1. Proin Extended Release
Proin Extended Release
RXPrescription required
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Proin Extended Release
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At a Glance
Controls urinary incontinence in dogs due to urethral sphincter hypotonus.
Helps tighten the bladder and urethral muscles to help prevent urine leaking and accidents.
Once-a-day dosing and deliver a controlled release mechanism for steady absorption.
  1. Proin Extended Release

Proin Extended Release

RXPrescription required
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At a Glance
Controls urinary incontinence in dogs due to urethral sphincter hypotonus.
Helps tighten the bladder and urethral muscles to help prevent urine leaking and accidents.
Once-a-day dosing and deliver a controlled release mechanism for steady absorption.

Proin Extended-Release for dogs with urinary incontinence

An increasing number of pet owners are facing the heart-wrenching problem of incontinence in their dogs, which causes accidents in the house and can lead to serious health problems if not treated quickly and effectively. Proin Extended-Release is one treatment option that your veterinarian may recommend to help ease your dog's symptoms of incontinence. Here's everything you need to know about Proin Extended-Release, including how it works, what it does, side effects, and more.

What is Proin Extended-Release?

Proin ER is a prescription medication used to treat urethral sphincter hypotonus in dogs. This condition occurs when there is muscle weakness in one of your dog's urethral sphincters, causing urine to leak out unexpectedly. The use of Proin ER allows these muscles to function properly again.

How does Proin Extended-Release work?

Proin extended-release is a prescription medication used to help control urinary incontinence in dogs due to urethral sphincter hypotonus, a weakening of the muscle in the urethra. The medication works by relaxing smooth muscles and stimulating the contraction of excitable tissues. It works by relaxing bladder muscles and stimulating the contraction of pelvic floor muscles that are normally involved in controlling urination.

PROIN ER™ (phenylpropanolamine hydrochloride extended-release tablets) Provides the same proven efficacy as PROIN® (phenylpropanolamine hydrochloride) chewable tablets in extended-release tablets for once-a-day dosing. Our patented extended-release technology provides a controlled release mechanism that achieves steady absorption. For the control of canine urinary incontinence due to urethral sphincter hypotonus. Urethral sphincter hypotonus causes canine urinary incontinence as a result of weakened muscles of the urethral sphincter.

Phenylpropanolamine hydrochloride

Proin ER may mask signs of incontinence due to urinary tract infection. Proin ER is not effective in dogs with incontinence due to neurologic disease or malformations. Proin ER may cause hypertension; therefore, use with caution in dogs with pre-existing heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension. Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result. Use with caution in dogs administered halogenated gaseous anesthetics as this may increase the risk of cardiac arrhythmias. A laboratory study on human blood revealed that phenylpropanolamine (PPA) used in conjunction with aspirin may potentiate decreased platelet aggregation. Proin ER may cause increased thirst; therefore, provide dogs with ample fresh water. The safe use of Proin ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating.

Administer Proin chewable tablets, to the exact specifications of your veterinarian.

Store at controlled room temperature 68-77°F, excursions permitted between 59-104°F.

How to Order Prescriptions Online

1. Find the Right Product

Make sure it matches your pets prescription. Don’t forget to compare the dosage for pills/capsules!

2. Add to Cart

Just like any other online store. Make sure the quantity matches what’s been prescribed by your vetinarian.

3. Tell Us About Your Pet and Vet

Answer some questions during checkout and we’ll contact your vet and verify the prescription for you. You can also mail us the written prescription.

4. That’s It!

If the prescription has any refills, processing your future orders for that medication can be expedited.

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