K9 Advantix II for Dogs
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At a Glance
Three active ingredients kill a variety of insects and prevent infestations.
Kill fleas and ticks within the first 12 hours after application.
Once-a-month application kills and prevents future infestations for 30 days.

K9 Advantix II for Dogs

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At a Glance
Three active ingredients kill a variety of insects and prevent infestations.
Kill fleas and ticks within the first 12 hours after application.
Once-a-month application kills and prevents future infestations for 30 days.

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Ultimate Guide to K9 Advantix II for Dogs

Meet Dog's Most Trusted Flea and Tick Repellent: K9 Advantix II for Dogs!

K9 Advantix II for Dogs is the veterinarian-approved dog medication with three strong active ingredients to protect your dogs from fleas, ticks, mosquito, and lice. K9 Advantix II for Dogs is a once-a-month spot-on topical treatment that remains effective for the next four weeks after application.

The K9 Advantix II for Dogs Guarantee: External parasites and other insects don't stand a chance against your lovable (and prepared) pup!

How does K9 Advantix II for Dogs work?

K9 Advantix II for Dogs is made up of strong three active ingredients to make it an effective once-a-month flea, tick, and mosquito treatment to prevent, repel, and kill pesky parasites: Imidacloprid, Permethrin, and Pyriproxyfen.

Imidacloprid is the world's most used insecticide. Once the blood-sucking flea bites your dog, K9 Advantix II for Dogs attacks their central nervous system causing paralysis and its imminent death. Permethrin is the same but for ticks on contact. Pyriproxyfen (IGR) regulates the growth of flea larvae and at any stage of the flea life cycle.

How is K9 Advantix II for Dogs administered?

K9 Advantix II for Dogs is a topical formula that uses the spot-on treatment approach that is effective for the next four weeks after treatment. Proper spot-on treatment is packaged in individual doses of liquid and is applied by pouring the liquid onto the back of your pet.

Apply K9 Advantix II for Dogs 3 to 4 spots along the dog's spine from between the shoulder blades to the base of the tail. Use one-third to one-fourth of the tubes' contents in each spot applied on the dog's skin. See the chart below to know the specific dosage for your dog:

Weight Dosage
10 lbs. and under0.4 mL (Green)
11 lbs. - 20 lbs.1.0 mL (Teal)
21 lbs. - 55 lbs. 2.5 mL (Red*)
55 lbs. +4.0 mL (Blue*)
*Use several spots for a larger animal to avoid irritation.

Though the solution is waterproof, wait for a few hours to pet or bathe your dog. Once the solution is dry, You don't need to reapply after bathing or swimming.

Which dogs should not use K9 Advantix II for Dogs?

Pregnant and lactating dogs. Puppies under 7 weeks old. Elderly dogs or those who are in a debilitated state. Be aware if your dog is allergic to any of the active ingredients. Lastly, keep out of reach of children or cats. The active ingredient permethrin is indigestible to cats.

What are the potential side effects of which you should be aware?

After the application of K9 Advantix II for Dogs, your furry best friend commonly experiences itching, burning, or numbness of their skin. If pain persists after a few hours, call your vet. If irritation persists after 3 days, call your vet.

Frequently Asked Questions
  1. What is the difference between K9 Advantix II large dogs vs. small dogs?

    All formulas have the same percentages of the active ingredients (8.8% Imidacloprid, 44% Permethrin, 0.44% Pyriproxyfen, and 46.76% other ingredients), but small dogs, medium dog, large dogs, and extra-large dogs require a different dosage depending on the dog's weight (see chart above).

  2. What are the K9 Advantix reviews?

    K9 Advantix II for Dogs reviews gives the solution 4.5+ stars out of 5. Most reviewers say that they are long time users of this excellent product that ensure that there ain't no bugs on their furry best friend. Reach out to your vet if having any concerns or questions about your dog's use of K9 Advantix II for Dogs.

  3. How long does it take for K9 Advantix II to work on fleas and ticks?

    K9 Advantix II for Dogs kills fleas and ticks within 12 hours after application. In terms of new fleas, these parasites that newly bite your dog dies within 2 hours. K9 Advantix II for Dogs kills fleas and prevents infestations throughout the following four weeks.

  4. Is K9 Advantix II for puppies?

    K9 Advantix II for Dogs can be administered to puppies that are at least 7 weeks old.

  5. What is K9 Advantix II for Dog's active ingredients?

    Imidacloprid is the world's most used insecticide. Once the blood-sucking flea bites your dog, it attacks their central nervous system causing paralysis and its imminent death. Permethrin is the same but for ticks on contact. Pyriproxyfen is an insect growth regulator that regulates the growth of all fleas at any stage of the life cycle.

  6. What are the K9 Advantix side effects?

    Irritation is very common after the application. However, call your vet if the irritation persists for longer than 3 days, and if the pain lasts for longer than a few hours.

  7. Is K9 Advantix II for Dogs used for cats?

    No. K9 Advantix and K9 Advantix II for Dogs is for dogs only. Cats cannot digest the active ingredient Permethrin (i.e., treatment for ticks). They should even be kept away from K9 Advantix-treated dogs for 24 hours.

    However, with the two other active ingredients (e.g., Imidacloprid and Pyriproxyfen), Advantage II for Cats is a formula for once-a-month topical flea prevention and treatment for cats that effectively breaks the flea life cycle to prevent future infestations. The cat must be a minimum of 8 weeks old and a weight of 9 pounds.

Concluding Thoughts

The most important thing that you should know about K9 Advantix II for Dogs is its power to kill fleas, ticks, mosquitos, and lice on contact and prevent future infestations for 30 days after one application.

DISCLAIMER: Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition.

  • Elanco Animal Health Brand
  • Flea & Tick Pharmacy
  • Elanco Animal Health Manufacturer
  • Spot On/Topical Application
  • Dog Pet Type

Do You Need a Prescription for K9 Advantix II?
Answer

Prescriptions are a mandate when there is an administration of medicine to the drugs. These drugs are often controlled by the FDA. The absence of any medicine that will be ingested by the pets makes them be out of the purview of the FDA. Therefore the prescriptions are not needed for the superficial treatment of fleas ticks and mosquitoes by the use of K9 Advantix II for Dogs. However, an important aspect to note is if the ticks infestation is too high, it often can lead to tick fever. During such situations, you must contact your petโ€™s vet immediately to administer the right medications along with this tick and flea treatment.

Is K9 Advantix II Safe for Dogs?
Answer

K9 Advantix II for Dogs is completely safe to use for your pets at home. You can start using the product among dogs that are over 7 weeks of age. Although it is a non-harmful drug that kills fleas ticks, special care must be taken while administering the drug to the younger pups as well as to the aging dogs that are at a weakening stage due to their age. Till forty-eight hours of administration of K9 Advantix II for Dogs, do not give your pets a bath or shampoo them. This will help increase the efficacy of the product and help you achieve the maximum coverage and help get rid of the majority of the infestations.

What Is the Safest Flea and Tick Treatment for Dogs?
Answer

The use of chemical agents to treat fleas or ticks that can cause harm to pets is not recommended. Such usage can often be harmful to your pet and can lead to toxicity. If you are to opt for one that has chemicals to treat the flea or tick control as an additional aid with your existing ones, be sure to use the less toxic ones. A good idea can be to check the details of the ingredients on the product label which gives all the necessary information. As per Natural Resources Defense Council or NRDC, in case there is a need for additional treatment for the infestations by the fleas and ticks with the use of chemical products, s-methoprene or pyriproxyfen are recommended. The reason being these are less toxic ingredients. You can check the label for such products too, as often it is found that manufacturers club other harmful or toxic ingredients with these.

How Long After Applying K9 Advantix Can I Touch My Dog?
Answer

The action of K9 Advantix II for Dogs stays for forty-eight hours. So touching your furry friends can happen only after this period. In ideal scenarios, most manufacturers often recommend touching the pets only after the product applied to their body dries out. You should wait till that time when such a period passes. You can also keep track of the pests that fall off your pet post administration of K9 Advantix II for Dogs.

What Happens if Dog Licks Advantix?
Answer

Often it happens that the pets can lick the areas that have been applied with the K9 Advantix II for Dogs or they can scratch those areas with their feet and lick them later. In such cases, there are chances that your pet can start to salivate due to the bitter taste of the product, foam can also form in the mouth. They can also start to vomit or nauseate because of the same.

How Often Should I Use Advantix on My Dog?
Answer

K9 Advantix II remains effective for four weeks after each application. However, if your dog has severe infections they may need the administration of K9 Advantix in more than one scenario in the same month. But make sure not to apply this more than once every seven days. Once you see that the fleas are controlled, you can return to the normal monthly dosage.

Is Advantix Toxic to Dogs?
Answer

K9 Advantix II for Dogs has been supported by the United States Environment Protection Agency. There are no cases of toxicity that have been reported against the usage of K9 Advantix II for Dogs. This is the reason that the veterinarians recommend the use of this shampoo to get rid of the ticks or flea infestation among the dogs. Pet owners also trust this product for the treatment of their pets and keep them away from any harmful chemicals that are mostly found in the commercially available products in the market that help serve the same purpose, either in the form of ingestible or superficial applicators.

Can I use K9 Advantix II on my elderly dog?
Answer

The answer to this relative and you should consult with your veterinarian before using any medication on your elderly dog, including K9 Advantix II. This is because older dogs may have health issues or take medications that could interact with K9 Advantix II, potentially causing harmful side effects. Additionally, K9 Advantix II is designed for dogs of a certain weight range and age, so it's vital to ensure that your dog falls within the appropriate parameters for the medication.

Is K9 Advantix II waterproof?
Answer

Yes, K9 Advantix II is waterproof once it has been applied and absorbed into the skin. This means that your dog can be bathed or swim after the product has had a chance to dry, typically within 24 hours of application. However, it's important to note that excessive bathing or swimming may decrease the product's effectiveness, so it's generally recommended to avoid bathing your dog more than once a week and to wait at least 48 hours after application before allowing your dog to swim or bathe.

How long does K9 Advantix II last?
Answer

K9 Advantix II provides protection against fleas, ticks, and other parasites for up to one month (30 days) after application. However, the period of time the product is effective might vary based on factors like your dog's activity level, exposure to water or bathing, and the severity of the flea and tick infestation in your area.

Can I use K9 Advantix II on my dog with sensitive skin?
Answer

K9 Advantix II is not recommended for use on dogs with sensitive skin. While it is generally considered safe and effective for most dogs, dogs with sensitive skin may be more prone to developing skin irritation or other adverse reactions to the medication. Your veterinarian can evaluate your dog's skin health and recommend a flea and tick medication that is less likely to cause irritation or other adverse reactions.

How does K9 Advantix II compare to other flea and tick treatments?
Answer

K9 Advantix II has the benefit of being waterproof, allowing dogs to swim or take a bath without having the drug lose its potency. Even pups as young as 7 weeks old can utilize it without concern. Also, K9 Advantix II provides broad-spectrum defense against a variety of parasites, including mosquitoes and biting flies, in comparison to other flea and tick medications, which may be crucial if you reside in a region where these pests are common. For dogs with sensitive skin or those who are prone to skin irritations or other unfavorable reactions to flea and tick treatments, it might not be the ideal option.

Can I use K9 Advantix II on dogs with medical conditions?
Answer

Yes, however before taking K9 Advantix II or any other flea and tick medicine, it's essential to speak with your veterinarian. Some medical conditions or medications may interact with K9 Advantix II or other flea and tick medications, potentially causing adverse reactions or reducing the effectiveness of the medication.

Can K9 Advantix II be used with other medications?
Answer

It is important to consult with your veterinarian before using K9 Advantix II with other medications, as some drugs may interact with imidacloprid and permethrin, the active ingredients in K9 Advantix II. Certain medications may increase the risk of adverse reactions or reduce the effectiveness of the medication, so you should disclose all medications and supplements that your dog is currently taking to your veterinarian. Additionally, K9 Advantix II should not be used on dogs that are currently taking other flea and tick medications without first consulting with a veterinarian.

Is K9 Advantix II effective against all types of fleas?
Answer

K9 Advantix II is effective against several species of fleas, including the common cat flea (Ctenocephalides felis) and the dog flea (Ctenocephalides canis). These fleas are the most common species found on dogs and are responsible for causing itching, scratching, and other skin irritations. K9 Advantix II is designed to kill fleas on contact, as well as to repel new fleas from infesting your dog for up to 4 weeks after application.

Does K9 Advantix II work to prevent mosquitoes?
Answer

Yes, in addition to fleas, ticks, and other parasites, K9 Advantix II is effective against mosquitoes. Imidacloprid and permethrin, the two active components in K9 Advantix II, combine to both repel and kill mosquitoes on contact.

Does K9 Advantix II eradicate heartworms?
Answer

K9 Advantix II is not an effective treatment for heartworms. K9 Advantix II is made to guard against fleas, ticks, mosquitoes, and other biting flies, but it does not destroy heartworms. Heartworm illness is brought on by a parasitic worm that is spread by mosquitoes.

How do I dispose of empty K9 Advantix II tubes?
Answer

To dispose of empty K9 Advantix II tubes, empty the contents of the tube onto your dog's skin as directed, and allow it to dry completely before recapping it. Place the capped tube in a plastic bag, seal the bag, and discard it in your household trash. Do not reuse empty K9 Advantix II tubes, and do not pour unused products down the drain or toilet.

Advantix is comprised of some of the most effective flea and tick repellants on the market - Imidacloprid, Permethrin, and Pyripoxyfen.

KEEP AWAY FROM CATS. Cats are unable to process the key ingredients in Advantix. They should be distanced from the dog for up to 24 hours after application. Some dogs may experience a burning, itching, tingling, or numbness of the skin after application.ย 

May cause a slight irritation on the point of contact, but this usually subsides within a few hours. If pain persists, contact a vet. Oral contact may cause salivation. If K9 Advantix gets into you or your dogs eyes, flush with water immediately.

This sensation usually subsides within 3 days, however if symptoms persist, consult your veterinarian.

K9 Advantix is an effective, once a month flea & tick treatment that uses three types of medication (imidacloprid, permethrin, pyriproxyfen) to kill, prevent the growth of, and repel these pesky parasites. Imidacloprid is the most widely used insecticide in the world, attacking the central nervous system of fleas, while having little to no effect on mammals. Permethrin works in much the same way as imidacloprid, but against ticks, killing them on contact. Pyriproxyfen is an insect growth regulator (IGR), which means that it prevents flea larvae from further developing into adults, thereby stopping the flea life cycle in its tracks.

K9 Advantix is for dogs only. K9 Advantix should not be used in dogs that are in a debilitated state, elderly, pregnant, nursing, or under 7 weeks of age. Dogs that are taking other flea and tick medication should not be taking K9 Advantix, and dogs with a known allergy to any of the ingredients in K9 Advantix should not take this treatment. Cats should NEVER be given K9 Advantix, as they are unable to process permethrin. Contact to this medication by cats can be serious and even fatal. Cats should be kept away from dogs taking K9 Advantix up to 24 hours after being treated.

The proper way to apply K9 Advantix is to take the applicator tube out of its packaging and remove the cap, holding upright so as to not spill the contents. Depending on your dogโ€™s weight, apply the solution in either 3 or 4 spots along their spine, between the shoulder blades and the base of their tail. Make sure to apply directly to the skin by ruffling their fur. Place a third to a quarter of the tubes contents in each of the spots of application, being careful to avoid dripping. Allow a few hours for the solution to dry before petting or bathing. The solution is waterproof, so once dry, there is no need to reapply if your dog decides to go swimming or is in need of a bath.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Have your dog stand to ease the application process and evenly distribute the contents of one tube on 2-3 spots along their back, between their shoulders and the base of their tail. Part their hair so that skin is visible and gently squeeze the solution onto the skin. Make sure there is no excess dripping, and allow 1 hour to dry.

Store Advantix in a cool, dry place. Keep out of reach of children or cats.

K9 Advantix II for Dogs is manufactured by Elanco Animal Health
Option UPC/SKU
Green, 10 lbs. and under, 4 Month Supply 724089203489
Teal, 11-20 lbs., 4 Month Supply 724089203724
Red, 21-55 lbs., 4 Month Supply 724089203991
Blue, 55 lbs. and over, 4 Month Supply 724089204103
Blue, 55 lbs. and over, 6 Month Supply 724089204295
Green, 10 lbs. and under, 6 Month Supply 724089203649
Red, 21-55 lbs., 6 Month Supply 724089204028
Teal, 11-20 lbs., 6 Month Supply 724089203809

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