active ingredient milbemycin oxime is a parasiticide that protects against three intestinal parasites (i.e., roundworms, hookworms, and whipworms) and is a 100% effective heartworm disease preventative.
One chewable tablet per month is administered orally to work for the next 30 days.

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Rated 4.5 out of 5 by 185 reviewers.

  • Excellent Product
    Helps keep our little girl happy and healthy. will continue to take care of her as needed. by on 08/12/2020
  • As prescribed
    It appears to be working. No worms, no fleas. And just as importantly, no upset bellies from the dogs after they take it. by on 07/03/2020
  • Best Place for Pet supplies
    Great pricing and the customer service is always outstanding. by on 06/17/2020
  • Dogs love this "special treat"!
    Happy my dogs like this once a month medication! by on 06/17/2020
  • It continues to work
    Ongoing protection against worms, fleas (and even ticks!) So far, neither of my canines (Australian Shepherd and Pom/Chihuahua mix) have had any adverse reactions. by on 05/01/2020
  • Best oral flea/tick for dogs
    Been using Trifexis on both of my dogs and they work great! by on 04/27/2020
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