Nutramax Denosyl Liver and Brain Health Supplement for Dogs and Cats
Refills on File
Your pet {{refill.petName}} has {{refill.refillsRemaining}} refill{{refill.refillsRemaining>1?'s':''}} for ‘{{refill.options}}’ which will expire on {{refill.expiresOn}}.
{{refill.petName}}'s refills for this have expired on {{refill.expiresOn}}
At a Glance
Liver Support: Denosyl features s-adenosylmethionine (SAMe) to support the liver by increasing levels of glutathione, an important antioxidant for liver health and the liver's main detoxifier 
Bioavailability: The SAMe in Denosyl has been proven to be bioavailable, meaning it enters your pet's bloodstream to help support the liver 
Cognitive Support: Research has shown that SAMe may also support cognitive function in dogs and act as a neuroprotector 
From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement 

Nutramax Denosyl Liver and Brain Health Supplement for Dogs and Cats

List Price:
{{list_price * quantity | currency}}
List Price:
{{list_price * quantity | currency}} {{(list_price + 0.01) * quantity | currency}}
List Price:
{{list_price * quantity | currency}}
List Price:
See price in cart Why we cannot show price
List Price: {{list_price * quantity | currency}}
25% OFF w/code: CARE25
PetPlus Price:
{{petplus_price * quantity |currency}}
PetPlus Price:
See price in cart Why we cannot show price
Sale Price:
{{sale_price * quantity|currency}}w/code {{siteCode}}
Your Price:
{{(map_price + 0.01) * quantity | currency}} See price in cart w/code {{siteCode}} Why we cannot show price
Savings:
{{petplus_savings_amount * quantity|currency}} ({{petplus_savings_percent}}%)
Savings:
{{coupon_savings_amount * quantity|currency}} ({{coupon_savings_percent}}%)
Join PetPlus today and get this for {{intro_price_total|currency}} Why we cannot show price
Join PetPlus today and {{use_strict_map_rules?"see price in cart":"get this for a special price"}} Why we cannot show price

inlowout of stock
{{tier1Label}}
{{tier2Label}}
{{customizeLabel}}
{{quantityLabel}}
Get notified as soon as this becomes available
Thank you.
We will email {{notifyEmail}} when this is back in stock.
Recommended Alternatives:
Limit ( {{ selected_sku_data.cartLimit }} ) per customer. Orders for more than this may not be fulfilled.
Shipping is always free with PetPlus | Arrives in 1-3 days on average
Free shipping over $48* | Arrives in 1-3 days on average
Select Autoship options at checkout
At a Glance
Liver Support: Denosyl features s-adenosylmethionine (SAMe) to support the liver by increasing levels of glutathione, an important antioxidant for liver health and the liver's main detoxifier 
Bioavailability: The SAMe in Denosyl has been proven to be bioavailable, meaning it enters your pet's bloodstream to help support the liver 
Cognitive Support: Research has shown that SAMe may also support cognitive function in dogs and act as a neuroprotector 
From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement 

Frequently Bought Together

Total Price

Nutramax Logo

The liver isn't just the largest organ inside your dog's body. It's also one of the most important. Denosyl is a supplement that helps keep your dog's liver healthy. It is often difficult to diagnose liver disease in dogs as symptoms are mild or even non-existent. If your dog is acting weaker than usual, throwing up, maintaining a reduced appetite, or having seizures, they may be fighting a type of liver disease. Talk to your veterinarian about Denosyl and find out what it can do for your pooch.

Denosyl contains SAMe (s-adenosylmethionine) to help support the liver health of cats and dogs and may support brain health in dogs. It is available in enteric-coated tablets for both dogs and cats. Denosyl Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.

  • Nutramax Brand
  • Vitamins & Supplements Pharmacy
  • Care Wellness Philosophy
  • Ivermectin Sensitivity Allergies
  • Non-Prescription Pharmacy Type
  • Nutramax Manufacturer
  • Senior Life Stage
  • Oral Application
  • Cat Pet Type
  • Dog Pet Type

What is Denosyl Used For?
Answer

The organ that helps in the detoxification of the body is the liver. It also helps in synthesizing proteins and the production of bile and other necessary chemicals to smoothen digestion. Therefore, for the well-being of your pet, it is crucial to keep their liver healthy. The toxin removal from the body is possible with the liver itself. The liver heavily depends upon the antioxidant glutathione for toxin filtration. If the glutathione level is low, it might harm cats as well as a dog. If the liver is not functioning with ease, it leads to deterioration of the overall health and can cause seizures, ataxia, and hemolytic anemia. Save your pet from the deficiencies of glutathione. The main aim of Denosyl is to avert glutathione levels going down and make sure proper functioning of the liver. However, the objective of increasing the level of glutathione does not mean adding up too many antioxidants to your dog's diet.

Is Denosyl a Prescription Drug?
Answer

Denosyl is a medicine for the pet that helps in the treatment of the liver. Denosyl is an over-the-counter medicine for cats, dogs, and other animals. There is no prescription needed, but if your vet recommends it is always better. Denosyl is available as 90mg, 225mg, and 425 mg in the form of a stabilized tablet.

Can You Crush Denosyl?
Answer

Denosyl is suitable for all sizes of dogs, whether small, medium, or large. It is recommended not to crush the Denosyl tablet or even break. It is because the dosage enteric cost as well as inhibits absorption gets damaged.

Is Denosyl the Same as Denamarin?
Answer

Denosyl and Denmarin are not the same, the main difference of both the medications is that Denamarin has a second ingredient that is not there in Denosyl. Silybin is the ingredient present in Denamarin that gives more liver support. It helps in promoting a better functioning of the liver in conjunction with SAM-e. It is clear that out of the two medications, Denamarin is a much powerful supplement needed for pets that demands more liver support.

Can a Dog Recover from Liver Damage?
Answer

The liver gets infected by viruses, bacteria, fungi, or parasites. Generally, viral disease related to your dog's liver is transmissible canine hepatitis. It leads to scarring and inflammation. It is a disease that gets prevented with vaccination. Your dog will give you signs of a liver issue. You will notice several symptoms in your dog such as loss of weight, no stability in walking, appetite loss, frequent urination, the color of tongue and eyes turning yellow. The liver is efficient enough to regenerate on its own and build healthy and new cells. But an increasing number of dead tissues often results in cirrhosis and scarring. Most of the symptoms are treatable with the help of medicines that help in the proper function of the liver. A change in diet also reduces the pressure on the liver.

Is Denosyl Safe for Dogs?
Answer

Yes, Denosyl is safe for the dog. It is a nutritional supplement that reduces the number of liver issues like liver disease. Denosyl helps in the hepatic glutathione levels in dogs. Dogs and cats can tolerate Denosyl very well, and it is safe for them to consume.

How Do You Give Denosyl?
Answer

Denosyl is available as chewing tablets, and dogs of all sizes can take it. The tablets need to be given an hour before they feed on an empty stomach. In this way, Denosyl gets well absorbed. There might be some owners who will find difficulty in giving the tablets to their dogs directly. For these kinds of dogs, the best is to mix the tablet in a small diet. Your dog will end up consuming it.

How Long Can a Dog Take Denosyl?
Answer

For clinical health, the dog needs 20 mg per kg per day of Denosyl for a period of one and half months. It never gives any negative effect while taking the tablets of Denosyl, and the dog remains in good health. According to the pharmacokinetic study, when a fasting dog takes Denosyl, the plasma level shoots up, not beyond 4 hours.

What are the Side Effects of Denosyl for Dogs?
Answer

There are few cases of vomiting reported as a side effect of consuming Denosyl. Moreover, the overdose of Denosyl is harmful to your pet. Always be cautious when you give Denosyl with other medicines such as Mitaban Dip, Tramadol, Clomipramine, Fluoxetine, or Amitriptyline.

What Does Denosyl Do for Dogs?
Answer

Denosyl helps in the protection of liver cells from dying by repairing and regenerating the cells. Of course, Denosyl supports the dogโ€™s liver. According to research, the SAMe in Denosyl also supports intellectual function in canines.

S-Adenosylmethionine

Vomiting is a rare side effect. If you are uncertain whether your dog would benefit from a liver medication like Denosyl, please consult a pet specialist or veterinarian.

Store in a cool dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

For dogs up to 12 lbs, 1 tablet per day. For cats up to 12 lbs, 1 tablet per day; for cats over 12 lbs one tablet twice daily. Tablets should be given on an empty stomach for optimal absorption. They may be given at least two hours after a meal or one hour before a meal.

Store in a cool dry place not to exceed 86ยฐ F. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Nutramax Denosyl Liver and Brain Health Supplement for Dogs and Cats is manufactured by Nutramax
Option UPC/SKU
Cats and Small Dog up to 12 Lbs - 90mg / 30 stabilized tabs 755970617658
Large Dogs Over 35lbs - 425mg / 30 stabilized tablets 755970614305

Related/Top Articles

Lifespan of a Dog: A Dog Years Chart by Breed

How Long Should You Expect Your Dog to Live?

Read More
Caring For A Sick Dog: The Dos (And The Dont's)

How To Make Your Dog Feel Better, Not Worse

Read More
Proviable Probiotic

Supporting Your Pet's Digestive Health

Read More

Customer Reviews

Rating Summary 17 review(s)
5 stars
13
4 stars
3
3 stars
0
2 stars
1
1 star
0
5 / 5
* = required

New Product Review


Uploaded Image 1
Uploaded Image 2
Uploaded Image 3
  • {{error}}
SUBMIT REVIEW
Showing 1 - {{visible_reviews.length}} of {{total_reviews}}

This product has no reviews yet. Write a review.

M
Excellent
VERIFIED PURCHASER

I got my order in a timely manner.

Monica Waldron Stevens recommends this item.
Was this review helpful? 0 0

L
Caused diarrhea
VERIFIED PURCHASER

Although this did lower my pup's liver enzymes it caused diarrhea, which isn't listed as a side effect.

Linda recommends this item.
Was this review helpful? 0 0

K
Great Supplement
VERIFIED PURCHASER

Our current vet suggested my little guy take Denosyl because he had a particular liver value that had been out of whack for a couple of years and was getting worse with each testing. At the time I am writing this review, Riley has been on this supplement for about 3 years and has not seen any significantly bad change in that liver value since. So yes! This supplement does work! If your vet suggests it, I urge you to seriously think about giving it to your pet. It may be just the thing your pet needs to help him live a healthier, happier and, most importantly, longer life with you.

Kat L. recommends this item.
Was this review helpful? 1 0

K
Great product
VERIFIED PURCHASER

We've been using this product almost daily since our senior schnauzer was diagnosed with liver problems several years ago. It's the single treatment that has been recommended by multiple vets. The result has been a gradual improvement in the values of the blood tests used to monitor his liver and for him it's a daily treat he enjoys. That's a win-win in my book.

katphile recommends this item.
Was this review helpful? 1 0

B
We think it's working
VERIFIED PURCHASER

So far, so good. Though difficult to "trick" our Schi-tzu into swallowing the pill, it seems to be working. Chester's latest reading by the vet indicates progress and improvement in our dog's liver problem.

bjedit recommends this item.
Was this review helpful? 1 0

L
This pill easier take than others.
VERIFIED PURCHASER

Breeze ordering and delivery to my house!!! Good value too!!

Lana021449 recommends this item.
Was this review helpful? 0 0

I
Great savings compared to vet prices
VERIFIED PURCHASER

I took my senior dog in for dental cleaning in Feb 2014. The vet performed preliminary blood work where is was found her liver levels were elevated and they would not be able to put her under for the teeth cleaning. We immediately started her on Denosyl, liver food (wet and dry). She would not eat the wet food. No matter what I tried. I can't say for sure that this medicine is helping her (she's doing o.k.) but I do know if I had been purchasing it thru PetCareRx for the last five months it would have saved me tons of money every month instead of purchasing it at the vet. Supposedly this vet is a low cost clinic.

imagypsy recommends this item.
Was this review helpful? 1 0

R
Great for Rabbits Too

My 9 1/2 year old rabbit has liver problems from Anesthesia when he needed his teeth trimmed. The vet said to try this and it has helped! I thought I would try online as it is cheaper. Sorry vet! : )

Rabbit_Lover recommends this item.
Was this review helpful? 0 0

O
Cat with seizures

My cat has occasional seizures and needs to take phenobarbital, which puts a strain on her liver. The Denosyl helps her liver to function properly and works great. She has not had any seizures in a long time.

Owner_of_a_4_yr_old_cat_with_seizures recommends this item.
Was this review helpful? 0 0

M
Anything To Keep Our Little Man Going!

Our 10 year old Boston Terrier, Peatie, has had many health challenges in the past year: thyroid issues, seizures, liver issues. At one point about 4 months ago our vet recommended Denosyl because his bile acid tests indicated his liver wasn't functioning well. We purchased his first pack from the vet and almost fell out of the chair at the price. I immediately started searching online for other purchasing options and came across PetCareRx. Great price, fast delivery. As for Mr. Peatie, he's doing good.

Margaret_Proud_owner_of_a_great_senior_Boston_Te recommends this item.
Was this review helpful? 0 0

M
Anything To Keep Our Little Man Going!

Our 10 year old Boston Terrier, Peatie, has had many health challenges in the past year: thyroid issues, seizures, liver issues. At one point about 4 months ago our vet recommended Denosyl because his bile acid tests indicated his liver wasn't functioning well. We purchased his first pack from the vet and almost fell out of the chair at the price. I immediately started searching online for other purchasing options and came across PetCareRx. Great price, fast delivery. As for Mr. Peatie, he's doing good.

Margaret_Proud_owner_of_a_great_senior_Boston_Te recommends this item.
Was this review helpful? 0 0

P
Review of Denosyl purchase

The product was easy to find on your web site and was identical to that supplied by my veterinary practice. The shipment was well packaged and was received in good time.

Peggy_owner_of_a_senior_sheltie recommends this item.
Was this review helpful? 0 0

A
Denosyl for diabetic dachshund

Our Dachshund has had back surgery and now he has diabetes. He's been on Denosyl for 2 yrs. and it keeps him healthier and happier, it's a daily part of his day.

Anonymous Pet Parent recommends this item.
Was this review helpful? 0 0

R
notice difference immediately

our dogs breath improved right away after we started giving him denosyl

Randimultipoo_owner recommends this item.
Was this review helpful? 0 0

A
Recommended by vet

Our 14 year old beagle has shown great improvement since beginning use of this product 8 months ago.

Anonymous Pet Parent recommends this item.
Was this review helpful? 0 0

O
Good product!

First heard of from a friend. Poor liver function in 6 year old dog. Low fat diet plus this product and liver readings good.Have used @year.

Owned_by_2_small_dogs_and_a_cat recommends this item.
Was this review helpful? 0 0

K
first rec'd this from our vet

Use off and on throughout the year, has kept our 14 1/2 year old cat alive,and in good health

Kathy_cat_owner_elderly_cat recommends this item.
Was this review helpful? 0 0

Page 1 of 1 1