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At a Glance
FDA-approved medication for dogs and cats.
Prevents and controls four dangerous and potentially fatal internal parasites.
Protects pets from heartworms, roundworms, whipworms, and hookworms.
Parasiticide milbemycin oxime paralyzes and removes gastrointestinal parasites.


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Generic available: Milbemycin Oxime
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At a Glance
FDA-approved medication for dogs and cats.
Prevents and controls four dangerous and potentially fatal internal parasites.
Protects pets from heartworms, roundworms, whipworms, and hookworms.
Parasiticide milbemycin oxime paralyzes and removes gastrointestinal parasites.


Ultimate Guide to Interceptor

Meet the Dangerous Parasite Protector: Interceptor!

Interceptor is an FDA-approved dog and cat medication that protects your dogs from four dangerous (and potentially fatal) internal parasites: heartworms, roundworms, whipworms, and hookworms. Interceptor is a monthly, oral tablet that ensures that your dog or cat is safe, happy, and healthy.

How does the medication Interceptor work?

Interceptor is a medication with one powerful active ingredient Milbemycin Oxime, which is the brand Interceptor 's generic name.

Milbemycin Oxime is a strong parasiticide and a 100% effective heartworm disease preventative against D.immitis (i.e., heartworm larvae). Additionally, Milbemycin Oxime controls the other three dangerous intestinal worms that are found in dogs (i.e., adult roundworms, hookworms, and whipworms).

Milbemycin Oxime is part of the avermectin category of drugs and pesticides that intercepts the major neurotransmitter in the nervous systems of all vertebrates. Certain receptors are targeted during its deworming that then causes parasite paralysis and eventually death of nematodes (i.e., roundworms) and arthropods (e.g., insects).

How is Interceptor administered?

Interceptor is administered orally once a month and protects a dog for the next 30 days. These artificial beef-flavored tablets are easily taken and consumed by 95% of dogs. See the monthly dosage chart below that depends on your dog or cat 's body weight:

Body Weight of Dog (D) or Cat (C)

Monthly Dosage of Milbemycin Oxime (mg)

No. of Tablets

D 2 - 10 lbs.

2.3 (Brown)


D 11 - 25 lbs.

5.75 (Green)


D 26 - 50 lbs. C 6.1 - 12 lbs.

11.5 (Yellow)


D 51 - 100 lbs. C 12 - 25 lbs.

23.0 (White)


D 100+ lbs. C 25+ lbs.

Give a combination of tabs, based on weight

What are the potential side effects of which you should be aware?

Test for heartworm disease before using Interceptor.In a small percentage of milbemycin-treated dogs, digestive and neurologic side effects may occur. Interceptor 's rare unfavorable reported reactions are vomiting, diarrhea, depression, lethargy, hypersalivation, seizures, weakness, and decreased appetite.

Frequently Asked Questions
  1. Does Interceptor work differently for cats versus dogs?

    For dogs, Interceptor treats heartworm disease and hookworms, and removes and controls whipworms and roundworms. For cats, Interceptor is the only monthly, oral medication that guards against heartworms and eradicates adult roundworms and adult hookworms.

  2. What is Interceptor?

    Interceptor is a prescription drug that comes as a monthly, oral tablet that protects dogs and cats from four dangerous (and potentially fatal) internal parasites. Interceptor prevents heartworm disease, controls adult hookworms, and removes roundworms and whipworms. Interceptor only affects internal, not external, parasites.

  3. What is the difference between Interceptor, Interceptor Plus, and Interceptor Spectrum?

    Interceptor Plus (U.S.) and Spectrum (Australia) also have the active ingredient praziquantel, an anthelmintic natural substance that kills trematodes (i.e., tapeworms) and cestodes (i.e., flukes). Praziquantel is an insect growth regulator (IGR) that inhibits flea larvae from hatching or growing into an adult flea.

  4. What are Interceptors ' flavors?

    Interceptor is a beef-flavored vitamin-like tablet, not chewable. You can give the tablet by hand, hide it in something like cheese, or crush it into the pet 's food. Interceptor Plus and Interceptor Spectrum are a chicken-flavored chewable.

  5. How long does it take for Interceptor to work?

    This medication should take effect within one to two days to create a layer of protection against internal parasites. If you see intestinal parasites or worms in your pet 's stool, it means that the medication is working, because it is clearing out the pet 's gastrointestinal system.

  6. What is the Interceptor dosage for small, medium, and large dogs & cats?

    Before purchasing Interceptor, make sure that you test your pet for heartworm disease before deworming therapy and before using Interceptor.Interceptor has five different options (and boxes) of milbemycin oxime dosages (mg) based on your cat or dog 's body weight. See the monthly dosage chart above.

  7. Is Interceptor for puppies and kittens?

    Interceptor can be given to puppies that are at least 4 weeks of age and weighing 2 lbs. Interceptor can be given to kittens that are at least 6 weeks of age and weighing 1.5 lbs.

  8. What do the Interceptor reviews say?

    Interceptor reviews rate 5 out of 5 stars. Most reviewers say that Interceptor is a new product that tastes and works great, even for their sensitive pets.

Concluding Thoughts

The most important thing that you should know about Interceptor is its power to protect your dog and/or cat from dangerous (and potentially fatal) intestinal parasites. Interceptor ensures that your pets will be safe from heartworms (and heartworm disease), roundworms, whipworms, and hookworms, and the infections that they cause.

DISCLAIMER: FDA law restricts Interceptor only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if it 's a good idea to treat all of the animals in your household to control intestinal parasites.

  • Elanco Animal Health Brand
  • Heartworm & Deworming Pharmacy
  • Elanco Animal Health Manufacturer
  • Oral Application
  • Cat Pet Type
  • Dog Pet Type

Is Interceptor a Good Heartworm Medicine?

Yes, Interceptor heartworm medicine is one of the best out there on the market. By giving your dog Interceptor heartworm medication, you are protecting him or her not only from heartworm but also several other kinds of worms. This is because Interceptor also treats roundworm, whipworm, and hookworm infections.

Is the Interceptor Available?

Interceptor is available in two different formulations - Interceptor and Interceptor Plus. The difference between Interceptor and Interceptor Plus is that Interceptor Plus also treats tapeworm infections. However, you cannot use Interceptor Plus in puppies younger than 6 weeks of age.On the other hand, you can use Interceptor with puppies who are 4 weeks old. Interceptor is also available in different dosages for dogs of various sizes. The brown box is for dogs between 2-10 lbs and contains 2.3mg milbemycin oxime per tablet. The green box is for dogs between 11-25 lbs and cats between 1.5-6 lbs. Each pill in the green box contains 5.75mg of milbemycin oxime. The yellow box is for dogs between 25-50 lbs and cats between 6.1-12 lbs and has 1.5mg milbemycin oxime per tablet. Finally, the white box is for dogs between 51-100 lbs and cats between 12.1-25 lbs and contains 23 mg milbemycin oxime.

Do You Need a Prescription for Interceptor for Dogs?

Yes, you need a prescription to buy Interceptor for dogs. Your vet needs to test for heartworm and have a result on your dog's file for you to be able to be prescribed heartworm medication. This is because if your dog has adult heartworms, they could have a severe adverse reaction to this medicine. You should ask your vet to test your dog at least once every year to keep your dog safe and protected from heartworms.

Can Interceptor Make My Dog Sick?

Like any medication, Interceptor does come with a few side effects. They include ataxia, weakness, anorexia, lethargy, convulsions, vomiting, diarrhea, and hypersalivation. You should contact your vet immediately if you notice that your dog is developing or has developed these side effects.

Can I Cut Interceptor in Half?

You should not cut Interceptor pills in half. This is because the medication might not be evenly distributed throughout the medicine but concentrated in the middle. This is done to encourage pets to have this medicine and not have bad taste in their mouths. Interceptor is available in different formulations for different sizes of dogs. Your vet will guide you on which one to purchase for your dog.

Which Is Better Trifexis or Interceptor?

Trifexis and Interceptor have different use cases, so they cannot be compared to each other. Trifexis is designed to target fleas along with heartworm. Interceptor, on the other hand, is designed to treat a wide variety of worms only. If your dog doesn't need treatment for fleas, then using Trifexis would be wasteful. Additionally, flea medication takes a toll on your dog's body. If your dog needs treatment for just worms and not fleas, you should stick to Interceptor.

How Quickly Does Interceptor Work?

Interceptor is a parasiticide that works for internal parasites. It should take a day or two to work. It prevents heartworm disease but not tapeworm infections in dogs and puppies. Note that it works best on young heartworms. It targets the worms' central nervous system and disables it, destroying the worms. Another thing to note is that the main ingredient of Interceptor, milbemycin, is not effective against adult heartworms.

Can My Dog Get Worms While on Interceptor?

The lifecycle of different worms works differently. For example, hookworms need to be treated again 2 weeks after the initial anti-parasitic dose to eliminate all traces of them. Thus, you should speak to your vet about preventatives if your dog gets recurring worm infections.

How Often Should a Dog Take Interceptor?

You should give your dog a chewable Interceptor tablet every month. There are stickers included in the package that you can use to mark your calendar to show the days your dog received this medicine. This also helps you keep track of whether you gave them their medication monthly.

What Happens if My Dog Ate 2 Heartworm Pills?

Interceptor is a sensitive medication. It has side effects and can cause reactions that are harmful to your pet. You should take as many precautions as you can to prevent overdosing on your dog. In case this happens, you need to contact your veterinarian immediately.

Milbemycin Oxime

Side effects are rare, but can include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.

Dogs and pups 4 weeks and older

Weight / Dosage:
  • 2-10 Lbs / 1 Flavor Tab monthly (Brown Box)

  • 11-25 Lbs / 1 Flavor Tab monthly (Green Box)

  • 26-50 Lbs / 1 Flavor Tab monthly (Yellow Box)

  • 51-100 Lbs / 1 Flavor Tab monthly (White Box)

  • Over 100 Lbs / Give combination of Flavor Tabs based on weight
  • Cats and kittens 6 weeks and older

    Weight / Dosage:
  • 6.1-12 Lbs / 1 Flavor Tab monthly (Yellow Box)

  • 12.1-25 / 1 Flavor Tab monthly (White Box)

  • Over 25 pounds / Give combination of Flavor Tabs based on weight
  • Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

    This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

    Interceptor is manufactured by Elanco Animal Health
    Option UPC/SKU
    BROWN,Dogs 2-10lbs. 6 Month Supply 716688201119
    GREEN,Dogs 11-25lbs / Cats 1.5-6lbs. 6 Month Supply 716688201218
    YELLOW,Dogs 26-50lbs / Cats 6.1-12lbs. 6 Month Supply 716688201317
    WHITE,Dogs 51-100lbs / Cats 12.1-25lbs. 6 Month Supply 716688201416
    BROWN, Dogs 2-10 lbs. 12 Month Supply 716688241115
    GREEN, Dogs 11-25lbs / Cats 1.5-6lbs. 12 Month Supply 716688241214
    YELLOW, Dogs 26-50lbs / Cats 6.1-12lbs. 12 Month Supply 716688241313
    WHITE, Dogs 51-100lbs / Cats 12.1-25lbs. 12 Month Supply 716688241412

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