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At a Glance
100% protection again fleas and ticks
Kills pests within 8 hours of administration
Once a month chewable tablet


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At a Glance
100% protection again fleas and ticks
Kills pests within 8 hours of administration
Once a month chewable tablet

Looking for Simparica Trio?

A Comprehensive Guide To Simparica Flea And Tick Medication

What Is Simparica for Dogs?

Fleas and ticks post a significant threat to your dog's health. While common, they are parasitic bugs that latch on to your dog's body and drink their blood. They can pass on many types of infections to your dog, and if the infestation is bad enough, they can even give your dog anemia. Simparica for dogs is a medication designed to prevent this.

You can use Simparica Flea and Tick Medication monthly to keep your dogs safe from these pesky parasites. This medicine protects your dog for 35 days, after which you can give your dog another dose. This is excellent for dogs who work a lot outdoors as you cannot control the outside environment.

Why Are Fleas and Ticks Bad for Dogs?

Fleas and ticks can pass on several different types of diseases. They can pass on these diseases to your pets and you and your family as well. Fleas multiply really quickly as they can say up to 50 eggs a day! Ticks can stay on your dog's body without anyone noticing for nearly a week.

Dogs can develop Flea Allergy Dermatitis, which is an allergy to the saliva of fleas. They can also transmit canine tapeworm or Dipylidium Caninim to other dogs, cats, and humans. If the flea has encountered any dangerous bacteria, it can pass that on to animals as well.

Ticks carry their own set of problems. The biggest fear with ticks is Lyme disease, which is an extremely dangerous and painful condition. They can also spread Rocky Mountain Spotted Fever, Colorado tick fever, Heartland virus, ehrlichiosis, and tularemia, among many others. Both people and dogs can be allergic to tick bites.

How Much of Simparica Should I Give My Dog?

Simparica Trio for dogs should be used at the dosage of 0.91.g per pound of weight or 2mg per kilo of bodyweight. Thus, a dog between 2.8 and 5.5 pounds should get one piece of 5mg Simparica chewables per month. A dog who is between 5.6 and 11 pounds gets one piece of 10mg Simparica chewables per month.

If your pet is between 11 and 22 pounds, you should give them one tablet of 20mg Simparica chewables. A dog who weighs between 22 and 44 pounds should get one piece of 40mg Simparica chewables per month. A dog who weighs between 44 and 88 pounds per month needs an 80mg dose of Simparica for dogs.

Finally, a dog who is between 88-132 pounds needs a 120mg dose of this medication. Ensure you weigh your dog at your vet before giving him any medication whose dosage depends on weight. You can weigh your dog at home, but the vet's office will be more accurate.

What Are the Side Effects of Simparica?

When you give your dog Simparica Flea and Tick Medication, they might get mild side effects like vomiting, diarrhea, weakness, or low energy levels. These side effects are usually mild and pass once your dog's body adjusts to this medicine.

However, if the vomiting or diarrhea doesn't stop, then you should contact your vet. Additionally, you should also contact your vet if your dog has a seizure after taking this medicine or if you see tremors in their body. Other signs you should contact your vet are if your dog has trouble walking or is stumbling around.

Frequently Asked Questions
  1. Can I Give Simparica Trio to My Cats?

    You should not give medication meant for dogs to cats. Additionally, there is tick and flea medication meant for dogs made with ingredients toxic to cats. Always ask for cat-specific medication when treating your cat for anything.

  2. Do the Different Colours Mean Anything?

    Simparica Flea and Tick Medication come in different colors according to the dosages in each tablet. The yellow box has 5mg of Sarolaner in each pill, purple has 10mg, orange has 20 mg, and mint has 40 mg. Finally, the green box has 80mg Simparica chewables while the brown box has 120mg Simparica chewables.

  3. How Often Should I Give This Medicine?

    You should give Simparica for dogs once a month. The medicine is effective for 35 days. Thus, even if you forget to give this medicine exactly 30 days later, you have a window of 5 days to give another dose.

  4. How Should I Administer This Medicine?

    You can give Simparica for dogs orally. This medicine is in the form of a chewable tablet. Simparica reviews show that most dogs find this highly palatable and have no trouble eating this. If your dog is a fussy eater, you can wrap this tablet up in some boiled chicken or other high-value treats, so your dog eats the full dose of this medicine.

  5. Are There Any Other Precautions I Should Take When Giving This Medicine?

    You should not give Simparica Flea and Tick Medication to dogs who are less than six months old. You should use caution when giving Simparica to dogs who are currently pregnant or lactating as its effect on these conditions hasn't been evaluated. Ask your vet before you give your dog any medication.

  6. Do I Need a Prescription to Buy This Medicine?

    Yes, you need a prescription to buy Simparica Flea and Tick Medication. If your dog is getting recurrent tick and flea infestations, then you should speak to your vet about Simparica for dogs. If your dog frequently works in an outdoor environment like a farm, then you can talk to your vet about protecting your dogs using Simparica.

  7. My Dog Is Allergic to Protein. Does Simaprica for Dogs Contain Any Protein or Other Allergens?

    Simparica for dogs contains protein, but it is in the form of hydrolyzed soy protein. This means that it is likely to be safe even for dogs with a protein allergy. This medicine also contains starch, corn, wheat germ, Anhydrous Dibasic Calcium Phosphate, corn syrup, and gelatine. The active ingredient in this medicine is Sarolaner.

  • Zoetis Brand
  • Flea & Tick Pharmacy
  • Dog Pet Type

Is Simparica Better Than Frontline?

Both Simparica for dogs and Frontline are used as flea medicines for dogs, and they are both effective in flea and tick treatment. However, Simparica is not the better flea medicine for dogs when compared to Frontline flea treatment. Simparica kills ticks and fleas, and it is not safe to use this flea and tick medicine on pregnant, lactating, or breeding dogs. On the other hand, not only does Frontline kill fleas and ticks, but it also destroys their eggs and larvae. Hence, Frontline is arguably the best flea treatment for dogs. That being said, Simparica is one of the best dog flea treatments available right now. It can successfully eliminate all adult fleas on dogs. However, it cannot match the standards of Frontline.

Is Simparica Safe?

Yes, Simparica is a safe and effective treatment for fleas as well as ticks in dogs. The drug is approved by the FDA and has been given clearance for prescribed usage. That means you will need a vetโ€™s authorization or prescription for buying this medicine. You also need to maintain certain precautions from your end to ensure the safety of your dog while starting or continuing the Simparica dosage. Do not give this flea treatment drug to dogs that are under six months of age. You must also avoid, or stop giving Simparica to your dogs if they are lactating, breeding, or pregnant. The drug might interfere with these biological processes, which is why it is best to maintain caution. Ask your vet if you can use Frontline flea treatment on your pregnant dog if you must use a flea and tick medication.

Can My Dog Still Get Fleas With Simparica?

Yes, your dog can still get fleas with Simparica. There are mainly two reasons for this. Firstly, it is possible that the fleas came back after the medication wore out. In that case, there is a chance that your house has a flea infestation somewhere, or perhaps your dog was in a flea-infested place. Secondly, since Simparica does not destroy larvae or eggs of fleas and ticks, it is likely that the fleas came from there. This has a higher chance of happening if your dog seldom leaves the house and still has fleas despite the Simparica treatment.

Does Simparica Make Dogs Sick?

Simparica might make your dogs sick, but it is not a common occurrence. The medication can lead to tremors or seizures. This is common in dogs that have a history of neurological disorders, however, it can also happen to those without such history. The drug can also make a dog sick if it is pregnant or breeding. Some of the most adverse side effects of Simparica include vomiting and diarrhea. You should take your dog to the vet if you notice these symptoms. Continuous shaking for a long period also requires urgent medical attention.

Should I Give My Dog Simparica Trio?

You can give your dog Simparica Trio if you need to treat it for both fleas and ticks, as well as worms. However, you will still need a vetโ€™s prescription to be able to use this drug. Simparica Trio cannot be used on dogs that are less than 8 weeks of age.

What Does Simparica Trio Not Cover?

Simparica Trio does not cover anything except ticks, fleas, and worms. It is very effective against these three parasites in dogs and can guarantee proper treatment for them.

Does Simparica Deworm?

Yes, Simparica Trio can deworm. It can work effectively against heartworm and lungworm in dogs. Besides, the medicine can take care of fleas and ticks just as well.


Simparica is for use only in dogs, 6 months of age and older. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. The most frequently reported adverse reactions were vomiting and diarrhea.

Option UPC/SKU
2.8 - 5.5 lbs 3-dose 087219120064

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