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At a Glance
Promotes healthy recovery from a myriad of conditions
Treats serious cases of bronchial and diseases in the lungs, intestines, spinal cord, brain and blood.
Provides relief in emergency anaphylactic reactions, spine trauma, and shock


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Generic available: Prednisone / Prednisolone
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At a Glance
Promotes healthy recovery from a myriad of conditions
Treats serious cases of bronchial and diseases in the lungs, intestines, spinal cord, brain and blood.
Provides relief in emergency anaphylactic reactions, spine trauma, and shock

Allergy season is just as much a threat to animals as it is to humans. If your dog or cat is experiencing itching, hair loss, skin irritation, or more serious symptoms such as spinal trauma or bronchial lung disease, Prednisone can help.

Prednisone has been proven to combat the natural effects of allergens by treating the symptoms of low corticosteroid levels in animals whose bodies are producing below normal levels. Prednisone can be used alone or with other medications. It has been known to promote healthy recovery from multiple conditions including eczema, dermatitis, allergic reactions, inflammatory eye conditions, otitis externa, arthritis and bursitis, ulcerative colitis and nephrosis.
  • Skin & Coat Pharmacy
  • Itch Relief Pharmacy
  • Ear Care Pharmacy
  • Arthritis & Pain Pharmacy
  • Allergy Relief Pharmacy
  • Asthma & Respiratory Pharmacy
  • Care Wellness Philosophy
  • Alopecia (Hair Loss) Skin & Coat Health
  • Lick Granuloma Skin & Coat Health
  • Dermatitis Skin & Coat Health
  • Flea Allergy Dermatitis Skin & Coat Health
  • Sarcoptic Mange Skin & Coat Health
  • Thyroid - Hypothyroidism Endocrine Health
  • Arthritis (Osteoarthritis) Arthritis & Joint Health
  • General Allergies Allergies
  • Ivermectin Sensitivity Allergies
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  • Lamb Allergy Allergies
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  • Prescription Pharmacy Type
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What Does Prednisone Do to Dogs?

A dosage of Prednisone for dogs helps them combat allergies. While on Prednisone, dogs can regain normal levels of corticosteroid. Corticosteroids for dogs can lower inflammation quickly. The prednisone dosage helps retain the corticosteroids so that they can stay safe from allergens. Besides, dogs on prednisone have also been found to recover effectively from health conditions like arthritis, eczema, dermatitis, inflammatory eye problems, and so on.

Does Prednisone Help With Pain in Dogs?

Yes, Prednisone can help with pain in dogs. Prednisone somewhat works like a cortisone shot for dogs. Cortisone shots for dogs are anti-inflammatory drugs that can ease pain in your dogs. Prednisone also acts in a similar manner. Giving your dog Prednisone dosage will lower the inflammation. That in turn will decrease the pain and redness, and will quickly heal the swelling. Prednisone is also used to cure diseases in the lungs, intestines, brain, spinal cord, and blood. The drug can also handle bronchial infections. Prednisone is also known to provide relief in the event of spine trauma, and shock.

What Are the Side Effects of Prednisone in Dogs?

There are a few known warnings and side effects of Prednisone for dogs. Firstly, the drug should not be administered to dogs that are allergic to its contents. It should also not be used in dogs that have fungal infections. Secondly, for pregnant dogs, using Prednisone can lead to premature labor, which is unlikely to turn out in your favor. Finally, since it is a type of steroid, you should not cease its administration suddenly. If the dosage is to be stopped, you should do it gradually. Besides, the drug should not be used with other non-steroidal or anti-inflammatory medications. Side effects of Prednisone in dogs include weight gain and an increase in thirst, hunger and urination, vomiting, diarrhea, and fever.

How Much Prednisone Can My Dog Take?

It depends on how long a dog can stay on Prednisone. Usually, a 0.5 mg dosage per pound of body weight is treated as ideal. In that case, a 10-pound dog or puppy can do with 5 mg of Prednisone each day; a 30-pound dog can do with 15 mg Prednisone dosage; and heavier dogs, weighing over 50 pounds will require 25 mg, plus a bit more, each day. In some cases, you might want to suppress the dogโ€™s immune system. For that, you should administer 1 mg Prednisone per pound of body weight.

Can Prednisone Make a Dog Act Different?

Yes, Prednisone can make a dog act differently. This is one of the few side effects of Prednisone on dogs that we are aware of right now. Prednisone is a type of corticosteroid treatment. Dogs undergoing this type of treatment are usually less playful. They feel nervous and restless, less confident and more fearful, and can sometimes bark without any reason. These dogs are also easily startled and might act aggressively when they feel disturbed.

Can Prednisone Make My Dog Sleepy?

Yes, Prednisone can make your dog sleepy, especially in cases of long-term use. The dosage makes the dog weak and lethargic. As a result of that, your dog is likely to feel sleepy if the dosage continues for a long time.

Is Shaking a Side Effect of Prednisone in Dogs?

Shaking is not a direct side effect of Prednisone in dogs. However, it can make the dog feel jittery and alert. Your dog will also be more nervous and restless than usual. You can also expect it to show a bit of aggression every now and then, accompanied by some barking.


Prednisone belongs to the category of gluco corticoids of medicines and is used in treating autoimmune diseases in dogs and cats. Autoimmune diseases are those which cannot be prevented or treated and occurs when the immune and inflammation systems, which are intended to protect the body against diseases, turn against the body causing severe damage or even death. Curiously enough, in many cases, this happens without any specific reason. Prednisolone is anti-inflammatory in nature and could be used to treat allergies, endotoxic shock caused by bacterial infections apart from auto immune conditions like bronchial and lung diseases, and brain and blood diseases. In addition, it is used as a supplement in oncology treatment, Addison's disease and adrenal gland disorder.

Prednisolone should never be used in animals that are allergic to this drug, and in those with fungal infections. Pregnant animals should not be treated with Prednisolone as it might induce premature labor. Never terminate Prednisolone therapy suddenly; and the animal should be taken off the drug in phases, to avoid difficulties.Prednisolone might adversely react with other medications such as non-steroidal anti-inflammatories. It affects the whole body system of the animal, and hence should be administered only in crucial emergencies and life threatening situations.

Short term use rarely causes side effects. However, more frequent use can interfere with many of the body systems. Possible side effects include: weight gain, excessive panting, increased thirst, hunger and urination; vomiting and diarrhea. Cushingโ€™s syndrome may manifest itself following prolonged or repeated steroid therapy. Prednisone may also mask the symptoms of developing disease, such as fever, since it suppresses the immune response.

Some of the side effects include increased thirst and appetite, breathlessness, nausea, restlessness, stomach ulcers and loose motion. Prolonged use of this drug might lead to loss of hair coat, slackening of muscles, liver damage and behavioral changes.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Prednisolone is available in 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg and 50 mg tablets apart from 3 mg/ml syrup, 1 mg/ml suspension and injectable forms. Doses might vary depending on the ailment. The recommended anti-inflammatory doses range from 0.2 to 0.6 mg/kg, administered twice a day, immunosuppressive doses range from 2 to 6 mg/kg, thrice daily.

When administering medication to a pet, always follow the directions of your veterinarian.

Store at room temperature, away from moisture and heat.

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