ZoGuard Plus for Dogs
ZoGuard Plus for Dogs
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At a Glance
Protects dog parasite infestation and puts a stop to the flea life cycle
Fipronil disrupts insectโ€™s neuromuscular and central nervous system
(S)-methoprene chemical controls every stage of a fleaโ€™s life cycle
One monthly topically application works for the next 30 days

ZoGuard Plus for Dogs

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At a Glance
Protects dog parasite infestation and puts a stop to the flea life cycle
Fipronil disrupts insectโ€™s neuromuscular and central nervous system
(S)-methoprene chemical controls every stage of a fleaโ€™s life cycle
One monthly topically application works for the next 30 days

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Total Price

ZoGuard Logo

Ultimate Guide to ZoGuard Plus for Dogs

Meet the 3-to-1 Parasite Killing Liquid: ZoGuard Plus for Dogs!

ZoGuard Plus for Dogs is a veterinarian-recommended dog medication that protects your dogs from dangerous external parasites - fleas, ticks, and chewing lice. ZoGuard Plus for Dogs is a monthly, spot-on application therapy that also prevents Lyme disease. ZoGuard Plus for Dogs guarantees pup comfort.

How does ZoGuard Plus for Dogs work?

ZoGuard Plus for Dogs is a medication with the two active ingredients that are also in Frontline Plus for Dogs - Fipronil and (S)-methoprene - that kill chewing lice, ticks, and attacks the flea's life cycle. ZoGuard Plus kills the parasites on contact by storing itself in the oil glands in your pet's skin and hair follicles continuously for the next 30 days.

Fipronil for dogs is a phenylpyrazole insecticide that disrupts the insect's central nervous system by blocking the GABA-gated chloride channels that regulate cellular excitability to the contaminated insect's neuromuscular system and glutamate-gated chloride (GluCl) channels that control movement, feeding, and behavior.

(S)-methoprene is an insecticide chemical that controls hatching eggs, obstructs the development of the immature flea (i.e., flea pupae and larvae) into a breeding adult, and proper growth into a healthy viable adult flea. Together, these active ingredients deter parasites and put a stop to the flea life cycle.

How is ZoGuard Plus for Dogs administered?

ZoGuard Plus for Dogs is administered topically once a month and protects your dog for the next 30 days.

How to apply ZoGuard Plus for Dogs:

  1. Remove the individual tube from the packaging.
  2. With scissors, cut the notched side with lines after turning it away from your face.
  3. Part your dog's hair at between the shoulder blades.
  4. Apply the entire contents to one spot on the dog's skin.
Body Weight Box Color Fl. Oz. Per Tube
4 - 22 lbs. Orange 0.069
23 - 44 lbs. Purple 0.135
45 - 88 lbs. Red 0.273
89 - 132 lbs. Green 0.408

Available are 3 or 6 monthly doses.

What are the precautions of which you should be aware?

The following should be discussed with your veterinarian before using ZoGuard Plus or other pesticide product treatment:

  • Some medications cause negative interactions with ZoGuard or its ingredients
  • Breeding, pregnant, lactating, debilitating, or geriatric dogs
  • Undergoing skin dermatitis medications
What is ZoGuard Plus for Dogs' potential side effects of which you should be aware?

Temporary irritation may occur. Side effects are rare but any that occur should be discussed with your veterinarian.

Frequently Asked Questions
  1. What do the ZoGuard Plus for Dogs reviews say?

    ZoGuard Plus for Dogs reviews rate 4.5 out of 5 stars. Most reviewers say that ZoGuard Plus for Dogs is a highly recommended flea and tick treatment with an easy application that they trust for their furry best friend.

  2. How long does it take for ZoGuard Plus to work?

    ZoGuard Plus will kill 100% of fleas within 4 to 12 hours of the application. If there are eggs that have not yet hatched, then they would not have been exposed to ZoGuard Plus's active ingredients.

  3. How long does it take for ZoGuard Plus for Dogs to dry?

    Be sure your dog is dry before application, and keep your dog dry for 24 hours after application. Do not bathe your dog for 24 hours after application. Separate the treated dog from all other dogs, cats, and children for 24 hours after treatment has been applied. Do not apply more frequently than once every four weeks.

  4. Is ZoGuard Plus for Dogs for puppies?

    ZoGuard Plus for Dogs can be administered to puppies that are at least 8 weeks of age and weigh 4 pounds.

Concluding Thoughts

The most important thing that you should know about ZoGuard Plus for Dogs is its power to protect your dog from tiny external parasites and dangerous diseases that are connected to them.

DISCLAIMER: FDA law restricts ZoGuard Plus for Dogs only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if this is a suitable product for your pet and your home.

  • ZoGuard Brand
  • Flea & Tick Pharmacy
  • Mature Adult Life Stage
  • Senior Life Stage
  • Kitten Life Stage
  • Puppy Life Stage
  • Adult Life Stage
  • Spot On/Topical Application
  • Dog Pet Type

Is Zoguard Plus as Good as Frontline?

ZoGuard Plus is a flea and tick treatment for dogs. The tick treatment medicine contains the same active ingredients as the Frontline Plus - fipronil and S-methoprene. Therefore, yes, it's similar to the Frontline and Frontline Plus medication and is as good. The medication is intended to help dogs fight chewing lice, ticks, fleas, flea eggs, and flea larvae. Moreover, ZoGuard Plus is more affordable, which means it's more value for money. The medication is effective against all stages of the flea, which helps break the parasite's life cycle and prevents reinfestations from happening. ZoGuard Plus is also waterproof, which means it stays on even after bathing and is also safe from direct exposure to sunlight.

Does Zoguard Plus for Dogs Work?

ZoGuard Plus is identical to Frontline Plus and has the same active ingredients but at a cheaper cost. The medication offers the same tick and flea protection level as Frontline Plus and is very effective regardless of how severe the dog's flea infestation is. Every package of the ZoGuard Plus has roughly a 3-month dosage, which effectively provides 12 weeks of flea and tick protection to the dog. According to research, ZoGuard Plus has been proven to eliminate adult fleas for around three months. Pet parents should use the medication monthly to control chewing lice, ticks and prevent the chance of reinfestation. ZoGuard Plus is a waterproof medication and continues to be effective despite exposure to elements like water and sun rays.

Is Zoguard Safe for Dogs?

If used as intended, ZoGuard Plus is completely safe for dogs. However, consult a veterinarian before administering to an already medicated, debilitated, or aging dog. Moreover, it's advised to practice caution and consult a vet before treating a dog with known organ dysfunction and dogs with dermatitis or other skin conditions. In rare cases, your dog may react to the medications and show some symptoms. These symptoms include redness, scratching, or other discomforts. If your dog is showing any sign of discomfort after applying ZoGuard, bath it with mild soap and rinse with a lot of water. Additionally, the medication is meant only for external use. In case of ingestion, the dog may show symptoms like excessive drooling and foaming at the mouth. In such a case, immediately feed the dog and observe for the next 24 hours. If the symptoms persist even after 24 hours, consult a veterinarian immediately.

How Do You Apply Zoguard Plus to Dogs?

ZoGuard Plus for dogs is applied directly to the dog's skin on the affected area and is for external use only. To apply ZoGuard Plus on the dog, take out the individual tube from the packaging. Now, cut the notched side of the tube with scissors after turning it away from your face. Part your dog's fur at the affected area or between the shoulder blades and apply the entire content of the tube to one spot on the dog's skin. The ZoGuard Plus comes in four packages where the orange box is meant for dogs between 4-22lbs, the purple box for dogs between 23-44lbs, the red box for dogs between 45-88lbs, and the green box for dogs weighing 89-132lbs. The medication is available in packaging of 3-6 months dosage.

Is Zoguard Safe?

ZoGuard comes in four formula packaging depending upon the weight of dogs. Make sure to get the correct packaging according to your dog's weight, and the product is entirely safe. Moreover, the medication is for external use only, so exercise precaution to ensure that your dog doesn't ingest it accidentally. After applying the medication, allow it to dry completely to prevent any accidental ingestion by licking. Also, ZoGuard is a parasitic medicine and shouldn't be administered with another parasitic medication. Dog's suffering from an existing skin condition, organ dysfunction, old age, and other such conditions will require the vet's guidance before starting ZoGuard treatment.

Is Zoguard Plus Safe for Pregnant Dogs?

ZoGuard Plus medication has been certified to be safe for breeding, lactating, and pregnant dogs. The medicine contains the same active ingredient as Frontline Plus, which is proven safe for dogs with these conditions. The active ingredients are Fipronil and (S)-Methoprene, which kill fleas, flea eggs, flea larvae, chewing lice, and ticks quickly. The medication is effective for breaking the flea life cycle and preventing Lyme disease as well. The drug is also effective against mites that are the root cause of sarcoptic mange.

Is Zoguard Plus for Dogs Waterproof?

Yes, the ZoGuard Plus anti-flea and anti-tick medicine's unique selling point is that it's waterproof. After being applied and dried, the medication stays waterproof for as long as 30 days. It can survive emersion in water, bathing, rain, and even direct exposure to sunlight. However, ensure that the medication is thoroughly dried after applying to ensure its water resistance.

What can I give my dog to prevent fleas and ticks?

There are many topical treatments available that are applied directly to your dog's skin, usually between the shoulder blades. These treatments typically contain active ingredients such as fipronil, imidacloprid, or selamectin, which kill and repel fleas and ticks. Examples include ZoGuard Plus, Frontline, Advantage, and Revolution. Oral flea and tick medications are available in tablet or chewable forms. These medications work by either killing or inhibiting the reproductive capabilities of fleas and ticks when they bite your dog. Some popular oral medications include Bravecto, NexGard, and Simparica. Flea and tick collars contain active ingredients that repel and kill fleas and ticks. These collars are worn around your dog's neck and provide protection for a specified period. Examples include Seresto and Scalibor collars. Be sure to choose a collar specifically designed for dogs, as some products meant for other animals can be toxic to dogs. Flea and tick shampoos and sprays are also effective options for preventing infestations. These products contain insecticides that kill fleas and ticks on contact. However, they may have limited residual effects, meaning they do not provide long-term protection. Regular use may be required, especially during peak flea and tick seasons.

What is the safest flea prevention for dogs?

The Natural Resources Defense Council (NRDC) recommends using products containing the active ingredients s-methoprene or pyriproxyfen as alternatives to potentially more toxic chemicals for flea and tick control. S-methoprene and pyriproxyfen are insect growth regulators (IGRs) that disrupt the life cycle of fleas and ticks, preventing their development and reproduction. These ingredients are considered to have a lower toxicity profile compared to some other chemicals used in flea and tick control.

What is a natural flea killer for dogs?

There are several natural options you can consider as flea killers for dogs. While they may not be as potent as chemical products, they can still help in reducing and managing flea infestations. Diluted apple cider vinegar can be used as a rinse after bathing. Mix equal parts of apple cider vinegar and water and pour it over your dog, avoiding the eyes and sensitive areas. Fleas dislike the smell and taste of vinegar, which may help repel them. Certain essential oils have natural flea-repellent properties. Dilute a few drops of essential oil such as lavender, peppermint, eucalyptus, or cedarwood in water, and lightly spray it on your dog's coat. Remember to use essential oils sparingly and with caution, as some dogs may be sensitive to them. However, these natural remedies may not be effective in eliminating a severe flea infestation.

Does coconut oil repel fleas and ticks on dogs?

Coconut oil has been claimed to have some flea and tick-repellent properties, but its effectiveness in repelling these pests is not well-documented or scientifically proven. While coconut oil may have some benefits for the skin and coat of dogs, it should not be solely relied upon as the primary method for flea and tick prevention. If you choose to use coconut oil as a supplement for your dog's overall skin health, it should be used sparingly and in moderation. Too much coconut oil can lead to digestive upset and weight gain, as it is high in fat and calories.

Do indoor dogs need flea prevention?

Yes, indoor dogs can still benefit from flea prevention measures. While indoor dogs may have a lower risk of encountering fleas and ticks compared to dogs that spend more time outdoors, fleas can be brought into your home through various means, such as on your shoes, clothing, or other pets that go outside. Additionally, fleas can also hitch a ride on other animals, like rodents, or infestations can occur from previous residents. Fleas can quickly multiply and infest your home, leading to discomfort for your dog and potential health issues. Flea bites can cause itching, allergic reactions, and even transmit diseases. Therefore, it's prudent to take preventative measures even if your dog primarily stays indoors.

Fipronil..................9.80% (S)-methoprene....8.80%

For external use only. Although rare, some sensitivities can occur when using pesticide products on dogs. Speak with your vet to discuss any current medications and how it may react with ZoGuard Plus for Dogs. Follow manufacturer instructions to ensure an overdose does not occur, as overdosing can cause serious illness or death. Speak with your vet if your dog is pregnant, nursing, using other medications, aged, or has any debilitating condition before treating your dog with ZoGuard Plus. Dogs undergoing any skin dermatitis medications should speak with your vet before applying ZoGuard Plus for Dogs.

Once removed from packaging, separate an individual tube from its grouping. Keep notched side of tube pointed up and away from your face and body. With scissors, cut the notched side with lines.

Using the cut end of the tube part your dogโ€™s hair at the shoulder blades, and apply the treatment by applying directly to your dogโ€™s skin. Dose every 4 weeks, do not apply more treatments less than 4 weeks apart.

Temporary irritation may occur โ€“ supervise your dog and if any reactions persist, speak with your vet.

Option UPC/SKU
5-22 lbs 3 month supply 859837005005
23-44 lbs 3 month supply 859837005012
89-132 lbs 3 month supply 859837005036

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Dr Marty

My dog did lose weight on this dog food. I went off of it for awhile and he gained weight. So I am reordering the small dog blend

Eileen Whitt recommends this item.
Was this review helpful? 0 0

A great product

Keeps the bugs off my pups

Stephanie recommends this item.
Was this review helpful? 0 0

Just what I was looking for at a great price, but with some unexpected results.

One word of caution when using this product: Don't let your dog rub up against your leather furniture. After I applied it to my dog she got up on the couch to lay in her usual spot. When she did, the area on her shoulders that I applied the ZoGuard to came in contact with the leather backrest portion on the couch. Almost instantly it removed some of the dye and left a rather sizeable light spot. Hopefully I can locate a product to repair it. What a surprise, to say the least!

Chinnook recommends this item.
Was this review helpful? 5 1

Worth it!

I was wary of switching from my usual product but this is just as good if not more effective. Highly recommend.

BrunoDaisy recommends this item.
Was this review helpful? 7 0

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