Capstar Flea Killer for Dogs
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At a Glance
Capstar is the ultimate solution for your dogโ€™s persistent flea problem.
Its active ingredient, nitenpyram, that starts killing fleas in the first 30 minutes after application.
Its efficacy shows itself after 4 hours and continues to demonstrate its effects for 1-2 days after one dosage.
Capstar Flea Killer for Dogs is recommended by veterinarians and doesnโ€™t require a prescription.

Capstar Flea Killer for Dogs

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At a Glance
Capstar is the ultimate solution for your dogโ€™s persistent flea problem.
Its active ingredient, nitenpyram, that starts killing fleas in the first 30 minutes after application.
Its efficacy shows itself after 4 hours and continues to demonstrate its effects for 1-2 days after one dosage.
Capstar Flea Killer for Dogs is recommended by veterinarians and doesnโ€™t require a prescription.

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Elanco Animal Health Logo

Ultimate Guide to Capstar Flea Killer for Dogs

Meet the Relentless Flea Killer: Capstar!

Capstar Flea Killer for Dogs is an oral tablet that is easy to administer and offers quick relief for all pets. It is famously known to start killing adult fleas and their infestations in just 30 minutes is a veterinarian-approved potent dog flea killer medication that protects your dog from the irritating flea infestations. Capstar continues to work for the next 24-48 hours after administering it.

How does Capstar work?

Capstar is a medication with one active ingredient and generic name Nitenpyram. Nitenpyram is a systemic insecticide used to treat adult flea infestations and is effective in treating fly larvae aka maggots. As said before, the fleas start dying and falling off the dog (or cat) after 30 minutes and the effects can last up to 24-48 hours after administered.

How is Capstar administered?

Capstar is an oral tablet that can be administered once a day or weekly or whenever your dog needs it to kill a flea infestation, whether adult fleas or fly larvae. The Capstar tablet can be placed in the dog's mouth or eaten with the dog's food.

Which dogs should be distanced from Capstar?

Those who are allergic to the active ingredient Nitenpyram. Puppies that are less than 2 lbs or younger than 4 weeks old. It is safe to administer Capstar to pregnant and nursing dogs, but still, stay cautious. Most likely, dogs with liver or kidney disease shouldn't use Capstar.

What are the potential side effects of which you should be aware?

You don't need to be concerned about other medications taken with nitenpyram, but be transparent with your veterinarian about any medications that your dog is taking. Your pup doesn't require specific monitoring after Capstar is administered.

Capstar's rare and uncommon adverse reactions reported are vomiting, increased or decreased activity, lethargy, itching, decreased appetite, and diarrhea.

Frequently Asked Questions

Does Capstar Kill Flea Eggs?

Capstar doesn't work on fleas in the egg state. It requires the larvae to mature into adult fleas before the medication can start working. That's because the active ingredient, nitenpyram, only targets adult fleas. However, it offers great results on adult flea infestations in dogs and cats.

Once you administer Capstar Flea Killer, the nitenpyram present in it starts working within the first 30 minutes and continues to work for the next 24 to 48 hours. It's extremely effective for treating persistent flea infestations in adult dogs and cats. It even works on fly larvae (maggots).

Does Capstar Kill Fleas?

Absolutely. Capstar is a powerful veterinarian-recommended over-the-counter medication for treating adult flea infestations in dogs. Its active ingredient, nitenpyram, is a potent insecticide that kills flea and fly larvae without harming your pet. It starts working within 30 minutes of administering the medication and reaches its peak efficacy within four hours.

Nitenpyram from the tablet is quickly absorbed into your dog's bloodstream after you orally administer the medicine. Whenever a flea bites them, it ingests the blood containing nitenpyram. That's what causes fleas to die within 4 to 5 hours of administering Capstar Flea Killer to your dog.

Does Capstar Kill Flea Larvae?

While Capstar is one of the most effective flea control pills for dogs and cats, it doesn't work on flea larvae. But once the larvae reach the adult stage, Capstar offers great results. Also, it's easy to administer and doesn't cause any major side effects.

That means you can administer the tablet to your pet once a day or weekly without worrying about any adverse reactions. Once your dog ingests the tablet, its active ingredient starts getting absorbed into the bloodstream, and kills any fleas that bite your dog.

How Long Will Capstar Kill Fleas?

Once it's been administered, Capstar continues to kill fleas for the next 24 to 48 hours. Its maximum efficacy is reached within 4 hours of administering the drug. Around this time, you'll notice fleas (and/or maggots) falling off your pet's body.

Depending on the intensity of the infestation, you can administer a second dosage 1-2 days after the first one. Capstar flea tablets are safe for consumption once a day or on a weekly basis.

What Is in Capstar That Kills Fleas?

Capstar uses only one active ingredient with the generic name nitenpyram. It's a powerful systemic insecticide that makes Capstar one of the most effective flea pills on the market. While nitenpyram is known to instantly kill fleas and maggots, it doesn't cause any adverse reactions in dogs and cats.

You can administer the medication orally or mix it in your dog's food. Once your dog ingests the medicine, nitenpyram is quickly absorbed into their blood. This, in turn, kills fleas whenever they bite your dog's skin.

How Long Does It Take for Capstar to Kill Fleas?

Capstar Flea Killer starts working roughly 30 minutes after it's administered. That's the reason you'll notice ticks falling off your pet's body soon after they take the pill. The tablet becomes most active 4 hours after it's been administered. It continues to work for the next 24 to 48 hours as well.

Does Capstar Kill All Fleas?

Yes. Capstar is formulated to treat adult flea infestations in dogs and cats. It even works on fly larvae. While the medication doesn't work on flea eggs and larvae, it offers excellent results for adult fleas. You can even administer Capstar on young puppies who are more than 4 weeks of age and weigh more than 2 pounds.

Does Capstar Kill Fleas and Ticks?

Capstar kills adult fleas within 30 minutes of being administered. It's a great instant solution for treating heavy flea infestations in dogs and cats. Also, it works on fly larvae. But Capstar isn't effective in killing flea eggs, flea larvae, and ticks. If you're looking for a combined treatment for flea and tick infestation, make sure you consult your veterinarian.

Does Capstar Kill Fleas on Nursing Puppies?

Capstar isn't recommended for nursing puppies who are less than four weeks old. For puppies above the age of four weeks, you can administer Capstar if they weigh more than 2 lbs. It is, however, a good idea to consult your vet before using Capstar as a flea treatment for puppies. They'll help you determine the right dosage and frequency for administering the tablet.

Is Capstar a Monthly Flea Prevention Treatment?

When it comes to preventing flea infestations, Capstar may not offer the best results. That's because it doesn't kill flea eggs and larvae. However, it does provide instant relief in case of adult flea infestations. Also, you can administer it once a day or weekly depending on your dog's needs. If you're looking for a more permanent and preventative treatment, it's best to talk to your vet.

Concluding Thoughts

The most important thing that you should know about Capstar is that it is the ultimate solution for your dog's persistent flea problem with nitenpyram that starts killing fleas in the first 30 minutes after application. Its efficacy shows itself after 4 hours and continues to demonstrate its effects for 1-2 days after one dosage.

DISCLAIMER: Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition.

  • Elanco Animal Health Brand
  • Flea & Tick Pharmacy
  • Capstar Pharmacy Brands
  • Protection Wellness Philosophy
  • Flea Allergy Dermatitis Skin & Coat Health
  • Ivermectin Sensitivity Allergies
  • Giant Breed Pet Size
  • Elanco Animal Health Manufacturer
  • X-Small Breed Pet Size
  • Small Breed Pet Size
  • Medium Breed Pet Size
  • Large Breed Pet Size
  • Dog Pet Type

What Is Capstar?
Answer

Capstar is a brand name for a kind of flea treatment for dogs and cats. The primary component of Capstar is nitenpyram, a pesticide that kills fleas by interfering with their neurological systems.

What Is the Capstar Dosage for Dogs?
Answer

Capstar is available in two dosages: 11.4 mg tablets for dogs weighing between 2 and 25 pounds and 57 mg tablets for dogs weighing between 25.1 and 125 pounds. The medication is administered based on the veterinarianโ€™s prescription.

Should I Bathe My Dog After Capstar?
Answer

It is safe to bathe your dog after administering Capstar, but it is generally recommended to wait at least 6 hours before bathing your dog. This is because the medication needs time to work and fully kill off the fleas. Additionally, bathing your dog too soon after administering Capstar could potentially wash off some of the medication and reduce its effectiveness. If you decide to bathe your dog after Capstar, it is important to use a gentle, dog-specific shampoo and to thoroughly rinse your dog to remove all the shampoo and medication.

Will Fleas Leave Your Dog Without Treatment?
Answer

Fleas will rarely go untreated on your dog. Fleas are incredibly tenacious and adaptive parasites that may live and breed in several settings, including on the skin and fur of your dog. Hence, medication is vital for killing and removing fleas from your dogโ€™s system.

How Safe Is Capstar for Large Dogs?
Answer

Capstar for large dogs is generally considered a safe medication when used as directed. It is an oral medication rapidly absorbed into your dog's bloodstream, and it works by interfering with the flea's nervous system, causing it to die. Capstar for puppies is not recommended for pups under 4 weeks old. Capstar is also not advised for dogs that are pregnant or nursing.

Can I Use Frontline and Capstar at the Same Time?
Answer

Yes, it is generally safe to use Frontline and Capstar together. Frontline is a topical flea and ticks preventative medication applied to your dog's skin, while Capstar is an oral medication that works quickly to kill adult fleas. Using both medicines can be an effective way to quickly kill fleas and prevent infestations. However, it is important to follow the dosage instructions provided by your veterinarian or on the product labels and to only use medications specifically formulated for dogs.

What Are the Problems With Capstar?
Answer

Capstar is a medication designed to quickly kill adult fleas on dogs, but there are some potential problems to consider. It has a short duration of action, lasting only 24 hours, so it must be administered daily or used with another flea-preventative medication. It only kills adult fleas and has no residual effect, so additional flea control measures may be necessary to control a flea infestation. Capstar can also cause side effects such as vomiting, diarrhea, lethargy, and itching, although these are usually mild and resolve independently. Lastly, it does not protect against parasites such as ticks, mites, or heartworms.

Can You Mix Capstar With Water?
Answer

No, you should not. Capstar is an oral medication designed to be swallowed whole by your dog. It should not be mixed with water or other liquids before administration, which can affect the medication's effectiveness. Capstar tablets are designed to dissolve quickly in your dog's mouth and are flavored to make them more palatable. If your dog has difficulty swallowing the tablet, you can try hiding it in food or administering it directly into the back of the throat.

Can Humans Take Capstar?
Answer

No, Capstar is a medication specifically formulated for dogs and cats, and humans should not take it. The active Capstar ingredient, nitenpyram, is not approved for human use and can cause adverse effects. If you have fleas in your home or on your pets and are concerned about flea bites, there are other medications and treatments available for humans, such as topical creams and antihistamines, that can help relieve symptoms.

Does Capstar Prevent Future Fleas?
Answer

No, Capstar does not prevent future flea infestations. Capstar is an oral medication designed to quickly kill adult fleas on dogs and cats but not prevent them. Capstar for cats or dogs begins working within 30 minutes of administration and continues to kill adult fleas for up to 24 hours.

How Long Does Capstar Stay In My Dogโ€™s System?
Answer

Capstar is a medication designed to be rapidly absorbed and eliminated from your dog's system. Nitenpyram is metabolized and excreted from the body relatively quickly. Capstar has a short duration of action, lasting up to 24 hours, and it is usually eliminated from the body within 24-48 hours.

Nitenpyram

Overviewย 

The medication Nitenpyram is in use orally and helps to act rapidly against the fleas and is a neonicotinoid responsible for adulticide.ย 


Special Precautions

The use of Nitenpyram is not advisable for dogs that have allergies. Also, pets that are under two pounds of body weight or have an age of fewer than 4 weeks should not have the medication. The pets that are in the age bracket of four to eight weeks old should be cautiously given the medication. The pets that are thin or debilitated should not have the medication. The pregnant and nursing pets should have a cautious recommendation of the drug.ย 


Uses

Nitenpyram helps to ensure law toxicity and quick absorption for cats and dogs. This aspect helps to achieve great results with a single dose of the medication to eradicate the flea population at a rapid pace. Past studies indicate that fleas can get eradicated within 30 minutes of giving the medication. After around eight hours of medication, there is a reduction of around 98 to 99% of the reduction in most animals. The short life of the drug helps to clear out its residues from the body via urine quickly. Therefore, there will be no bioaccumulation of the product in your petโ€™s body.


Mechanism of Action

This antiseptic drug has had phenomenal results in the treatment of fleas and showcases fast action for the killing of the fleas in their adult state. The inhibition of postsynaptic nicotinic acetylcholine receptors leads to the removal of sodium iron influx.


The complete absorption of Nitenpyram happens within a span of 8 to 9 hours in most animals. The apocalyptic effect of the drug on the fleas leads to their higher mortality rate under any condition. Your pet will get complete flea control and the drug will also move out of the system via urination quickly.


Known Drug Interactions

There are no visible interactions of Nitenpyram that are spotted to date. However, there are many studies that are being carried out to understand the impact of the drug on any other medicine. You can inform your veterinarian about any medication that your pet is currently taking.


Brand/Generic Equivalents

Capstar

Capstar Flea Killer is associated most commonly with itching soon after taken. However, the itching is caused by the fleas as they die, not Capstar, and is temporary. In rare cases, cats react with hyperactivity, panting, vocalization, and excessive grooming.

Capstar Flea Killer has no known adverse drug interactions and may be used with other products including antibiotics, corticosteroids, de-worming medications, heartworm preventives, shampoos, vaccines, and other flea products.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Capstar Flea Killer may be administered orally, daily to weekly, mixed into food if necessary. See directions on packaging for proper dosage.

Store at room temperature.

Capstar Flea Killer for Dogs is manufactured by Elanco Animal Health
Option UPC/SKU
2-25 lbs., 6 pack 073091033370
Over 25 lbs, 6 pack 727804366681

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Customer Reviews

Rating Summary 92 review(s)
5 stars
75
4 stars
6
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5
2 stars
4
1 star
2
5 / 5
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A
I like it
VERIFIED PURCHASER

It does what itโ€™s supposed to

Alex recommends this item.
Was this review helpful? 1 0

A
good Pills
VERIFIED PURCHASER

Good pill to get rid of all fleas on dogs it will not kill the fleas that go on them after 30 min

Alix recommends this item.
Was this review helpful? 1 0

L
It works!
VERIFIED PURCHASER

I was very surprised when I tried Capstar. I didn't know what to expect and thought, here goes another thing that won't work..It worked! It's continued working since I started my Gigi on it. I couldn't be happier and neither can she. She was in agony scratching and was covered in fleas every time I bathed her. I'm so happy I've found a solution for her & our problem! Thank you, Capstar!

Lourdes recommends this item.
Was this review helpful? 3 0

M
Works Great!
VERIFIED PURCHASER

I have nine indoor only cats that got fleas?? Don't know how. I used Capstar flea killer and it works. I would crush up the pill and put it in their food. The pill is tiny so when you crush it, the cats don't see a thing. It only kills the adult fleas for 24 hours. You need to use something else to kill the babies.

Maureen G recommends this item.
Was this review helpful? 3 0

K
Capstar Flea Killer
VERIFIED PURCHASER

Works within hours & works GREAT!

Keri recommends this item.
Was this review helpful? 3 0

K
Flea pill

The product was good and I liked it. My dog took it easily and I noticed a great difference within hours.

Kat0306 recommends this item.
Was this review helpful? 5 0

J
Capstar Fizzle
VERIFIED PURCHASER

We used this product a few months ago and it worked fine. Either this shipment was bad or the fleas gathered a very fast tolerance. The fleas were back within a week.

Jannie recommends this item.
Was this review helpful? 5 0

B
This product is easy to use .
VERIFIED PURCHASER

The Capstar product works very well . It does not seem to effect the pet . Instructions are easy to follow . I would recommend this product to everyone .

BuffCat1 recommends this item.
Was this review helpful? 2 0

T
Great features
VERIFIED PURCHASER

If your dog comes in contact with a flea infestation , cap star will rid them from your dog in 24 hours

Terry68 recommends this item.
Was this review helpful? 2 0

G
instant results
VERIFIED PURCHASER

i have 9 indoor cats only 4 go outside for a few hours daily, with all the rain we have seen recently, fleas were a major problem, with 9 cats, veterianary bills get outrageous, I love Capstar!!!!!!I shared the tablets between the cats which had been scratching, running like trying to get away from the biting, within 20 minutes they started scratching less, relaxing and finally resting. As they relaxed more, I would check them, I couldn't believe what I saw, DEAD FLEAS around their bodies on thier blankets. I am so glad I ordered Capstar, and so are my cats.

grannyof3 recommends this item.
Was this review helpful? 3 0

B
Doesn't work
VERIFIED PURCHASER

Gave my four cats more than ten doses to no avail.

barth recommends this item.
Was this review helpful? 3 0

F
This product is great for one time use but need more for a feral cat.
VERIFIED PURCHASER

I was looking for a product for fleas and ticks, even though this product was good for initial treatment still not what I needed and what I need is not offered in feline form. I do thank you for offering this as an option.

felinelove recommends this item.
Was this review helpful? 2 0

Y
Quick results.
VERIFIED PURCHASER

Nice to be able to kill the fleas in about a day. Just wish it also killed the eggs too. They say you can use it daily if needed, but I don't want to do that. Also can get expensive that way.

ydonner recommends this item.
Was this review helpful? 2 0

M
This product works like a charm
VERIFIED PURCHASER

It is the best flea medicine I have found, works quickly and gives your pet immediate relief. You can give the med every 24 hours but I find it will work 48 hrs.

maggie55 recommends this item.
Was this review helpful? 2 0

J
Flea Free
VERIFIED PURCHASER

Easy and effective flea protection. My dog eat's it like it's a treat!

Jupsie recommends this item.
Was this review helpful? 3 0

D
Works fine
VERIFIED PURCHASER

Gave my dogs their pill and they took the pill easily one need a piece of cheese, have had no problems with fleas.

ddoer recommends this item.
Was this review helpful? 3 0

T
Best Flea Product I have found.
VERIFIED PURCHASER

I just couldn't seem to get rid of the fleas on my "boys". I do not want to keep using pesticides every month and from what I have read Capstar is much less harmful. It also works wonderfully. Love it! It's a star with me!

TribSamRennysMom recommends this item.
Was this review helpful? 1 0

T
Good Product
VERIFIED PURCHASER

The pill works great by itself. Try and catch on sale......

Texasfair recommends this item.
Was this review helpful? 0 0

C
Excellent product for killing fleas
VERIFIED PURCHASER

Gave it to my cat and within 20 minutes fleas were dropping and dying. Unbelievable! Then gave a 2nd dose 2 days later to kill off any eggs that might have hatched same results. Definitely buy this product if your dog or cat is infested with fleas.

Connie1660 recommends this item.
Was this review helpful? 0 0

P
It works so quickly
VERIFIED PURCHASER

I love this product. It is safe to use and very effective.

petpoodle recommends this item.
Was this review helpful? 0 0

M
Excellent, just wished price better
VERIFIED PURCHASER

Capstar works great especially on fleas. I only use it once a month with good results. Dog likes its flavor. Only drawback is price but product is excellent.

Meme57 recommends this item.
Was this review helpful? 0 0

J
Lightning Fast! Super Effective!
VERIFIED PURCHASER

I really wasn't sure if this would be as quick as the product description claimed, but decided I'd try it anyways. We have four active indoor/outdoor dogs and I was amazed how quickly this product worked. I slipped the pills into a treat for each of our four indoor/outdoor dogs and within minutes, 1 minutes, I could see results. I found it was effective for about a month at a time for our two outdoor dogs and 2 or more months at a time for our two indoor dogs.

JenniferHasFourDoggies recommends this item.
Was this review helpful? 0 0

A
Product is easy to use
VERIFIED PURCHASER

I do not think is very effective on controlling fleas

Angie10 recommends this item.
Was this review helpful? 0 0

B
Capstar Flea Killer not working either!

I bought this to see if would work on my dogs as all the ones that I've been using topically haven't been working. Well this one didn't work either, still have fleas on all my dogs. Guess I will have to try the expensive one. These fleas have become immune to everything else.

bluidgenie recommends this item.
Was this review helpful? 0 0

M
easy to use when you need it
VERIFIED PURCHASER

first time I used and it did good . Just a bad year for fleas and they were difficult to control. used this in between times when needed to keep down on fleas.Nothing is really working anymore.. not even K9 advantix this year and you can't fumigate the whole county and all the neighbors .... I hate that Program was taken off market. It worked and its a shame the Vets controlled that. Fleas should be a priority not vets getting richer.

mejachan recommends this item.
Was this review helpful? 1 0

C
This product is good as far as I can tell.
VERIFIED PURCHASER

The only thing I have a slight problem with is the price. I have two dogs and this product can get a little costly for me. Other than that, I have used Capstar before and I really thought it worked.

Cindy247 recommends this item.
Was this review helpful? 0 0

S
MONTH LONG FLEA KILLER PILL
VERIFIED PURCHASER

ORIGINALLY PRESCRIBED BY VET AS PART OF TOTAL FLEA PLAN. PetCareRx IS ABOUT 50% CHEAPER FOR EXACT SAME PRODUCT! KILLS ONLY ADULT BITING FLEAS, BUT WHEN USED IN COMBINATION WITH FRONTLINE II WHICH KILLS ALL STAGES OF FLEAS, EGGS, LARVAE, AND ADULT, AND BEDDING AREA, PLUS AREA SPRAY, DOGS ARE FLEA FREE.CAPSTAR IS CRITICAL PART OF PROGRAM TO KILL THE ADULT BITING FLEAS ON YOU DOG.

SPSCA recommends this item.
Was this review helpful? 1 0

C
Capstar works great
VERIFIED PURCHASER

Capstar works great for killing full grown fleas. Wish there was another tablet form for eggs without a prescription. Cannot use liquid product; in the past oil from product ruined our leather couches.

Cats2 recommends this item.
Was this review helpful? 0 0

T
Best option for killing fleas!
VERIFIED PURCHASER

Whether you have a problem with a few fleas or what seems like an infestation, this product does the trick quick. Absolutely worth it. So much easier and effective than any powders, liquids, or shampoos.

TO111 recommends this item.
Was this review helpful? 0 0

R
This product works very well.
VERIFIED PURCHASER

It really easy to give to my dogs. However, when it comes to the cat it's nearly impossible without some form of trickery to avoid risk of being scratched or bitten because he's smarter than my dogs.

roqstar recommends this item.
Was this review helpful? 0 0

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