1. Anipryl
Anipryl
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Anipryl
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At a Glance
Highly effective in treating CDS and pituitary conditions
Works by boosting dopamine levels in the brain
Finally there is hope for your dog with CDS
  1. Anipryl

Anipryl

RXPrescription required
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Generic available: Generic to Anipryl is Selegiline
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At a Glance
Highly effective in treating CDS and pituitary conditions
Works by boosting dopamine levels in the brain
Finally there is hope for your dog with CDS

Studies have found that 62 percent of dogs between the ages of 11 and 16 have at least some symptoms of Cognitive Dysfunction Syndrome (CDS). Sometimes called Doggie Alzheimer's, the symptoms of canine CDS are similar to those of human Alzheimer's patients: disorientation, confusion, memory loss, and changes in personality. Thankfully, there is hope.

Anipryl is an oral tablet that is highly effective in treating canine CDS. It works by boosting the dopamine levels in the brain. In fact, 70 percent of dogs with Canine CDS responded positively after a month of treatment. Anipryl is also used to treat conditions caused by an over-secreting pituitary gland. Anipryl works by suppressing the pituitary gland directly. This is a new and innovative approach to treating such conditions. It may take anywhere from one to three months of treatment before any positive results show.

It is easy to administer and does not require monitoring, since it does not inhibit the adrenal gland's function and will not cause adrenal toxicity or insufficiency. It can be given with food and is available in multiple dosage sizes.

Selegiline, the main ingredient in Anipryl can trigger certain side effects like vomiting, extreme bowel movements, increased thirst and urination, agitation, drowsiness, disorientation, lack of appetite, hair loss, etc.

A generic alternative to Anipryl is Selegiline.

What Is Anipryl for Dogs?
Answer

Anipryl is very effective to deal with Cushing’s diseases and canine cognitive dysfunction syndrome. Pituitary tumors lead to Cushing’s diseases in dogs. Anipryl has a monoamine oxidase inhibitor, Selegiline Hydrochloride, as an active ingredient. This is a prescription-only drug and helps in the control of clinical signs of the above issues in dogs.

Can Anipryl Be Split?
Answer

Anipryl is an oral medication in the form of tablets and chewable. Dogs often make a fuss about taking pills directly. If you face the same issue, you can try administering the drug by feeding it with food or treats of his or her choice. If you split and mix the medicine with food, remember to administer the whole dose and not miss any part of the dosage.

What Does Anipryl Do for Dogs?
Answer

Anipryl is very effective to deal with Cushing’s diseases and canine cognitive dysfunction syndrome. Pituitary tumors lead to Cushing’s diseases in dogs. Anipryl has a monoamine oxidase inhibitor, Selegiline Hydrochloride, as an active ingredient. Anipryl works by boosting the dopamine levels of your dog’s brain. Anipryl has an overwhelming response for dogs with cognitive dysfunction after a month of usage. The drug also helps to treat conditions arising from the over-secreting pituitary gland. The results may vary among different dogs. The effects may start showing after the first month or can even show after three months of treatment.

Can Anipryl Cause Restlessness in Dogs?
Answer

Restlessness is one of the most common side effects of Anipryl. So post medication if your dog shows signs of the same do not be worried. But, if there are any increasing concerns, do consult a veterinarian immediately.

Can Anipryl Help With Pancreatitis in Dogs?
Answer

Anipryl is very effective to deal with Cushing’s diseases and canine cognitive dysfunction syndrome in dogs. It does not treat pancreatitis in dogs. Please contact your veterinarian for further clarification and information on the same.

Can Dogs Eat Meat While on Anipryl?
Answer

The dogs can eat meat during the administration of Anipryl. Contact your veterinarian for understanding the foods that your dog can have during this time.

What Are the Side Effects of Anipryl?
Answer

The most common side effects of Anipryl that have been observed are restlessness, vomiting, diminished hearing, diarrhea, loss of appetite, behavioral changes, disorientation, and hyperactivity.

How Effective Are Anipryl Dogs?
Answer

Anipryl is very effective to deal with Cushing’s diseases and canine cognitive dysfunction syndrome. Pituitary tumors lead to Cushing’s diseases in dogs. Anipryl has a monoamine oxidase inhibitor, Selegiline Hydrochloride, as an active ingredient. Anipryl works by boosting the dopamine levels of your dog’s brain. Anipryl has an overwhelming response for dogs with cognitive dysfunction after a month of usage. The drug also helps to treat conditions arising from the over-secreting pituitary gland. The results may vary among different dogs. The effects may start showing after the first month or can even show after three months of treatment.

Is Anipryl Safe for Dogs?
Answer

Anipryl is safe for dogs. But, do not use it on pets that are hypersensitive to selegiline. The use of the medicine is also not recommended for non-pituitary origin diseases. Also, note that the medicine is yet to be tested on lactating, nursing, or pregnant pets. The administration of the medicine along with any other medications like phenothiazines, insulin, sulfonamides, and phenytoin should be done under the strict supervision of a certified veterinarian only. Contact your veterinarian, if you see any complications arising in your dog because of the medications.

How Long Does It Take Anipryl to Work?
Answer

Anipryl works by boosting the dopamine levels of your dog’s brain. Anipryl has an overwhelming response for dogs with cognitive dysfunction after a month of usage. The drug also helps to treat conditions arising from the over-secreting pituitary gland. The results may vary among different dogs. The effects may start showing after the first month or can even show after three months of treatment.

Is There a Generic for Anipryl?
Answer

The generic form of Anipryl is Selegiline hydrochloride.

What Is the Dosage of Anipryl?
Answer

Anipryl is an oral drug. The medicine is administered in the morning and the dosage is one whole tablet. For canine cognitive dysfunction, the dosage is 0.5-1.0mg/kg of body weight. For pituitary tumors, the dosage is 1.0mg/kg of body weight. The results start to show after a month of usage. But in case there are no signs of recovery even after 2 months of usage, the dose needs to change. Contact your veterinarian to get your pet checked and revise the dosage.

Selegiline Hydrochloride

Overview 

Selegiline Hydrochloride acts monoamine oxidase-B inhibitor. The drug is used for the canine cognitive dysfunction treatment among the pats and helps tackle Cushing’s disease. The dopamine levels of the brain increase by the action of this medication. The metabolization of the drug leads to methamphetamine, amphetamine, and L-desmethylselegiline. These together act as stimulants for the central nervous system.


Uses 

This medication is the only FDA-approved treatment available for nine cognitive dysfunctions. The onset of the actions of this medication can vary between 4 to 12 weeks, but most pets show improvement after a month of treatment. This condition can only improve with time. The medication’s neuroprotective effects lead to an increase in dopamine levels. However, it is worth mentioning that the drug does not cure can and cognitive dysfunction but can help in improving the quality of life under such a condition.


Special Precautions

If any accidental overdosing of this drug happens, it is crucial to inform a veterinarian and seek medication immediately.


Mechanism of Action

The old administration of the medication leads to a rapid release of the drug into saliva. An active pharmaceutical ingredient gets through the buccal mucosa. It helps to trigger the metabolism rapidly due to the fast-paced action. There are mild clinical benefits available from MAO inhibitors during the treatment. One of the byproducts of MAO catalyzed a mind oxidation reaction is hydrogen peroxide, and it can further convert reactive oxygen species leading to cytotoxic. It can ultimately impact reducing the oxidative stress of the animal. The antioxidant property is a critical neuroprotection mechanism that this medication helps provide.


Known Drug Interactions

Numerous drug interactions can happen with this medication. In the event of sighting such interactions, it is ideal to stop using the drugs for two weeks before giving selegiline. This period will serve as a good wash-off period and help avoid any aggravating drug interaction scenarios. 

The interactions can happen with the drugs like phenylpropanolamine, monoamine oxidase inhibitors, pseudoephedrine, tricyclic and tetracyclic anti-depressants, selective serotonin, etc.


Brand/Generic Equivalents

Anipryl

Anipryl is a medication for veterinary use in treating certain complications in dogs alone. The medication is found extremely effective in dealing with canine cognitive dysfunction syndrome as well as various Cushing’s diseases due to pituitary tumors in dogs. Selegiline Hydrochloride, a monoamine oxidase inhibitor is an active ingredient in the medicine that helps in controlling the clinical signs associated with the abovementioned complications in dogs. The medication is available only on prescription and is in the form of a tablet meant to be taken orally. 

The most common side effects are mostly mild to moderate vomiting, diarrhea, diminished hearing, disorientation, loss of appetite, and hyperactivity, restlessness, or other behavioral changes.

Do not use the medicine for diseases that are not of pituitary origin and in animals that seem to be hypersensitive to selegiline. As the possible effects of Anipryl on pregnant or nursing animals have not yet been clinically proven, the use of medicine on such animals can be risky. Take extra care when given with insulin, phenytoin, sulfonamides, and phenothiazines, and in no way should the medicine be used with ephedrine. It will be always good to inform the veterinarian on the kinds of medications the pet is already taking so that adequate precautions can be taken. 

For treating Cushing’s disease: An oral dose once a day for a two-month period; the dosage can be doubled for one month following this if the pet shows no response to the smaller amount.

For treating CDS: A smaller oral dose once a day for a one-month period; if there is no improvement, the dose may be doubled for one month. Beyond that, a veterinarian should be consulted to discover if another underlying problem is causing the dog’s symptoms.

Anipryl is manufactured by Pfizer
Option UPC/SKU
5mg, 30 pills 087219032169
10mg, 30 pills 087219032183
15mg, 30 pills 087219032206
30mg, 30 pills 087219032220

How to Order Prescriptions Online

1. Find the Right Product

Make sure it matches your pets prescription. Don’t forget to compare the dosage for pills/capsules!

2. Add to Cart

Just like any other online store. Make sure the quantity matches what’s been prescribed by your vetinarian.

3. Tell Us About Your Pet and Vet

Answer some questions during checkout and we’ll contact your vet and verify the prescription for you. You can also mail us the written prescription.

4. That’s It!

If the prescription has any refills, processing your future orders for that medication can be expedited.

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