Click to zoom Tap and hold to zoom
Refills on File
Your pet {{refill.petName}} has {{refill.refillsRemaining}} refill{{refill.refillsRemaining>1?'s':''}} for ‘{{refill.options}}’ which will expire on {{refill.expiresOn}}.
{{refill.petName}}'s refills for this have expired on {{refill.expiresOn}}
At a Glance
Revolution is a monthly liquid medication that is made for cats and dogs.
Revolution is administered via a spot-on applicator.
The medicine absorbs into the petโ€™s skin and enters its circulatory system so that any biting insects die instantly.
The active ingredient Selamectin is a highly strong parasiticide interferes with the nervous system of insects and worms.
One administered application per month works for the next 30 days.


List Price:
{{list_price * quantity | currency}}
List Price:
{{list_price * quantity | currency}} {{(list_price + 0.01) * quantity | currency}}
List Price:
{{list_price * quantity | currency}}
List Price:
See price in cart
List Price: {{list_price * quantity | currency}}
25% OFF w/code: CARE25
PetPlus Price:
{{petplus_price * quantity |currency}}
PetPlus Price:
See price in cart
Sale Price:
{{sale_price * quantity|currency}}w/code {{siteCode}}
Your Price:
{{map_price + 0.01 | currency}} See price in cart w/code {{siteCode}}
{{petplus_savings_amount * quantity|currency}} ({{petplus_savings_percent}}%)
{{coupon_savings_amount * quantity|currency}} ({{coupon_savings_percent}}%)
Join PetPlus today and get this for {{intro_price_total|currency}}
Join PetPlus today and {{use_strict_map_rules?"see price in cart":"get this for a special price"}}

inlowout of stock
Get notified as soon as this becomes available
Thank you.
We will email {{notifyEmail}} when this is back in stock.
Recommended Alternatives:
Limit ( {{ selected_sku_data.cartLimit }} ) per customer. Orders for more than this may not be fulfilled.
Shipping is always free with PetPlus | Arrives in 1-3 days on average
Free shipping over $48* | Arrives in 1-3 days on average
Select Autoship options at checkout
At a Glance
Revolution is a monthly liquid medication that is made for cats and dogs.
Revolution is administered via a spot-on applicator.
The medicine absorbs into the petโ€™s skin and enters its circulatory system so that any biting insects die instantly.
The active ingredient Selamectin is a highly strong parasiticide interferes with the nervous system of insects and worms.
One administered application per month works for the next 30 days.

Frequently Bought Together

Total Price

Zoetis Logo

Ultimate Guide to Revolution

Meet the Powerful Parasite Protector: Revolution!

Revolution is the veterinarian-approved dog and cat medication that protects your pets from various dangerous internal and external parasites. It is considered a 6-to-1 parasite killer because it is a monthly topical solution that treats 6 parasites in 1 monthly liquid dose.

It is a monthly topical solution that helps treat and prevents heartworms, ear mites, fleas, canine sarcoptic mange (i.e., scabies), and the American Dog Tick in dogs, and cures heartworms, fleas, ear mites, roundworms, and hookworms in cats. Revolution ensures that your pets are in the best condition.

How does Revolution For Dogs and Cats work?

The generic medical name for Revolution is Selamectin, which is the only ingredient in the medication. The active ingredient selamectin is a topical parasiticide and a strong avermectin endectocide to treat dogs and cats for their parasite problems.

As an antiparasitic agent, Selamectin interferes with the nervous system of insects and worms which causes their death. After the application and absorption of the medication, the treatment is carried by your pet's circulatory system. Any parasite that bites your pet and ingests their blood means certain death for them.

How to apply Revolution?

Revolution is applied via a spot-on applicator once a month to the dog's or cat's skin at the base of its neck. Spot-on treatment absorbs liquid medicine in seconds and provides complete 30-day protection from dangerous internal and external parasites.

Spot-on treatment is usually packaged in individual liquid doses. Revolution's liquid medicine is poured onto the nape of the pet's neck between its shoulders and then is slowly absorbed into your pet's skin.

What should pet owners ensure after application?

The owner should prevent the pet doesn't trying to rub off the medicine. That includes rolling on the floor or against any household items. They shouldn't allow their pet to return to play for as long as they can manage. The treated pet should stay away from untreated pets for at least 24 hours.

This causes maximum effectiveness for the Revolution medication.

What are the potential side effects of which you should be aware?

Examine dogs for heartworm disease before using Revolution.

The most common adverse reactions reported are temporary hair loss, vomiting, drowsiness, lethargy, redness, drooling, rapid breathing, increased heart rate, muscle tremors, decreased appetite, and diarrhea.

Watch out for lack of coordination and salvation, because these can be symptoms of an overdose! Call your veterinarian immediately!

Frequently Asked Questions

  1. Is Revolution for puppies and kittens?

    Revolution can be administered to puppies that are at least 6 weeks old and kittens that are at least 8 weeks old.

  2. How much is the Revolution dosage?

    Apply Revolution with a spot-on applicator (pipette) depending on the pet's weight. For example, a dog that weighs less than 5 lbs uses a .25 ml pipette to apply 15 mg per month versus a dog that weighs 20.1 to 40 lbs uses a 2 ml pipette to apply 240 mg per month. And everywhere in between.

    A cat that weighs less than 5 lbs uses a .25 ml pipette to apply 15 mg per month. A cat that weighs 5.1 to 15 lbs uses a .75 ml pipette to apply 45 mg per month.

  3. What do the Revolution reviews say?

    Revolution reviews demonstrate 4.5+ stars out of 5. Most reviewers say that this product is effective, necessary and that it keeps their pets pest-free. Reviewers trust its excellent protection for their furry best friend.

    The few unsatisfied customers have found that Revolution is ineffective in killing external parasites and their infestations.

  4. Is Revolution unsafe for certain cats and dogs?

    Revolution is safe for administration in pregnant or lactating dogs or cats. Revolution is unsafe to use if the animal hasn't been tested for heartworm disease. It is also unsafe for sick or underweight pets, and also some breeds of sensitive dogs that have the genetic mutation MDR1 (e.g., collies or sheepdogs).

  5. How long does it take for Revolution to work?

    In a laboratory study, Revolution started to kill fleas within 12 hours of the treatment and removed almost 100% of the fleas within the first day.

    According to VCA Hospitals, fleas will start dying in the first 4 to 8 hours, but full effectiveness takes several days against fleas. For dogs, it can take up to 5 days to kill most ticks that are on their skin.

  6. What other precautions should you take with Revolution usage?

    Make sure that the pet's hair isn't wet before application.

    Do not apply the liquid solution to broken skin because the alcohol in the solution will cause pain to your pet.

    Keep the liquid solution away from humans and their skin. This includes avoiding massaging medicine into the pet's skin after application.

    Be aware of combining some medications with Revolution for dog breeds with the genetic mutation MDR1.

    Do not bathe your cat for 24 hours after the application, but two hours for dogs.

Concluding Thoughts

The most important thing that you should know about Revolution is that its mission is to cure your cats and protect your dogs from microscopic mites to fleas and tick infestation to internal worms that can have a dangerous effect on their organs.

DISCLAIMER: Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition.

  • Zoetis Manufacturer
  • Zoetis Brand
  • Heartworm & Deworming Pharmacy
  • Flea & Tick Pharmacy
  • Spot On/Topical Application
  • Cat Pet Type
  • Dog Pet Type

Is Revolution a Good Flea Treatment?

Revolution is a dog and cat medication that is approved by the veterinarian for safe usage on your pets. Revolution kills adult fleas, flea eggs, and flea larvae. Revolution for cats and dogs completely eradicates up to Ninety-eight percent of the flea population within the thirty-six hours of its application. For Revolution to work efficiently on your pet, you must ensure that the liquid is appropriately applied with spot-on application on the catโ€™s or dogโ€™s skin at the base of its neck. This spot-on application of Revolution absorbs liquid medicine within a few seconds. Revolution is applied once a month. This provides your pet with thirty days of complete protection from both external and internal harmful parasites.

How Long Does It Take Revolution to Kill Fleas?

The drug Revolution whose main ingredient is Selamectin which is a topical parasiticide. This drug can be applied to both cats and dogs when appropriately administered to your pet. It effectively starts killing the fleas within twelve hours of its initial application. After twenty-four hours of treatment, it efficiently kills off almost ninety-eight percent of the flea population that is present in your petโ€™s body. In the course of the following week, Revolution starts to exterminate the newly infested fleas within six hours. From the period of twelve hours to the twenty-eighth day Revolution eliminates approximately ninety-three percent of the flea population.

Does Revolution Flea Treatment Require a Prescription?

Revolution is not an over-the-counter drug. It can only be bought with a prescription that is provided by your petโ€™s veterinarian. The application of just a few drops of Revolution on your petโ€™s shoulders can completely exterminate both internal and external parasites. If you do not have the prescription it is highly recommended that you consult a reputable veterinarian for the proper diagnosis of your petโ€™s ailment.

Is It Ok if My Cat Licks Revolution?

Revolution is a topical solution for both cats and dogs. You can apply Revolution on the base of your catโ€™s neck just above its shoulders or in any region of the coat where he or she may be unable to reach. You must apply Revolution to your pet with a spot-on applicator. To your cat, the taste of the medicine is very unpleasant and because of this reason, they may try to remove or get rid of it. If by chance your cat is sensitive or has consumed or ingested a copious amount of Revolution, it may show signs of indigestion, depression, lethargy, or seizures. These ailments can not be counted as side effects of the medicine.

What Happens if a Dog Licks Revolution?

If by any chance you have accidentally given your dog the medicine orally or your dog has ingested Revolution from the area of application of dosage in its body by licking it. Then generally, drooling may most likely occur in your dog. If excessive drooling of your dog persists for a long time, your pet may exhibit some indication of stomach upset. Your pet may feel nauseous throughout the day because of its upset stomach. In the course of this period, you must keep your pet as calm as possible. So that your pet does not feel any more discomfort or irritation during this time.

Do Fleas Fall Off After Treatment?

After the initial application of Revolution in your cat or dog, you will notice a very good lingering effect of the medicinal residue. This indicates that the medicine will carry on to work for some time if it is left undisturbed. The adult flea population that is present in your petโ€™s body will be killed within a few days. You should keep your floor clean either by vacuuming sweeping for at least two weeks after the treatment of Revolution. This is because there will still be some remaining flea eggs that will continue to hatch even after the extermination of all the adult fleas.

Can You Give Revolution to a Cat With Heartworms?

You can safely administer your dog with Revolution if it is infected with adult heartworms. Revolution is a very affordable and effective parasiticide for your pets that are easily available in the pharmaceutical market. In the case of cats and kittens, if your pet is older than six months it is advisable to contact your veterinarian for additional instruction. Your veterinarian may choose to test him or her for any existing heartworm infections. If it is found out that your cat is suffering from such ailment, for the prevention of heartworm disease, he may prescribe Revolution to your per for its complete recovery. Revolution can be administered to cats that are infested with adult heartworms for the prevention of further infestation.

Do Vets Recommend Revolution for Dogs?

Yes, they do. Revolution is a medication commonly prescribed by veterinarians for dogs to treat and prevent various conditions, including heartworms, fleas, ticks, ear mites, and some types of intestinal parasites.

How Long Does Revolution for Dogs Last?

The medication is formulated to provide long-lasting protection, with each dose typically protecting the dog for one month. However, the exact duration of effectiveness may vary depending on the individual dog's health status and environmental factors, such as fleas or ticks in the dog's living area.

What Is as Good as Revolution for Dogs?

There are several medications that are similar to Revolution and are effective at preventing and treating a range of parasites in dogs. The most commonly used medications include Frontline Plus, Sentinel, Advantage Multi, and Bravecto.

Is Revolution a Dewormer?

Although Revolution has a modest effect against some intestinal parasites, including hookworms and roundworms, it is not generally advertised as a dewormer. Instead, it is frequently used as a prophylactic step to safeguard dogs from various potentially detrimental parasites.

What Is the Side Effect of Revolution on Dogs?

When administered as recommended, dogs usually think Revolution is safe and well-tolerated. However, some dogs may develop negative effects. The most frequent adverse effects include moderate skin rashes, hair loss, nausea, diarrhea, and fatigue. Seizures and neurological disorders are uncommon but can occur. Lastly, Revolution or any of its components may cause more severe reactions in hypersensitive dogs.

Can I Touch My Dog After Applying Revolution?

No. After applying Revolution to your dog, it is recommended that you avoid petting or touching your dog in the area where the medication was applied until it has completely dried. This prevents the medication from rubbing off onto your skin or clothing, which could cause skin irritation or other adverse reactions.

How Often Can I Give My Dog Revolution?

Revolution should be administered as a monthly topical dose to provide continuous protection against fleas, heartworms, ear mites, and some intestinal parasites. In some cases, a second monthly dose may be required, mainly if your dog is at a high risk of parasite exposure or if there are already existing parasite infestations.

Can I Bathe My Dog Before Applying Revolution?

No. Do not bathe your dog within 2 hours after applying Revolution to ensure the medication is absorbed properly. Bathing your dog too soon before or after application may decrease the effectiveness of the medication by washing it off or interfering with its absorption.

Is Revolution Safe for Dogs With Certain Medical Conditions?

Revolution may not be recommended for use in dogs with certain neurological or seizure disorders, as it can cause or exacerbate these conditions in some cases. Similarly, Revolution may not be recommended for use in dogs with liver or kidney disease, as these conditions can affect the metabolism and elimination of the medication from the body. Additionally, Revolution may not be safe for puppies under the age of 6 weeks or dogs that are allergic to any of the medication's ingredients.

Can Revolution Be Used on Dogs With Sensitive Skin?

Some dogs may experience mild skin irritation, hair loss, or other skin reactions after application. But most dog breeds are tolerant of Revolution.

What Should I Do if My Dog Has an Adverse Reaction to Revolution?

You should call your veterinarian immediately if your dog reacts adversely to Revolution. Skin irritation, hair loss, nausea, diarrhea, fatigue, and, in very unusual circumstances, convulsions are a few potential warning symptoms of a bad response. You should immediately seek emergency veterinary treatment if your dog has a severe response, such as difficulty breathing, swelling, or collapse.

Can Revolution Be Used in Conjunction With Other Worming Medications for Dogs?

Using Revolution in conjunction with other worming medications for dogs is generally not recommended, as this can increase the risk of adverse reactions or medication interactions.

How Should Revolution Be Stored?

Revolution should be stored below 30ยฐC (86ยฐF) and away from heat, sparks, open flames, or other ignition sources, as it is a flammable liquid. After application, empty tubes of Revolution can be disposed of in your normal household refuse. However, keeping the tubes out of reach of children and pets is important to prevent accidental ingestion.

Revolution for dogs and cats contains Selamectin

Revolution for dogs and cats is well-tolerated by pets, with less than 1% displaying symptoms. Some exhibited temporary hair loss or skin irritation at the application site. More serious symptoms may include excessive drooling, rapid breathing, lack of coordination, vomiting, or diarrhea; consult with a veterinarian immediately if these appear.

Never administer Revolution in animals that are allergic to it. Do not use the drug on puppies or kittens under 6 weeks of age. Use with caution on sick, weak or underweight animals. However, Revolution is safe for administration in pregnant or lactating dogs or cats. Never apply the medicine on wet hair. Examine dogs thoroughly for heartworm disease before using Revolution.ย 

Revolution is a topical once-a-month pet medicine, which helps treat and prevent heartworms, fleas, ear mites, sarcoptic mange and certain types of ticks in dogs. It also cures heartworms, fleas, ear mites, hookworms, and roundworms in cats. Revolution is a semi synthetic avermectin antiparasitic agent, which interferes with the nervous system of insects and worms, causing their death. Revolution is usually available as spot on applicators and is applied once a month to the skin at the base of the neck. Apply the medicine depending on the weight of the dog. Spot on applicators are available in 0.25 ml (15 mg/tube), for dogs weighing up to 5 pounds; 0.25 ml (30 mg/tube), for dogs weighing from 5.1 to 10 pounds; 0.5 ml (60 mg/tube), for dogs of 10.1 to 20 pounds; 1 ml (120 mg/tube) for dogs of 20.1 to 40 pounds; and 2 ml (240 mg/tube) for dogs weighing from 40.1 to 80 pounds. For dogs, apply one pipette topically every 30 days. Spot on applicators are available in 0.25 ml (15 mg/tube) for cats weighing less than 5 pounds. For cats weighing from 5.1 to 15 pounds, 0.75 ml (45 mg/tube) pipette is available; apply one pipette once monthly. The major side effects of the drug often include temporary hair loss, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors. The symptoms of overdose mainly include salivation and discoordinated.ย 

Ask your veterinarian about using Revolution for dogs and cats, or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Revolution for dogs and cats is for once-monthly (preferably on the same date each month) use either year round, or only during mosquito season. To administer Revolution, part the hair between your petโ€™s shoulder blades and apply the contents of a tube of the proper dose to the skin. Dosage is dependant on weight; consult with a veterinarian to determine the proper amount.

Store Revolution for dogs and cats at room temperature.

Revolution is manufactured by Zoetis
Option UPC/SKU
Puppies/Kittens under 5 lbs - 3 Month Supply 087219034712
Dogs - 5.1-10 lbs., 6 Month Supply 087219034750
Dogs - 10.1-20 lbs., 6 Month Supply 087219034774
Dogs - 20.1-40 lbs., 6 Month Supply 087219034798
Dogs - 40.1-85 lbs., 6 Month Supply 087219034811
Cats - 5-15 lbs., 6 Month Supply 087219034736
Dogs - 85.1-130 lbs., 3 Month Supply 087219060223
Dogs - 85.1-130 lbs., 6 Month Supply 087219051214
Dogs - 5.1-10 lbs., 3 Month Supply 087219060148
Dogs - 10.1-20 lbs., 3 Month Supply 087219060162
Dogs - 20.1-40 lbs., 3 Month Supply 087219060186
Dogs - 40.1-85 lbs., 3 Month Supply 087219060209
Cats - 5-15 lbs., 3 Month Supply 087219060124
Cats - 15-22 lbs., 6 Month Supply 087219104279
Cats - 15-22 lbs., 3 Month Supply 087219104293

How to Order Prescriptions Online

1. Find the Right Product

Make sure it matches your pets prescription. Donโ€™t forget to compare the dosage for pills/capsules!

2. Add to Cart

Just like any other online store. Make sure the quantity matches whatโ€™s been prescribed by your vetinarian.

3. Tell Us About Your Pet and Vet

Answer some questions during checkout and weโ€™ll contact your vet and verify the prescription for you. You can also mail us the written prescription.

4. Thatโ€™s It!

If the prescription has any refills, processing your future orders for that medication can be expedited.

Related Articles

Revolution vs Frontline: Comparing Pest Preventatives

The Differences Between these Top Brands

Read More
The Top Reason's To Give Revolution To Your Dog

Keeping Your Pet Protected

Read More
Effective Deworming for Puppies: Home Remedies and Vet Medications Compared

What Works Best to Clear the Deworming Dilemma

Read More

Customer Reviews

Overall Rating

5 / 5
RATING BREAKDOWN 458 review(s)
* = required

New Product Review

Uploaded Image 1
Uploaded Image 2
Uploaded Image 3
  • {{error}}
Showing 1 - {{visible_reviews.length}} of 458

This product has no reviews yet. Write a review.

Page 1 of 1 1