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August 07, 2013
Celecoxib, the generic of Celebrex, is a Non-Steroidal Anti-Inflammatory Drug (NSAID) used to treat chronic joint pain, such as arthritis or pain caused by local swelling. Like all NSAIDs, celecoxib blocks the production of prostaglandins, which are hormones that are released in affected areas (i.e., joints) and cause swelling and increased sensitivity.
Since not all prostaglandins do the same thing, celecoxib is tailor made to target just the prostaglandins that cause local swelling (cox-2) and not the ones that help protect our GI tract (cox-1). Essentially, celecoxib is a pain relief drug that is safe to use for extended periods without having to worry about undue damage to the stomach lining.
Since celecoxib is a drug intended for use in humans, its use in dogs or cats is considered an extra-label drug, and should not be given without a prescription from a vet.
Should not be given to dogs with a preexisting heart condition or are at risk for a stroke. Celecoxib should not be used in dogs that are pregnant. For dogs that have issues with bleeding or ulcers, celecoxib should not be given. Dogs still suffering from chronic pain after taking celecoxib should consult their vet before increasing their dosage. Consult with your vet regarding any allergies or sensitivities.
Since celecoxib is a drug designed for use in humans, and its use in dogs and cats is considered extra-label, no estimated dosages for pets have been published. Consult with your veterinarian and find out what is best for your pet.
Unlike other NSAIDs that block the production of prostaglandins, cox-2 NSAIDS like celecoxib are known to knock the ratio of cox-1 and cox-2 prostaglandins off kilter, which can lead to clotting and blocking of arteries. This can increase the user's risk for heart attack or stroke.
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