Incurin Tablets - 1 mg

Incurin is a prescription medication recommended by veterinarians to relieve urinary incontinence in female dogs. This happens in spayed female dogs due to hormonal changes. Since the medication comes in tablet form and requires oral administration, it can be given in a pill pocket, as treat, or in your dog's favorite wet food. Usually, Incurin is administered in 1mg dosage per day for at least a week or two. If the dog shows or doesn't show any effect to the normal or lower dosage, it's then modified with increased dosage to show the impact. However, don't make any dosage-related decisions without consulting your trusted veterinarian first.

Incurin tablets are counted among the most effective treatments for the control of estrogen-responsive urinary incontinence in spayed dogs. This mediation is beneficial for female dogs who have had surgery to remove ovaries and uterus through a process called Ovariohysterectomy. The medication has been widely used for this purpose globally for over 12 years. Since Incurin is a medication that causes bodily change, it requires a prescription from a reliable and licensed veterinarian. The drug has a natural estrogen called Estriol as the active ingredient. This increases the urethra's resting muscle tone and supplements estrogen in the body.

Like most other dog meds, Incurin is not dependent on the body weight of the dog. Regardless of the size, age, and weight, all dogs must receive an initial dose of two tablets of 1 mg Incurin tablets, orally administered once per day. The dosing schedule is a minimum of 14 days for the initial dose. Once the urinary incontinence has been controlled, the effective daily dose of Incurin should be brought to lower doses. This should be done by decreasing it stepwise from 2 mg once daily to 1 mg daily and then 0.5mg daily. This will depend on the response of the individual dog to the treatment. Maintain at least a week of the gap between each dose adjustment. Once the lowest daily dose has been identified, the dose must be further reduced by administering once every two days.

Both Incurin and Proin are US Food and Drug Administration (FDA-approved) tablets for controlling urinary incontinence in dogs. These medications are intended to aid with urethral sphincter hypotonus, which occurs due to age or spaying. The active ingredient in Proin is phenylpropanolamine hydrochloride, whereas it's Estriol in Incurin. A scientific test conducted on 119 client-owned dogs on Incurin and Proin revealed that both medications are on par with each other in terms of efficacy. However, Proin gets a slight edge because it needs to be administered only once a day instead of 2-3 times a day with Incurin.

Incurin is a relatively safe medication for dogs and shouldn't cause aggressiveness in them. However, a study on 224 dogs by drugs.com revealed that on prolonged dosage duration between 14 to 42 days, around 1.8 percent of dogs showed aggressiveness. A total of three dogs had to be euthanized because of uncontrolled aggressiveness. While the number is pretty small, there are still chances that the medication might cause aggressiveness in some dogs. It's imperative to consult your veterinarian if you see any signs of aggressiveness in your dog when on Incurin.

Incurin and Propalin are both used to treat incontinent dogs. While the former is an estrogen, Propalin is alpha-adrenergic phenylpropanolamine. While spayed dogs might respond well to estrogen therapy, they sometimes cease to respond to the treatment because of the desensitization of estrogen receptors. Despite increasing the dosage, some dogs don't show any response. A similar phenomenon happens with Propalin as well. In such cases, veterinarians sometimes recommend a combination of both to increase the efficiency of the medication. Therefore, it's safe to deduct that both these medicines can be used together. However, dog parents will need to keep an eye on the dosage and frequency of dosing for both medications.

Incurin and DES are both used to treat canine urinary incontinence in spayed females effectively. However, Incurin is a newer medication with a nuclear retention time of 1 to 4 hours. DES, on the other hand, has a nuclear retention time of 6 to 24 hours. The shorter nuclear retention time of Incurin lowers the risk of undesirable side effects.

Incurin should not be given to male canines. Incurin includes estriol, a type of estrogen, and it can cause feminization as well as other major health issues in male dogs. Incurin is only licensed for the treatment of hormone-responsive urine incontinence in spayed female dogs. If you are concerned about your male dog's urinary health, consult your veterinarian about alternate treatment choices.

No, Incurin shouldn't be administered to dogs who are nursing or pregnant. Estriol, a kind of estrogen found in Incurine, has been shown to be damaging to fetal development and milk supply. It's vital to discuss alternative urine incontinence treatments with your veterinarian if you think your dog might be pregnant or nursing puppies. Your veterinarian can provide a safe and efficient treatment regimen for your dog and her puppies.

Give Incurin as soon as you remember if you miss a dose. If the time for the subsequent dose is approaching, omit the missed dose and go back to your regular dosing plan. To make up for a missed dose, avoid giving a double dose as this may raise the chance of unwanted effects. To make sure the drug is successful in treating your dog's urine incontinence, it's crucial to stick to a regular dosing plan. Consult your veterinarian if you have any questions about missing doses or the Incurin dosage schedule.

The risk of cancer linked to Incurin is thought to be extremely low and there is no proof of Incurin canine cancer. Although Estriol, a type of estrogen is found in Incurin, the likelihood of developing cancer while using this prescription is extremely low. According to certain research, long-term estrogen treatment use in dogs may raise their risk of developing certain cancers such as uterine and mammary tumors, however, these studies have not specifically looked at its use. You should see your veterinarian if you have any questions about the safety of Incurin.

No, it is not advised for canine spinal cord injury. Before giving Incurin to dogs with spinal cord injuries, it's crucial to speak with a veterinarian. Dogs with urine incontinence brought on by spinal cord injury may not respond well to Incurin, which is often used to treat this condition in dogs. The veterinarian can identify the underlying cause of the incontinence and suggest a suitable treatment strategy that can involve medication, surgery, or other measures. Dogs with spinal cord injuries may occasionally require a mix of therapies to address incontinence.

In dogs, Incurin has an elimination half-life of around 8 hours, meaning that it takes roughly 8 hours for half of the drug to leave the body. Approximately 97% of the medicine should have left the body after 5 half-lives or 40 hours. However, the precise time it takes for Incurin to be eliminated from a dog's body can differ based on things like the dog's age, weight, and general state of health. Even if your dog's symptoms go better before the medication is done, it's still crucial to provide Incurin exactly as the doctor instructs and finish the entire course of treatment.

Depending on the individual dog and how they respond to the drug, a dog may need to take Incurin for a different amount of time. Many dogs may need to take Incurin for the remainder of their life because it is often used as a long-term treatment for urine incontinence. The dog's response to the drug and any alterations in its health status may necessitate modifying the Incurin dosage over time. When administering Incurin, it's crucial to follow the veterinarian's instructions, and regular checkups can help you keep track of how well your dog is responding to the drug.