Cimetidine Tablets
Cimetidine Tablets
Click to zoom Tap and hold to zoom
Refills on File
Your pet {{refill.petName}} has {{refill.refillsRemaining}} refill{{refill.refillsRemaining>1?'s':''}} for ‘{{refill.options}}’ which will expire on {{refill.expiresOn}}.
{{refill.petName}}'s refills for this have expired on {{refill.expiresOn}}
At a Glance
Treats and prevents ulcers
Can be used as an antihistamine
Manages acid reflux

Cimetidine Tablets

List Price:
{{list_price * quantity | currency}}
List Price:
{{list_price * quantity | currency}} {{(list_price + 0.01) * quantity | currency}}
List Price:
{{list_price * quantity | currency}}
List Price:
See price in cart Why we cannot show price
List Price: {{list_price * quantity | currency}}
25% OFF w/code: CARE25
PetPlus Price:
{{petplus_price * quantity |currency}}
PetPlus Price:
See price in cart Why we cannot show price
Sale Price:
{{sale_price * quantity|currency}}w/code {{siteCode}}
Your Price:
{{(map_price + 0.01) * quantity | currency}} See price in cart w/code {{siteCode}} Why we cannot show price
{{petplus_savings_amount * quantity|currency}} ({{petplus_savings_percent}}%)
{{coupon_savings_amount * quantity|currency}} ({{coupon_savings_percent}}%)
Join PetPlus today and get this for {{intro_price_total|currency}} Why we cannot show price
Join PetPlus today and {{use_strict_map_rules?"see price in cart":"get this for a special price"}} Why we cannot show price

inlowout of stock
Get notified as soon as this becomes available
Thank you.
We will email {{notifyEmail}} when this is back in stock.
Recommended Alternatives:
Limit ( {{ selected_sku_data.cartLimit }} ) per customer. Orders for more than this may not be fulfilled.
Shipping is always free with PetPlus | Arrives in 1-3 days on average
Free shipping over $48* | Arrives in 1-3 days on average
Select Autoship options at checkout
At a Glance
Treats and prevents ulcers
Can be used as an antihistamine
Manages acid reflux

Frequently Bought Together

Total Price

Cimetidine is a supplement used for dogs and cats to treat and prevent certain inflammations in the stomach lining, such as ulcers, acid reflux, and gastritis. Cimetidine is also an over-the-counter histamine2 blocker utilized to diminish acid production within the gastrointestinal tract.

  • Usage -This medication is employed in pets to address a spectrum of gastric issues, including stomach or intestinal ulcers, inflammation, erosion due to kidney disease, stress-related stomach disorders, adverse drug reactions, acid reflux, and esophageal inflammation.

  • Off-label Use -In veterinary medicine, cimetidine is also prescribed for use in cats, dogs, small mammals, and horses to manage stomach acid disorders. However, its use in these animals should always be under the guidance of a veterinarian.

  • Administration -Cimetidine is typically administered orally in both tablet and liquid forms. Administering the medication approximately 30 minutes before a meal is generally recommended.

  • Missed Dose -In the event of a missed dose, it is advisable to administer the medication as soon as it is remembered. However, if the next scheduled dose is imminent, skipping the missed dose and resuming the regular dosing schedule is best.

  • Side Effects -While side effects from cimetidine are uncommon, they may include confusion and headache. In cats, drooling due to the taste of the medication is possible.

  • Duration of Effect -The effects of cimetidine are typically short-acting and should subside within 24 hours. However, in pets with pre-existing liver or kidney disease, the duration of its effects may be prolonged.

  • Risk Factors -Cimetidine should be avoided in allergic pets or those with liver or kidney dysfunction. Caution is advised when administering to geriatric, pregnant, or lactating pets.

  • Drug Interactions -Cimetidine may interact with a range of medications, so it is important to use it cautiously and disclose all other medications your pet is taking to the veterinarian. Additionally, it may interfere with certain laboratory tests.

  • Monitoring -While no specific monitoring is required, veterinarians may assess the effectiveness of cimetidine in managing the pet's condition during follow-up visits.

  • Storage -Tablets should be stored at room temperature and protected from light and moisture, as instructed. Liquid forms should also be stored according to the manufacturer's recommendations.

In the event of a suspected overdose or adverse reaction to cimetidine, immediate veterinary attention is required.

  • Gastrointestinal Pharmacy
  • Liquid Application
  • Oral Application
  • Cat Pet Type
  • Dog Pet Type

What Is Cimetidine Used to Treat?

Dogs and cats can develop inflammation in their stomachs, leading to gastritis. Sometimes, a licensed vet prescribes cimetidine tablets as a supplement to treat such stomach lining discomfort. You can use this medication to treat abomasal inflammation, gastric ulcers, and duodenal ulcers in your pets. This medication can also protect the esophagus from inflammation, making cimetidine tablets a good treatment option for acid reflux. Cimetidine therapy is beneficial for uremic dogs and cats as it can suppress the immunoreactive parathyroid hormone. These pills can also block neurotransmitter histamines that trigger inflammatory responses. Hence, you can give your pets cimetidine as an antihistamine medication for stomach ulcers after consulting the vet.

Is Cimetidine an Antibiotic?

Emil Syska, a former medical director at Terrace Healthcare Center, says that cimetidine is an H2 (histamine-2) receptor antagonist. That means this class of medication works by blocking the H2 receptors in a dogโ€™s or catโ€™s stomach. Hence, cimetidine is not an antibiotic. Instead, itโ€™s an extra-label drug used as a gastric acid-reducer supplement for your pets. Licensed vets prescribe this drug as a short-term treatment option for ulcers, gastritis, and acid reflux. Since cimetidine isnโ€™t an antibiotic, vets use it as an anti-ulcer medication to keep stomach health in check in a dog or cat. These pills can also help prevent mast cell tumors in your pet.

Is Cimetidine Safe for Cats and Dogs?

Long-term treatment with cimetidine has been proven to reduce vomiting among dogs with chronic gastritis. Moreover, regular use can reduce the buildup of excess stomach acid. Even though cimetidine is well-tolerated by most dogs, cats might develop serious side effects. According to Mark Thirkell, a veterinarian since 1986, cats metabolize drugs in a different manner than other species. Usually, cimetidine acts as an antacid in cats while being an anti-nausea drug for dogs. Only a licensed vet will determine if your cat can digest or if itโ€™s safe to give them this acid-reducer.

How Long Does It Take for Cimetidine to Work?

You can buy this medication either in tablet, injectable, or liquid form. For cimetidine to work for your cats and dogs, you need to administer it in the prescribed quantity. The normal dosage is 3 to 5 mg per pound, depending on your petโ€™s age, symptoms, and weight. Once put on this medication, you must give your pet one dosage every six to eight hours. Remember to give the medicine 30 minutes before a meal, two to four times a day. When administered correctly, the effects of cimetidine can be seen within one to two hours. However, as compared to other acid-reducing drugs, cimetidine is less effective in animals. It takes longer to work, and the effects donโ€™t last long, requiring more doses per day. Even then, completing the course is crucial to avoid relapse and treat any stomach conditions.

Are There Any Side Effects of Cimetidine?

Even though cimetidine is a fairly safe drug to give your pets under vet supervision, some might develop side effects. Hence, you should ensure that your pet isnโ€™t hypersensitive to antihistamines or anti-inflammatory drugs before administering cimetidine. It can lead your pets to develop labored breathing, respiratory failures, and tachycardia. Treating and administering this drug to older pets should be done with caution and supervision. This medication can also interact with other drugs, like sucralfate, diazepam, antacids, digoxin, and metoclopramide. Hence, vets recommend a consultation before administering this drug to pets with blood diseases. If administered without proper caution, cimetidine might also cause your pet to develop heartbeat irregularities, confusion, and allergic reactions.

Is Cimetidine Banned?

No, cimetidine isnโ€™t banned. You can buy this medication as an over-the-counter drug if youโ€™ve got a prescription from a reputed and licensed vet. Some people confuse cimetidine tablets with Zantac, which was also used to treat ulcers in a catโ€™s or dogโ€™s small intestines. The FDA discontinued the use of Zantac because it had impurities that caused health complications like cancer. As a precaution, researchers tested a wide range of anti-ulcer drugs for pets to ensure their effectiveness. Cimetidine was one of those medications, and the FDA didnโ€™t find any impurities in these tablets. While cimetidine is safe for human use, the FDA hasnโ€™t approved its use as a veterinary medication. Even then, vets consider it safe and legal to use cimetidine under regulation and supervision to treat an animalโ€™s intestinal discomfort. The vet will only recommend this compounded formulation if other FDA-approved medications arenโ€™t working for your pet or theyโ€™re allergic to the ingredients.


Cimetidine is an anti-ulcer drug belonging to the category of the histamine receptor- 2, (H-2) blocker. Though Cimetidine is not approved for use in animals, it could be legally prescribed by veterinarians as an extra-label drug. Cimetidine is used in dogs and cats to treat mast cell tumors, gastritis (inflammation of the stomach), esophagitis (inflammation of the esophagus), and gastric or esophageal reflux.Chronic cimetidine therapy is found to be beneficial for uremic dogs under hemodialysis, to suppress the circulating concentrations of immuno reactive parathyroid hormone. Cimetidine has a shorter action span than many other H2 blockers.ย 

Serious side effects are generally not prevalent; however contact the veterinarian if the animal develops labored breathing or rapid heartbeat during the course of treatment with cimetidine. Cimetidine overdosage might result in tachycardia and respiratory failure, and should these symptoms persist, respiratory support and beta-adrenergic blockers should be used.ย 

Adverse effects appear to be very rare in animals at the dosages generally used. May alter the metabolic rates of certain dogs.

Cimetidine should be used with caution in geriatric animals, or those with blood abnormalities or liver or kidney disease. If your pet displays increased heart rate or has difficulty breathing after being administered Cimetidine, consult a veterinarian immediately.

Cimetidine is available in 100 mg, 150 mg, 200 mg and 300 mg tablets; liquid form of 300mg per 5ml and injectable form. The normal dose is 3 to 5 mg per pound, administered orally every six to eight hours. The dosage could be changed depending on the specific condition to be treated. Make sure to complete the course to prevent relapse.ย 

Store in a tight, light-resistant, childproof container at room temperature. Do not refrigerate the injectable product as precipitation may occur.

Option UPC/SKU
300MG/5ml, 8oz, Oral Solution 350383050087

How to Order Prescriptions Online

1. Find the Right Product

Make sure it matches your pets prescription. Donโ€™t forget to compare the dosage for pills/capsules!

2. Add to Cart

Just like any other online store. Make sure the quantity matches whatโ€™s been prescribed by your vetinarian.

3. Tell Us About Your Pet and Vet

Answer some questions during checkout and weโ€™ll contact your vet and verify the prescription for you. You can also mail us the written prescription.

4. Thatโ€™s It!

If the prescription has any refills, processing your future orders for that medication can be expedited.

Related/Top Articles

Why Is My Dog Vomiting Blood?

Read Before You Panic.

Read More
Caring For A Sick Dog: The Dos (And The Dont's)

How To Make Your Dog Feel Better, Not Worse

Read More
Using Glipizide 5 mg to Treat Diabetic Cats

Glipizide 5 mg Normalizes Blood Sugar Levels in Cats with Type II Diabetes

Read More

Customer Reviews

Rating Summary 1 review(s)
5 stars
4 stars
3 stars
2 stars
1 star
5 / 5
* = required

New Product Review

Uploaded Image 1
Uploaded Image 2
Uploaded Image 3
  • {{error}}
Showing 1 - {{visible_reviews.length}} of {{total_reviews}}

This product has no reviews yet. Write a review.

Digestive tract no longer causes discomfort

This is the only medicine tried for the dogs discomfort but it works so well!

Anonymous Pet Parent recommends this item.
Was this review helpful? 0 0

Page 1 of 1 1