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Piroxicam is a non-steroidal anti-inflammatory drug (NSAIDs) that is commonly used for managing pain and inflammation in dogs. The action mechanism of Piroxicam is to hinder the secretion of prostaglandins, thereby bringing relief from fever, pain and inflammation. It could also be combined with other drugs in the treatment of transitional cell carcinoma- a type of bladder cancer in dogs.
Desist from using Piroxicam in animals that are allergic to this drug, and in those with a noted history of bleeding, intestinal inflammation and high blood pressure. Use extreme caution while administering this medication in pets with heart ailments. Some medicines such as diuretics or ACE-inhibitors could have serious interactions with Piroxicam. So, make sure to verify that the medications administered to the pet do not belong to any of these groups. Piroxicam, when used along with corticosteroids is found to enhance the risks of ulcers.
Piroxicam is available in 10 mg and 20 mg capsules. The dosage might differ according to the condition for which it is used, and the response to the treatment. Normally for anti-inflammatory effect, piroxicam is dosed at 0.15 mg per pound (0.3 mg/kg) every 48 hours, while a daily dose of 0.15 mg per pound (0.3 mg/kg) might be required to manage transitional cell carcinoma.
Clinical results have proved that this drug is well tolerated by dogs, even though side effects might occur in rare cases. Stomach and intestinal ulcers, bleeding, dark stools, peritonitis, vomiting etc., are some of the common side effects. A few of these could be life threatening as well. Piroxicam can hamper the smooth functioning of kidneys which might lead to papillary necrosis. Piroxicam could also damage the natural blood clotting mechanism, thereby increasing the risks of bleeding.
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