At a Glance
Helps older dogs with behavioral problems associated with old age
Manages symptoms associated with Cushing’s Disease
Once a day dosage
This product requires a prescription.
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Selegiline is used to treat Canine Cognitive Dysfunction Syndrome. It can also be used to treat symptoms associated with pituitary-dependent Cushing's Disease in dogs. Selegiline comes in easy-to-administer oral tablets with five different strengths.
Selegiline is a monoamine oxidase inhibitor (MAOI). Usage of selegiline is meant to result in enhanced catecholaminergic nerve function and increased dopamine levels helping dogs with cognitive dysfunction caused by aging.
Side Effects and Warnings
Not meant for dogs with aggression issues.
Possibly side effects include:
Decreased appetite, drooling, vomiting and diarrhea, fatigue, confusion, restlessness, hearing loss, trembling, itching, hair loss, anemia (pale gums). Repetitive behaviors (ex. walking in circles, obsessive interest in something). If your dog suffers an allergic reaction such as hives, swelling of lips, tongue or face or difficulty breathing seek immediate emergency veterinary medical attention and discontinue dosages. Other less serious side effects may occur such as nausea or upset stomach, diarrhea or headache. If these, or any other side effects seem unusualy or bothersome to your animal talk to your veterinarian.
Possible interactions may occur with ephedrine or other MAOI's. Discontinue selegiline at least 14 days prior to starting treatment with some narcotic pain killers (ex. Demerol), phenylpropanolamine, SSRI's (ex. fluoxetine) and tricyclic antidepressants (ex. amitriptyline). Some narcotic pain killers (ex. Demerol), phenypropanolamine, SSRI's (ex. fluoxetine) and tricyclic antidepressants (ex. amitriptyline) should not be used within 5 weeks of administering selegiline.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
5mg, Per Tablet
5mg, Per Capsule
Store in a cool, dry place.
Give your dog the recommended dosage (typically one pill) every morning.
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Rated 4.3 out of 5 by 16
Rated 2 out of 5 by veith507 easy to adminstar
We notice some improvement, still hoping more to come with ordering second order
May 8, 2016
Rated 1 out of 5 by abcdef Didn't seem to make a difference
Didn't seem to make a difference
in the dog
Selegiline is used to treat Canine Cognitive Dysfunction Syndrome. It can also be used to treat symptoms associated with pituitary-dependent Cushings Disease in dogs. Selegiline comes in easy-to-administer oral tablets with five different strengths.Selegiline is a monoamine oxidase inhibitor (MAOI). Usage of selegiline is meant to result in enhanced catecholaminergic nerve function and increased dopamine levels helping dogs with cognitive dysfunction caused by aging.
April 27, 2015
Rated 4 out of 5
by Marydeen Works for my 12 year old Bichon Frise
My Belle has been taking this product for approximately 4 years now. It has definitely extended her life. I am very happy we found this for her.
January 21, 2015
Rated 5 out of 5 by Maeilyn This product is only available for senior dogs
Half the price of my vet...but I was promised free shipping which I didn't get.
November 2, 2014
Rated 4 out of 5 by Vytas4458 Works well!
I use this for my aging dogs when they start to get a little disoriented or show the signs of mental slowing. The medication takes about a week to see the effect but it works great! If you have an older dog that forgets to go outside to urinate or can't remember where the dog door is or stands around looking lost at times, it may be a sign that they need some medication help. I have been using this medication since 2002 when my first old girl started to lose it after she lost her sight, it brought her back to her old self and helped her cope with her disability.
August 15, 2014
Rated 5 out of 5 by breeze59 Really improved quality of life for my old dog.
We used selegiline once for about 6 months when Hunter was 12 - he was having trouble adjusting after the loss of his best dog pal with anxiety and fear of going outdoors or even open spaces indoors. This worked beautifully and he weaned off fine. We started to give it to him again at age 16 for nighttime restlessness and anxiety and it has again worked beautifully for him, he sleeps through the night and has no problem with anxiety. Still seems to have some mild confusion. He will turn 17 in 2 weeks (!) and quality of life is still pretty good. It is quite expensive, but prices on petcarerx make it doable.
May 21, 2014
Rated 5 out of 5 by Vic14k Selegiline Gave my Dog his Personality Back
My 13 year old Lab has dementia. This drug is a miracle. He acts like himself. Before Selegiline, he wasn't eating, forgot how to navigate stairs, barked at walls and furniture, and was generally confused. He's had zero bad side effects.
December 29, 2013
Rated 4 out of 5 by Gertee Helping my 15 yr old Wire Fox Terrier
Started the drug on my vet' recommendation due to my little dog's declining canine cognitive dysfunction. She has been on it a month + now and it has helped. Much less whimpering, waking up in middle of night wandering around . We also started her on special diet. The 2 combined are helping. She is not like her younger self, but less anxious, less stressed and more oriented to time, place.
I highly recommend you try this for your elderly dog with declining cognition. Depending on each dog's condition, the improvements vary for each dog.
For us it has helped, and our dog seems better, but she is not cured of her CDS; others have reported dramatic results. Results are not the same for every dog.
July 18, 2013
Epilepsy & Neural Health
Selegiline is a medicine used to help manage some of those aliments that can occur as dogs get older. It's included in regiments to treat Parkinson's disease, senility, and Cushing's disease.
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based on 16