How To Crossbreed Dogs For Healthy Hybrids? Have A Plan For A Healthy Litter

How To Crossbreed Dogs For Healthy Hybrids?

Thumbnail of ProZinc Insulin U-40 for Dogs and Cats

ProZinc Insulin U-40 for Dogs and Cats

Diabetes & Metabolic Care
{{petcare_price|currency}} Price in Cart w/PetPlus {{petplus_price|currency}} See PetPlus Price in Cart

There are plenty of reasons why someone might want to crossbreed their dogs; for a unique look or for combined traits from two different breeds that complement each other well. But it's imperative to be careful while crossbreeding to have healthy offspring.

According to the 2021-2022 APPA Survey, around 54% of pet dogs are mixed breeds. While some breeds are better known for their ability to thrive in hybridized form, others can produce unpredictable results. And, if you're new to breeding dogs, do some research and ensure both pups are healthy enough for procreation.

Make A Plan

Before you begin, you must make sure you have a plan in place. Don't be afraid to change things as time passes. Just ensure that any changes are for the better!

Here are some examples of elements to include in your plan:

? What kind of breed(s) do you want to work with?

? Will these dogs be raised indoors or outdoors?

? Are they bred primarily for profit or companionship purposes?

? How much experience do you already have with dogs/puppies? 

The Pedigree Of The Dog

Your dog's pedigree is important in crossbreeding, as it tracks the lineage of a dog's genetic history, so you can tell what they're likely to pass onto their offspring. When looking at pedigrees, it's important to know that dogs bred with other dogs with health conditions should probably not be used as parents for any more offspring. 

Health Conditions To Look Out For

Here are some of the tests your dogs should take before you breed them:

? Hip dysplasia - This common disorder causes pain in dogs' hips with age. If a dog passes this test, they won't develop hip dysplasia while they're still young adults. The downside is there's no way to know whether or not your older dog will develop one. If they do, they'll need surgery to prevent serious damage. But certain meds such as Dasuquin advanced or Carprofen for dogs can be prescribed to reduce pain temporarily. 

? Eye problems - Dogs with eye problems might suffer from blindness and/or glaucoma and other vision-related illnesses. Therefore, tests should be performed to ensure the offspring don't inherit any genetic defects. The percentage of the offspring being clear, a carrier, or affected by the condition can be calculated by testing the parents. If one parent is clear, but the other is a carrier, then approximately 50% of puppies will be clear, whereas the other 50% will be carriers. Nonetheless, if a pup does have some problems, such as eye-related issues, it’s best to consult a doctor and get some dog eye medications. 

Find Out The Size Of The Parents

When trying to create a healthy hybrid dog, it's important to consider the size and build of both parents. If one parent is large and the other is small, there's a chance that the resulting hybrid will be too large or too small. If both parents are small, on the other hand, there's also a chance that their offspring will be too small.

If you want to avoid creating an unhealthy hybrid dog by pairing two breeds with different sizes and builds together, take measurements of heights and weights. Then compare those numbers and ensure they're compatible before deciding whether or not they'll produce healthy puppies together! 

Vaccinations Before Breeding Them

Vaccinations are vital for all dogs, but they're especially important for hybrids. It is because crossbreeding can create a higher risk of health problems in the puppies than in pure breeds.

You must ensure that both parents are up-to-date on their vaccinations because it protects both the mother and puppies from diseases. Vaccines can also protect against diseases requiring a C-section with a mortality of around 3.11%, which would be a lot riskier than having pups naturally. 

Vaccinations After Breeding

As a responsible dog owner, you should administer all necessary vaccinations within the stipulated time after the puppies are born. The American Veterinary Medicine Association (AVMA) recommends that all dogs receive distemper, hepatitis, leptospirosis, parainfluenza virus, and parvovirus vaccines before they're six months old.

The best time to administer these vaccinations is around four weeks after birth. Still, it’s important not to wait too long until administering them since most diseases can be transmitted before this point in time. 

Mother’s Health During Pregnancy

It’s crucial to pay attention to the mother’s health while she is pregnant. A good diet for her to eat while pregnant, whether raw or canned dog food, is a must. She must get all the nutrients so that both mom and puppies can develop strong immune.

Also, if the bitch is on some sort of medication like Insulin for dogs, if she has sugar, or medicine for fleas and ticks on dogs while suffering from a flea or tick infection, or Antibiotic for dogs, the same shall be continued during her pregnancy as well. Still, it’s wiser to consult a veterinarian. 

Prepare For The Birth And Upbringing Of The Puppies

You'll want to prepare for the whelping process as soon as you know your dog is pregnant. You'll need:

? A whelping box is a small room or space where the mother will birth, nurse and care for her puppies. If possible, choose a location that doesn't have hard floors or sharp corners where the puppies could get hurt.

? You can take your dog for a short walk. Also, try to massage her nipples to stimulate contractions. Gently massaging her abdomen will also help relieve some pain while in labor.

? To keep the little pups entertain, have some Kong toys or Nexgard chewables around their area so they can have something fun to play with when they're not nursing.

? It's also helpful if they have soft dog beds on which they can lay down. This is especially important if you plan on having more than one litter at once! 


It’s a great idea to start by researching and talking with experts, such as breeders or veterinarians. The first step is planning a successful cross-breeding. Then, prepare yourself for the many stages of pregnancy and birth. Make sure each stage goes smoothly so both parents and pups can thrive together.

Was this article helpful?

You May Also Like

Image for Gastric Dilatation Volvulus In Dogs
Gastric Dilatation Volvulus In Dogs

Learn more about this disease and how to spot it.

Read More
Image for The Ultimate Guide to Dog Breeds
The Ultimate Guide to Dog Breeds

Listing Out Different Dog Breeds With Informative Descriptions

Read More
Image for Dog Breed Weight Chart
Dog Breed Weight Chart

How Much Dogs Weigh by Breed

Read More