At a Glance
Manages urinary incontinence in dogs and cats
Helps to reduce accidents
Available in liver flavored chewable tablets
Our regular price:
This item is on sale!
- Wholesale prices on Flea & Tick, Heartworm, Supplements, & Rx Food
- Wholesale prices on all Prescription Medication
- Free shipping on all PetPlus items
- 20% off all other products on PetCareRx.com
- 24/7 Vet Helpline - Call, Email, Chat
- 100% Member Savings Guarantee
- Only $50/year (per pet, plus tax)That's UNDER $5 per month!
Learn More »
Proin is a prescription, liver-flavored chewable tablet, intended to manage urinary incontinence in dogs and cats, by constricting and strengthening the urinary sphincter. Proin is a supplemental adrenergic agent, which means it mimics adrenaline or epinephrine, which are the hormones needed to trigger vasoconstriction, the constriction of blood vessels.
Proin also maintains balanced phenylpropanolamine levels, helping to prevent the negative side effects associated with high levels, including heightened blood pressure, and hyperexciteability. Proin is a classified controlled substance in Arkansas, Iowa, Illinois, Louisiana and Oregon.
Side Effects and Warnings
Keep out of reach of children.
Do not give with ephedrine or epinephrine, or within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Proin may cause restlessness and hyperactivity, pale gums, difficulty urinating, irritability, hypertension, and decreased appetite. Hypertension risk increases if Proin is given concurrently with non-steroidal anti-inflammatory drugs (NSAIDs), or with reserpine, tricyclic antidepressants, amitraz (the active ingredient of the Preventic tick control collar and canine Promeris, a flea control product), or ganglionic blocking agents. Conditions such as glaucoma, prostatic hypertrophy, hypertension, hyperthyroidism, diabetes mellitus, and cardiovascular disorders, may worsen.
Side effects may worsen if used in conjunction with other sympathomimetic drugs such as ephedrine or epinephrine. Notify your veterinarian of any medications, treatments or vitamins your dog is taking, prior to administering Proin.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
25mg per chewable tablet
50mg per chewable tablet
75mg per chewable tablet
Store at room temperature away from moisture and heat.
Administer Proin chewable tablets, to the exact specifications of your veterinarian, and with food.
||Tablets: The usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Drops: 0.4-0.8mg/pound every 12 hours.
Rated 4.8 out of 5 by 53
Rated 4 out of 5
by Phil55 Seems to work 90% of time.
Cut rate of accidents on my female GS. although she sometimes still leaks on a cold floor. Definitely improved her condition although not 100%.
November 3, 2015
Rated 5 out of 5 by Mousie Pup incontinence
I got a pup from a rescue at 3 mos old and she was already spayed. She always had a leaking problem, and most times as she grew, she would gt up and be in a pool of urine. I had her checked by 2 specialists and my regular vet, and all said it likely be a lifelong issue, maybe due to early spaying and lack of estrogen production. I have been giving her this RX for 2+ years, and it basically has correctd the issue. Rarely, doees she have a problem, unless I forgt to give her her meds.
October 12, 2015
Rated 5 out of 5 by gardengirlretired Proin has been a lifesaver to help my senior dog Ally.
Proin has helped my just turned 15 year old senior dog Ally. The medicine has worked controlling her incontinence for the past 2-3 years and my Vet recommended it.
September 6, 2015
Rated 5 out of 5 by rjdelisi It does what it's supposed to do
Hard to write a review of a drug except to say that it works....it definitely controls my Husky's incontinence with no side effects. She takes the pill willingly, so we're all happy.
September 1, 2015
Rated 4 out of 5 by BoxersRule Effective From The Very First Dose!
I have a 9 year old boxer. It's common in female dogs to become incontinent as they age. My vet prescribed Proin. From the very first dose, we have not had one single episode. This stuff really works!!
April 3, 2015
Rated 4 out of 5 by cooch working well
Product works well. Only few isolated incidents. Would strongly recommend.
March 9, 2015
Rated 5 out of 5 by Weschie Great drug
This drug is amazing. it took a few days to be effective but my female, 10 year old dog has had no accidents since. No side effects. She doesn't like the taste so I have to be creative but this drug is a God-send!
January 1, 2015
Rated 5 out of 5 by lizle Excellent Product
We have tried over the counter bladder aids at PetCo and they do not work. This drug, Proin works. My dog hates the taste that is the only disadvantage but when I get it down her, it works.
November 9, 2014
In stock! Order now!
based on 53
As a Complete Care Plan member, enjoy the following benefits:
- All of your pet prescriptions at wholesale pricing
- Save 25% every time you go to the vet (through PetAssure)
- Convenient pickup at over 60,000 local pharmacies, including CVS, Target, Walgreens, and Walmart
- 20% off everything at PetCareRx.com
- $50 off your first dog sitter booking with Rover.com
- Guaranteed savings in your first year as a member
- And much more...
All this for only $9.99/month
Would you like to upgrade?
Add at Regular Price