Image of K9 Advantix II for Dogs

Advantix is one of the most trusted names in flea and tick protection, and for good reason! K9 Advantix II is an easy to use and effective product, beginning to work within 12 hours and lasting for 30 days.

Rated 5 out of 5 by 653 reviewers.

K9 Advantix II
Love this product. No fleas! by on 03/15/2024
Works great on our dog by on 02/14/2024
It works!
My gsd husky is 73# and I've been applying this for over 2 years. He never had any issues with his skin or irritation. I start by applying on his back and work my way down as a rub it into his skin.i wear gloves to do this. Sometimes I forget to apply it on the exact date of the month and apply it a couple days later and no issues. Good product. by on 01/17/2024
Best available product!
Have used K9 Advantix exclusively for many years on all of our dogs. To my knowledge, it's the only product that repels not only Ticks and Fleas, but also Mosquitoes!! Mosquitoes spread several different threats to dogs! by on 12/13/2023
My order
The post office lost my original order and you guys took care of it immediately! Thank you so much! by on 12/11/2023
I can always count on this product to prevent and kill fleas and ticks by on 11/30/2023
No bugs
Once I found Advantix II - I never looked back. Best stuff ever by on 10/13/2023
Great way to keep ticks off your pet before they bite. by on 09/07/2023
Good product
I have been using this for my GS husky mix for almost 3 years. No allergic reactions or skin issues. He has been to daycare at Petsmart and was safe from fleas and ticks. He goes to the groomer and rolls around the grass in the yard and no issues with fleas and ticks. I prefer this product over Frontline bc its has a wider coverage such as mosquitoes coverage too. I prefer a topical medication over a pill such as Simparica Trio bc I feel it's less chemicals being ingested by my dog and it's cheaper than pills. I know that simparica and other pills have heartworm, fleas and tick prevention but the side effects of such pills are too many and risky. I'll stick to old fashioned topical ointment and a separate heartworm medication. This process seems to be working fine for my dog. by on 08/03/2023
Received fast too. by on 06/23/2023
Advantx ii
Good product by on 05/29/2023
K9 Advantix
Best product for my dogs who chase rabbits and wildlife on our farm by on 05/27/2023
Great Product
I have been using K9 Advantix for over 15 years, I have never had a problem with with. I like the fact it protects against mosquitoes as well. by on 04/19/2023
No fleas
Works great ! by on 04/07/2023
Husky GSD is ok with it
My dog is 75# and I use this once per month. Been using for almost 2 years and no skin issues. I like the full protection it provides versus Frontline. This one has a broader spectrum. I've forgotten to apply for up to 1 week and he has been fine. I also have applied on him a few days before the groomer bath visit and no problems. This ointment is waterproof and water resistant too I think. So far so good! by on 12/12/2022
Awesome product by on 10/15/2022
still finding sand lice on my dog
this is supposed to be better than the other stuff I've been using which was cheaper but my dog was having a toxic reaction to. She doesn't have a reaction to this one but now I'm finding sand lice on her so I don't know if it's not strong enough? by on 07/26/2022
Love this product. I've given this to both my dogs for 2 years now and i will continue to do so. Great protection. by on 07/13/2022
Dog Food
I use Pedigree adult steak flavored food for my dog. I also purchase the 55lb bag. I wish you would carry that flavor and size. by on 03/23/2022
So far so good
I've been using k9 advantix topical in my dog for about 1 year. My dog was 6 months old when I realized that we needed protections against fleas and ticks. He's mostly an indoor dog and it's not around other pets just humans so I didn't think he needed this protection. Hiwever I read that even when taking a walk and peeing in the grass or passing by another dog he can get those nasty bugs. I'm not risk it. I have kids and I don't want to deal with that infestation. I started using Simparica Trio but 1. It causes seizures 2- read bad reviews and 3- too expensive. Yes it has a broad spectrum of coverage bc it prevents heartworms. So I'm doing this topical cream along with another medication for worms. Some people want sowmthing easy for their dog on a monthly basis which I understand bc my dogo is diff sometimes when apphung this ointment but he vebtually let's me. I start on his back. Open his fur to expose his skin. Drop a small drop on the skin and smear it a little so it doesn't run. I do this in a straight line across his back all the way down to the tail. I use the whole product for each application. It's been 1 yr and no skin issues. I just watch him for about an hour afterwards to make sure he doesn't lick it. This is waterproof. Sometimes I apply it and take him to the groomers for a bath the next day. Directions say you can shower your pet and product stays in. I feel good that my I'm using this preventive product to ensure I dint have to deal with those nasty bugs. Product is pretty safe and no issues in 1 yr. I know other dog owners that have used this for many years woth no issues. It's a well established product and that's what I need. by on 03/06/2022
Good for husky GSD
I have been using this topical ointment for almost 1 year. My pup is 17 months old. So far so good. I place a several drops along his back all the way down to his tail u til the product is completely gone. I watch him for a couple of hours until it dries so he doesn't eat it. No itching or allergies seen while using this product. Make sure it goes on his skin and not in his fur. I wore gloves and smear it a little bit after applying it. I like this product better than simpatica. For worms I use interceptor plus so I have full coverage but no side effects like simpatica that can chase seizures and cognitive disorders. There are side effects to with k9 and interceptor but they are less then simpatica. My dogo is doing good with this k9 advabtix product. He is 75 pounds. I use the e tire container for each application. 1x per month. by on 02/01/2022
I love this type of topical. It not only repels fleas, flies and mosquitoes, but keeps them away from us too. by on 12/30/2021
K9 Advantage
Product works great. I wish it came in a chewable. by on 12/20/2021
Great stuff
Works great itโ€™s the only brand we use for our girls! by on 11/29/2021
Great stuff by on 07/12/2021
Great Product!!
I've used K9 Advantix II for dogs for many years through 2 golden retrievers and they never got any fleas, ticks, worms, or any kind of critters on their bodies. With all the hair they have, that is a major accomplishment! I strongly recommend this product, which in addition to working well is less expensive than competing brands. by on 02/21/2021
max had it for 10 years
my dog max has had it for 10 years and no complaints seems to workk espeically we have lots of ticks in the back yard and hardly see any on him after we go out by on 01/03/2021
Love this product!!
I've used K9 Advantix II for dogs for 10+ years for my 15 yr old golden retriever rescue. While she doesn't stay outside for long periods of time, she loves to lay on the grass when it's sunny and walks through landscape areas all the time. She has NEVER had a flee or tick or any type of worms and we have never found either in the house. That is proof positive Advantix II works and the price is much better than some of the other treatments. Sadie and I couldn't be happier!! by on 11/07/2020
Does more for the same price
The K9 Advantix II also protects from mosquitoes as well as flea and tick. I would not trust my beloved pet to anything else. by on 07/02/2020
Advantix II
Advantix II is my go to flea control because it also is a mosquito repellent. by on 06/12/2020
i have been using this product for `11 yrs. no problems. recommended by vet. by on 06/07/2020
Have been using this product for many years and my dogs have not had any fleas. by on 05/04/2020
very good
i have been using this product for 11 yrs. no problems what so ever. by on 03/20/2020
Never had an issue
Never had a problem with this, easy application and quick working time by on 01/03/2020
The best stuff!!
This is the *ONLY* stuff I've used over the past 30+ years that actually kills the fleas and ticks. If the house is already full of fleas, putting this on your dogs (assuming it's just dogs and not cats in the house) *WILL* end the infestation within two months (two applications). I live in TN. We have every bug known to man here and in numbers that make the Amazon basin blush. The ticks here are just as thick as any flea problem you might run into ever. This stuff keeps my dogs absolutely, completely tick/flea free...and, we have a pretty good-sized pond that they swim in daily when the weather and water is nice enough for them. This stuff still doesn't wash out. Even though it says it's waterproof, one wouldn't expect it to actually be so with that much swimming they do per day (and night! They love to chase the bullfrogs off the banks into the pond!), but it stays on them and they remain bug free. I've seen dogs that I wanted to beat the owners senseless for because the poor dogs were eaten up with fleas or ticks and the poor dogs were wearing themselves out constantly scratching. It made me proud that I used something that works so well on my own dogs.'s a water(?) based, not oil based, so it spreads really fast and goes through the hair and down to the skin really fast and easily, so nowhere near the mess and loss of the stuff. No one on the planet at present has the money to pay me to get me to stop using K9 Advantix, and I'd be absolutely devastated if I was to find some day that it wasn't being made anymore. by on 12/12/2019
Great product
We love K9AdvantixII...easy to use, works great. No fleas, ticks or mosquito bites- which means no heartworm risk, or Lyme, or any other associated illnesses! Purchasing through PetCare is the most affordable way to safely protect our dog, and without a reliable, affordable product, Casey wouldn't be able to spend time doing what he loves- spending time with us outdoors! by on 10/22/2019
This product works the best. Since I've started using this, we have had not ticks or fleas! by on 10/09/2019
Good Product
I used front line before, and switched into advantage. Worked wonders. by on 08/16/2019
My fave medicine
Have been issuing it for over two years and haven't had any issues ever! by on 08/02/2019
Weak Results
Not sure why my dog is scratching just 2 weeks after applying the Advantix. I had been using Frontline for years and it would last a month or longer. Nothing else has changed. I'm a bit disappointed in the Advantix II. by on 06/28/2019
effective for ticks and mosquitos
used this for years after switching from frontline. goes on easily and lasts for several weeks, even with dogs swimming and frequent baths in the summer months. by on 06/06/2019
Always seem to be able to count on it
I have used K9 Advantix II for my dog for 9 years... it has only let me down once in all that time and even then the company made it right!! by on 06/04/2019
Ease of order
Products have been great and the price is reasonable. thank you. by on 04/26/2019
Flea & Tick
Great Product! No fleas or ticks on dogs or in the yard. No side effects! by on 02/04/2019
Works Perfectly
We use a Sentinel heartworm medicine that also eliminates fleas, and this flea medicine only make it extreme on protection. We have been around dogs and cats that did have fleas and our dog has not had 1 single flea touch him. The double wammy of meds keeps him flea free. by on 12/03/2018
K9 Advantix II works!
I've been using this for 2 years now and it keeps my two dogs flea and tick free. by on 09/09/2018
No Fleas
We have 5 dogs, 3 Goldens & 2 Labs...product works great. by on 07/26/2018
time for a change
I have used this product for 3 years. I have always found ticks on my 3 dogs but was told that even when they bite thru the skin the ticks will die. Now, I have been finding full ticks on them and one of my dogs was just diagnosed with anaplasmosis in her bloodwork. Fortunately, she does not show symptoms but the vet treated her with a long course of antibiotics. Last month, I switched her to Bravecto but kept my other two Goldens on K9 (I have a years supply still) This month, I have not found any ticks on my Bravecto dog and I have found several on my K9 Advantix dogs! I am know getting rid of all the unused K9 and switching all my dogs to Bravecto. There is also a $15 online rebate available for Bravecto. by on 06/05/2018
good value
product was mailed fast, works great by on 06/05/2018
Works great - less smelly
Virtually no smell - unlike Hartz First Defense by on 05/30/2018
Don't Recall Using Anything Else!!
My baby girl is 13 and we adopted her from a Golden Retriever Rescue society in Dallas when she was 5. Sadie is our third golden and we've used Advantix II for all of them and have never had fleas or ticks or any other unwanted critters on them or in our house. All of our dogs are mainly indoor but do go outside several times a day for walks and just to check out anything new in the neighborhood. We've always had cats also and even though we don't use Advantix on them, they're the proof that the dogs don't bring anything inside. So I'm a very happy camper and will always use this product. Thank you. by on 05/08/2018
Greatest flea/tick product
We started using this product with our Shelties 18 years ago. Only had one incident with a tick years ago. I truly recommend this product. It's easy to apply and waterproof. You just can't go wrong! by on 04/23/2018
Great product!
I have been using k9 Advantixll on my dog for 2 years! I have never seen a flea. Keep up the good work. I like the fact that k9 Advantixll repels and kills fleas, ticks and mosquitoes and it is waterproof! by on 02/22/2018
no odor
no odor (unlike other products), no fleas! by on 12/11/2017
Good stuff!
I've never seen a flea or tick on any of my dogs using this product. by on 06/28/2016
Waste of money
This product d d not work at all. Good thing I didn't order the 6 month supply! by on 06/16/2016
This product was at a great value.
I am very pleased with the prices and the delivery of my product. I will be using PetCarRx in the future and will be recommending it to my friends and family. by on 06/11/2016
Works better on ticks than the competitors
Ticks are our biggest problem. Our dog goes in the woods a lot and tends to pick up ticks. Advantix II seems to work better than the other products on the market. by on 05/30/2016
Easy to use
We have used K9 Advantix II for Dogs for years and we highly recommend it, our pets have not had any problems with fleas or ticks. by on 05/23/2016
We used to have a tick problem
We live in a nature area with lots of trees, mulch, bushes, etc. and several times, we found ticks on our cocker spaniel until we started using K-9 Advantix II. Now, "There ain't no bugs on me", is the song we're singing. Also, in checking on side effects, this product seems to have less issues. by on 05/21/2016
Not very effective this season
Last year we didn't seem to have a problem, but for some reason this year, we are getting A LOT of ticks, even 5 days after application. I don't know if it is a bad batch and maybe a particularly bad tick year, but we are going to keep trying and see if it was just a fluke. I did add a collar on for added protection, so that will confound my results, but don't want to take risks with my baby! by on 05/16/2016
it do what it supposed to do.
Works great. been using it or 15 yrs and it has always done great. by on 05/02/2016
This product covers fleas ticks and mosquitos...
As a first line of defense for my small dogs..I prefer this product over most others. The pricing, packaging and quick delivery makes it easy to be a loyal customer.. by on 05/02/2016
2 weeks later, still scratching, no dead ticks
Absolutely ineffective. My dog got chewing lice and this made no change whatsoever in treating them. In addition, it definitely does not kill ticks. Poisoned my dog with this stuff and didn't even result in what was promised. by on 05/01/2016
I've used Advantix for many years and will continue to do so.
My Veterinarian recommends this product, so I will continue to use it for my dog as long as the Doctor thinks it appropriate. We live in a tick-infested area with lots of woods and fields with tall grasses. It is therefore necessary that we use a flea/tick preventative for our dog. I have used various collars in the past and other "liquid" products for my dogs but Advantix seems to be the best one on the market to date. by on 05/01/2016
excellent. never had any problem w/ insects on pet
Excellent product. I've never had any problem with flees, ticks or flies. My dog is comfortable walking outside. And he gives me no problem when I apply medicine. I'll continue to use this product and recommend it to friends. Thank You by on 05/01/2016
great preventative
I use k9 advantixII because it has a wide variety of preventatives for my dogs. 1 it is expensive but it is affordable thru this company. I love my babies and NOTHING is too good for them. by on 04/02/2016
i use it all the time..
great works effectively on my dog... by on 03/30/2016
Very effective. Easy to apply.
While the application does either have a burning or itching sensation for a very brief period, the results have been great in battling ticks. by on 03/24/2016
Love it
Works great we love it. Only thing that keeps ticks and Miskitos away. by on 03/19/2016
well known product .. like that it is one of the few that deals with mosquito's
down side is that it makes my dogs itch and scratch .. not that much, but gives me a flea phobia when they do it by on 03/18/2016
Really needed this. Have used Frontline Plus for years and never saw a flea. But this year we had a warm winter and with it an epidemic of fleas! They just wouldn't die! I have three terriers and they were itching like crazy. I could see fleas! Gross!!! Decided to try K9 Advantix 2 and saw the fleas fall off dead! Also had the house and lawn sprayed for extra measure. Thank you K9 Advantix 2. by on 03/17/2016
Excellant service
Petcare RX is fast and efficient ! The online site is easy to maneuver and the prices are low. A great place to purchase anything needed for my dog . by on 03/16/2016
I love k9advantix
I have been using this K9Advantix for the past few years on all four of my dogs. I don't have a flea problem and as an added bonus none of my dogs have had any problems with heartworms !!! by on 02/27/2016
I have large dog. K9 advantix works pretty good. Not sure if it really keeps mosquitoes off. by on 02/21/2016
Effective. I have never seen a flea or tick on my dogs and where is I live is "tick country"
The only reason I didn't give it a 5 paw ease of use is because for some reason my dogs do not want to stay still for me to put it on. It doesn't hurt so I don't understand it but a treat works for cooperation. So far I have no complaints about the product - just wish it wasn't so expensive. by on 01/21/2016
Effective. I have never seen a flea or tick on my dogs and where is I live is "tick country"
The only reason I didn't give it a 5 paw ease of use is because for some reason my dogs do not want to stay still for me to put it on. It doesn't hurt so I don't understand it but a treat works for cooperation. So far I have no complaints about the product - just wish it wasn't so expensive. by on 01/21/2016
Wonderful product, easy to order and quick delivery. by on 01/12/2016
Advantix II works well
I use it faithfully every month. I did find a tick on one dog twice throughout the summer. It does not work on deer or horse biting flies. by on 01/01/2016
This product cover most bases of inscent repellent & control.
Our 12 year old Yorkie has experienced NO side efects with K-9 Advantix! Unlike many of the other products available for use on small dogs. by on 12/12/2015
This product cover most bases of inscent repellent & control.
Our 12 year old Yorkie has experienced NO side efects with K-9 Advantix! Unlike many of the other products available for use on small dogs. by on 12/12/2015
No what it used to be
This product used to work great but no longer has the effectiveness that it used to have. by on 11/22/2015
My small dog had a skin reaction. Large dog tolerated it fine . I will need to go back to Advantage.
I thought I was ordering my usual meds for my 2dogs. The price was very good and shipped in a timely fashion. However, after applying Advantix II on both dogs we noticed later in evening our Shih Tzu was very restless , could not relax , began to scratch . Our Lab was fine. I realized Advantage was what I usually ordered so I called the number on the back of box and spoke with a Bayer rep. They explained it had one other ingredient than Advantage and did not go into blood stream but stayed on the skin . She gave me helpful info as to how to treatthe problem and we did . However our dog was miserable for two days as were we as he could not relax to sleep for very long without a hand rubbing the area for him. NO MORE ADVANTIX! by on 11/20/2015
Fleas seem to be immune
I have used Advantage and Advantix 2 for as many years as it has been out on my dogs and it was wonderful. This is the first year that they have had no effect at all. It was terrible for the dogs! Maybe due to the long California summer and drought conditions. I had to go to the vet to get an oral medication that seems to be working okay. by on 10/29/2015
great product that works!
This product is great and a great price! I have 3 dogs and havent seen one flea or tick on them! Highly recommended! by on 10/28/2015
No fleas or ticks with this product.
Recommended to use this product over the other brands. It works and is easy to apply. Expeditious delivery. Great value, less than store. by on 10/24/2015
great item
we have been using both for years, would not change. by on 10/21/2015
This product is very effective.
I love that I can buy quality products from this site for great prices. by on 10/21/2015
Best protection for my dog
I love the ease if ordering, navigation, and prices! This is the only place I order my dogs flea and tick medication from! by on 10/20/2015
K9advatixII is great
I like this product because it has everything that I need to protect my dog. It's kills and repels ticks, fleas at all stages. It also protect my dog from mosquitoes bits and blood-feeding flies bits. It kills chewing lice as well.I am happy with K9advatixII by on 10/02/2015
K9 Advantix II for Dogs Really Does the Job!
Our current 2 dogs don't even know what fleas and ticks are. Previous dogs, before we found Advantix II, suffered huge tick infestations, which included daily "pickings". by on 09/07/2015
Product does what it says it does. I recommend it. by on 09/04/2015
It keeps mosquitos off the dogs
South Texas had more rain in the Spring than normal and the mosquitos were rampant. K9 Advantix II for Dogs kept the mosquitos off and out of the house, which would bite me by on 09/02/2015
I have sworn by this product for at least a decade, and due to the frequency of fleas, and an occasional tick, I do wonder if these critters develop immunity. If there was another product as effective as this one, I would alternate them. Overall, it's a very good product for longer haired dogs out in the field. I'm not 100% on the toxicity and the safety to my dogs, yet after trying a variety of chemical and natural products, this is the most reliable one. by on 09/02/2015
excellent product and great value.
Pet care RX delivered! I love this product and the value that RX provides me. The ease and comfort of ordering from home plus the excellent customer service I received are worth being a xustomer. by on 08/30/2015
The Product works great, BUT...........
Look out for the 54 Dollar charge for petcare Rx Plan. you can not order this product without buying this plan. No way to put order in the cart to buy, Read careful, Bad service.... Will not order again, Bad service all the way.... by on 08/29/2015
I like the small tubes format and the fact that they are individually packaged and sealed. The cap serves as an opener to the actual tube tip as well. by on 08/29/2015
This product is great has mutiple coverage
I like this product because it helps cover my dog from fleas but also from mosquitoes. by on 08/28/2015
We have been this using this product several years and never disappointed. by on 08/19/2015
Love this product!
I have three rescue chihuahuas so keeping them healthy and happy is priority. I find that K9 Advantix II works just as it promises. We have no fleas, ticks or mosquitos in our home even though all our fur babies get to play outside several times a day. Buying in packs of 12 really saves money, too. Not one of my "kids" has ever gotten sick or had a bad reaction to K9 Advantix II. I would imagine if you bought the wrong size, it might not agree with them. Stay within the weight boundaries and you will do fine. by on 08/17/2015
Great for Summer
I use this every two months in the summer when the fleas are the worst and it works great, I would use no other product for the worst time of year. by on 08/09/2015
Nice to be able to purchase this online
I appreciate being able to purchase a quality product on line by on 08/03/2015
Works great!
Very effective great product for my chihuahua! He has not gotten bit by a biting fly or had other insects bite him since he gets this monthly! Thank u petcare Rx! by on 07/30/2015
Great prices, great Product. Save money and your pets get to live longer, healthier, and most of all happier right by your side. by on 07/29/2015
This product works well
I've used this product on my pet for many years. This is better than any other flea & tick on the market today. I won't use anything else. by on 07/25/2015
Great product!
This works wonders for my dog who also has a flea allergy. He does not have any more issues at all once I used this products. No fleas, no scratching! Highly recommended! by on 07/17/2015
Easy to use, effective, doing what is supposed to do, and no major side effects
We have used other products, some caused adverse reactions others were ok but seemed to lose their effectiveness. We switched to Advantix II and have had good results. by on 07/15/2015
product is good but
My dog has responded well to this product for years. The problem with this purchase has been the constant hounding with emails from Pet Care Rx. Everytime I opt out, the number of emails I get increases. I now receive 3-5 emails per day mostly telling me to buy more of what I just bought a 6 month supply of.Pet Care Rx was a few dollars less than the competition. Though, in 6 months, it will be worth the extra expense to purchase the product from a company that doesn't ignore my simple requests. by on 07/12/2015
There ain't no Bugs on me!!!
Best flea & tick prevention ever! And it's so easy to use. Have been using it for over 10 years and never had a problem. by on 06/06/2015
Great product
We have been using this product for years. It is very effective and keeps away the fleas and ticks! by on 06/06/2015
Product works very well
Use this on my aged beagle. I use a flea comb to check for critters. Have yet to find one. Also have not found one tick. She has experienced serious reactions to other products. K-9 advantix is perfect for her. by on 06/05/2015
It's Great!
We have used K9 Advantix II for a couple of years on our 2 dogs and have not had a single critter infestation! The price is right, the shipping prompt, and the product is great. Thanks!