Frontline Plus for Dogs
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At a Glance
Provides fast-acting, long-lasting flea and tick protection for dogs 8 weeks or older weighing between 5 and 132 pounds
Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae
Waterproof 24 hours after application
Easy to apply for once a month for lasting protection
Proven protection trusted by veterinarians for more than 20 years, with separate formulations available for dogs and cats

Frontline Plus for Dogs

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At a Glance
Provides fast-acting, long-lasting flea and tick protection for dogs 8 weeks or older weighing between 5 and 132 pounds
Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae
Waterproof 24 hours after application
Easy to apply for once a month for lasting protection
Proven protection trusted by veterinarians for more than 20 years, with separate formulations available for dogs and cats

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Boehringer-Ingelheim Logo

Ultimate Guide to Frontline Plus For Dogs

Meet the Trusted Parasite Treatment: Frontline Plus For Dogs!

Frontline Plus for Dogs is a trusted flea and tick treatment that provides complete protection for your furry friend. This powerful flea tick topical solution is specially formulated to kill fleas, flea eggs, flea larvae, and ticks. It is ideal for pet owners seeking an effective way to control fleas and ticks on their dogs and prevent further infestations.

Key Benefits

  • Kills Existing Adult Fleas: Frontline Plus effectively kills existing adult fleas within 24 hours, breaking the flea life cycle and preventing new flea infestations.

  • Comprehensive Tick Control: This tick treatment covers all stages of the tick life cycle, ensuring complete tick prevention and reducing the risk of diseases such as Lyme disease.

  • Flea and Tick Protection: Provides long-lasting waterproof flea protection, keeping your dog protected even after baths or swimming.

  • Trusted by Pet Owners: Frontline brand products have been trusted by pet owners for years for their reliability and effectiveness in flea and tick control.

Application and Usage

  • Easy Application: Using the snap applicator tip, apply Frontline Plus directly to your dog's skin between the shoulder blades. The sebaceous glands in your dog's skin will continuously replenish the flea control treatment across the entire body, including the hair coat.

  • Monthly Dose: Just one monthly dose provides protection against fleas and ticks, making it easy to keep your dog protected year-round. Reapply Frontline monthly to ensure continuous protection and control of fleas and ticks.

  • Waterproof Formula: Frontline Plus is a waterproof flea treatment, ensuring your dog remains protected even after getting wet.

Suitable For

  • Dogs and Puppies: Suitable for dogs and puppies 8 weeks of age and older, weighing at least 5 pounds.

  • Various Sizes: Available in a purple box for small dogs, ensuring the correct dosage for dogs weighing different amounts.

Additional Features

  • Kills Chewing Lice: In addition to fleas and ticks, Frontline Plus also kills chewing lice, providing comprehensive parasite control for your dog.

  • Prevents Further Infestations: By killing fleas, flea eggs, and flea larvae, Frontline Plus prevents further infestations in your household, ensuring a clean and safe environment for your pet.

  • Veterinarian Recommended: If your dog experiences any temporary irritation or adverse reactions, contact your veterinarian immediately for guidance.

Instructions for Use

  1. Remove Applicator: Follow the dotted line on the applicator and snap the tip off.

  2. Apply Frontline: Part your dog's hair between the shoulder blades and apply the entire contents of the applicator directly onto the skin.

  3. Avoid Contact: Ensure the treated area is out of reach of pets until dry to prevent them from licking the application site.

Why Choose Frontline Plus?

Frontline Plus for Dogs is an effective solution for pet owners who want to protect their dogs from fleas and ticks. With its long-lasting, waterproof formula, and easy application process, it is designed to keep your dog safe and healthy with minimal effort. Trust Frontline flea and tick treatment to provide the best protection for your beloved pets.

Frontline Plus For Dogs is a veterinarian-recommended dog flea and tick treatment trusted by its customers for 20 years! Frontline Plus is a monthly, spot-on treatment that protects your pet for the next 30 days. From a first-time pet parent to a Frontline dog expert, Frontline Plus guarantees an easy-to-use and effective treatment for your dogs!

How does Frontline Plus For Dogs work?

Frontline Plus For Dogs is a medication with two powerful active ingredients (secret weapons) - Fipronil and (S)-methoprene - that kill adult ticks and fleas at every step of the flea 's life cycle. Frontline Plus kills the parasites on contact by storing itself in the oil glands in your pet 's skin and hair follicles continuously for the next 30 days.

Active ingredient Fipronil is a phenylpyrazole insecticide that disrupts the insect 's central nervous system by blocking the GABA-gated chloride channel that regulates cellular excitability and glutamate-gated chloride (GluCl) channels that controls movement, feeding, and behavior. This causes hyper excitement to the contaminated insect 's nerves and muscles.

Active ingredient (S)-methoprene is an insecticide chemical that controls hatching flea eggs and obstructs the development of the immature flea (i.e., flea pupae and larvae) into a breeding adult.

How is Frontline Plus administered?

Frontline Plus For Dogs is a monthly, spot-on treatment that is applied between a dog 's shoulders and protects your dog for the next 30 days. Frontline Plus products start killing fleas after four hours and effectively kill 100% fleas after 12 hours.

Frontline For Dogs comes in four different color boxes depending on the dog 's weight with differing milliliter (mL) application amounts. Each box has the same percentage of the active ingredients and comes in 3- and 6-month supplies. See the dosage chart below:

Body Weight

Application amount (mL)

5 - 22 lbs.

0.67

23 - 44 lbs.

1.34

45 - 88 lbs.

2.68

89 - 132 lbs.

4.02

What are the precautions of which you should be aware?

Consult your veterinarian before using Frontline Plus because of any potentially negative interactions with other medications that your dog may be taking, like another flea and tick control product.

Also, ensure that your dog is dry before application and that they are not wet for 24 hours after application.

What are the potential side effects of which you should be aware?

Slight irritation at the point of application may be experienced. If the irritation persists, contact your vet immediately.

Frequently Asked Questions
  1. Why am I seeing more fleas on my dog or in my home after applying Frontline Plus For Dogs?

    On the dog, the fleas that come into contact with Frontline Plus rise to the top of the haircoat as they die. In terms of the home, those fleas must have been eggs before you started using the medication. Consecutive monthly applications year-round of Frontline Plus For Dogs will assist with the elimination of an indoor infestation.

  2. Is there Frontline Plus for small dogs?

    Frontline Plus 5 - 22 lbs. is the orange box and for the smallest dogs that can use the medication.

  3. Is Frontline Plus for puppies?

    Frontline Plus for Dogs is safe for use on dogs 8 weeks and older.

  4. Is there other Frontline pet medicine for cats?

    Yes. Frontline Plus For Cats uses the same ingredients, has the same administration, and gives the same results. Frontline Plus can be used on dogs and cats ONLY.

  5. What are the reviews for Frontline Plus?

    Frontline Plus For Dogs reviews rate at 4.5 out of 5 stars. Most reviewers say that Frontline Plus is a quality and effective product for their dogs in any environment, and it is the only widely-trusted flea and tick medicine for their furry best friends.

  6. Explain the Frontline Plus application.

    Frontline Plus must be applied to a pet that is dry and then dry after 24-hours after application. It is a topical solution, spot-on treatment that is applied between the pet 's shoulders via a sterile applicator (i.e., pipette) every 30 days.

Concluding Thoughts

The most important thing that you should know about Frontline Plus For Dogs is its power to protect your dog and home from external parasites (i.e., fleas during their life cycle, ticks, lice, and chewing lice). Dogs should be pampered and protected with the best flea and tick treatment out there in order to have the best quality of life.

DISCLAIMER: This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if this is a suitable product for your pet and for your home.

  • Boehringer-Ingelheim Brand
  • Flea & Tick Pharmacy
  • Boehringer-Ingelheim Manufacturer
  • Spot On/Topical Application
  • Dog Pet Type

How Effective Is Frontline Plus for Dogs?
Answer

Frontline Plus for Dogs is very effective and one of the best flea and tick control measures for dogs. When you use Frontline Plus, dogs are able to get rid of pesky parasites residing on their bodies. Frontline for ticks and fleas guarantees 100 percent flea and tick removal from your dogโ€™s skin. The medication does not only destroy adult fleas and ticks, but it also takes care of all the other stages of these parasites. Besides, Frontline for ticks and fleas starts to take effect within just 24 hours of application. And its presence in your dogโ€™s skin and hair follicles over the next 30 days continuously kills fleas and ticks in the various stages of their life cycles.

Why Is Frontline Plus Not Working on My Dog?
Answer

Before you can know why it is not working for your dog, you first need to know the answer to another question โ€“ how does Frontline work? Frontline plus has two powerful active ingredients known as Fipronil and (S)-methoprene. These two help kill the fleas and ticks, no matter what part of the life cycle they are in. They do so by positioning themselves in the hair follicles of your dogs for 30 days. The medication might not be working probably because it is being washed off and cannot store itself in the said positions. This could happen due to numerous reasons, but most probably because you are bathing your dog too early into the treatment. It is also possible that you are using a dog shampoo that is wearing out the presence of the medication. Ideally, you should wait 24 hours before bathing your dog after you have applied Frontline Plus.

How Long Does It Take Frontline Plus to Start Working?
Answer

Frontline Plus dog tick and flea control will take only 24 hours to start working. During that time, the medication will have spread all over its skin and body. Frontline Plus requires 24 hours to kill all the fleas on your dogโ€™s skin. It takes another 24 hours (total 48 hours) to destroy the tick infestation on their skin. After application, your dog will be safe from fleas and ticks for the next 30 days or so. During that time, the medication will continue to reside in the skin and hair follicles of your dog. In those positions, the Frontline Plus will continue to work its magic and fend off any flea or tick that might try to infest your dogโ€™s skin or take up territory.

How Long After Frontline Plus Can I Bathe My Dog?
Answer

You can bathe your dog 24 hours after you have applied the Frontline Plus for Dogs.

Can You Buy Frontline Plus Over the Counter?
Answer

Yes, you can buy Frontline Plus over the counter. Frontline for dog fleas is a flea and tick treatment medication that does not require any prescription for purchase. Unlike many other pet medications, this one does not need a vetโ€™s prior approval for usage. However, it is expected that you read the instructions on the bottle before you apply it, or talk to a vet if you are confused.

How Often Do You Apply Frontline Plus for Dogs?
Answer

You should apply Frontline Plus for Dogs every 30 days. Under critical circumstances, and the supervision of a vet, you can also apply every 2 weeks. Frontline for puppies should be applied in a much lesser amount (under 1 mL) per body weight than adult dogs.

What to Do if Dog Still Has Fleas After Frontline?
Answer

You can bathe your dog and reapply if your dog still has fleas after Frontline treatment. You should wait for at least 24 hours to see if the first application is working or not.

Do Fleas Jump off After Treatment?
Answer

Fleas are usually dead within 24 hours after you have used the Frontline Plus treatment.

What Differentiates Frontline for Dogs From Frontline Plus for Dogs?
Answer

Frontline is a topical flea and ticks medication that includes the active component fipronil. It is applied to the skin between the shoulder blades of the pet once a month to kill fleas, ticks, and chewing lice. Frontline is effective against adult fleas and ticks but does not kill flea eggs or larvae. Frontline Plus flea and tick for dogs, on the other hand, is also a topical flea and tick treatment with two active ingredients: fipronil and (S)-methoprene. Frontline Plus has an insect growth regulator (IGR) that stops the development of flea eggs and larvae, interrupting the flea life cycle in addition to killing adult fleas and ticks.

How Do I Know if Frontline Plus Worked?
Answer

After applying Frontline Plus to your pet, you can tell if it is working by monitoring your pet for any signs of flea or tick infestation. Check for adult fleas on your pet's skin or fur using a flea comb, or look for flea dirt (small black specks) in your pet's coat. If you see any live fleas or flea dirt, this may indicate that the Frontline Plus is not working effectively. However, remember that it may take a few days for Frontline Plus to start working and for all fleas and ticks to be eliminated. Visit your vet for more advice if you have any concerns.

Where Do You Put Frontline Plus on a Dog?
Answer

It is administered topically to the dog's skin, focusing on the area between the shoulder blades. This area is chosen because it is difficult for dogs to reach with their mouths, which reduces the likelihood of the dog licking the medication off before it has had a chance to be absorbed. Additionally, the skin in this area is thin and well-vascularized, allowing for rapid medication absorption into the bloodstream. It can then circulate throughout the dog's body to protect against fleas and ticks.

Can Too Much Frontline Plus Hurt My Dog?
Answer

Yes, it can. Frontline dog flea treatment is a popular flea and ticks preventative medication for dogs, and while it is generally considered safe, there is a risk of side effects if too much is administered. Overdosing on Frontline can cause symptoms such as vomiting, diarrhea, excessive drooling, tremors, and seizures. These symptoms can be mild or severe and can require veterinary attention.

What Are the Benefits of Frontline Plus Treatment for Dogs?
Answer

Frontline plus flea and tick treatment for dogs offers a variety of benefits. It is highly effective in killing fleas and ticks at all life cycle stages, providing long-lasting protection for up to 30 days with a single application. Also, Frontline Plus is easy to apply, with a pre-measured applicator that can be used to apply the medication directly to the dog's skin.

Is Frontline Plus Recommended by Vets?
Answer

Yes, Frontline flea treatment in dogs is recommended by many veterinarians as an effective flea and tick-preventative medication for canines. It has been on the market for many years and has a proven track record of effectiveness in controlling flea and tick infestations.

What if Frontline Plus Doesnโ€™t Work on My Dog?
Answer

If you have given Frontline Plus to your dog and it doesn't seem to be working, you can do a few things. First, ensure you are using the medication correctly and wait a bit longer to see results, as it can take up to 48 hours to kill fleas and ticks. If this doesn't work, you may want to try a different medication recommended by your veterinarian. Further, it may be necessary to address any underlying health issues or environmental factors that could make it more difficult to control fleas and ticks on your dog.

Frontline plus contains two active ingredients - Fipronil and S-methoprene.

Dogs may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

Dogs/Puppies over 8 weeks of age, weighing 5 - 132 pounds

To apply, simply follow these instructions and repeat every 30 days: Remove one FRONTLINE Plus applicator by lifting and removing the plastic tab to expose foil backing. Then peel away the foil or use scissors to open. Open the applicator by holding upright with foil side toward you and snap applicator tip. Next, part your dog's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the animal's skin. Do not apply on top of the haircoat. Avoid contact with treated area until dry.

Store unused product in original container only, out of reach of children and animals.

https://frontline.com

Frontline is manufactured by Boehringer-Ingelheim
Option UPC/SKU
Orange - 5-22 lbs., 3 Month Supply 350604287001
Blue - 23-44 lbs., 3 Month Supply 350604287100
Purple - 45-88 lbs., 3 Month Supply 350604287209
Red - 89-132 lbs., 3 Month Supply 350604287308
Orange - 5-22 lbs., 6 Month Supply 350604288008
Blue - 23-44 lbs., 6 Month Supply 350604288107
Purple - 45-88 lbs., 6 Month Supply 350604288206
Red - 89-132 lbs., 6 Month Supply 350604288305

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Customer Reviews

Rating Summary 945 review(s)
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731
4 stars
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45
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1 star
46
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Frontline Orders
VERIFIED PURCHASER

Frontline has helped keep my dogs healthy from ticks and fleas.

Norma recommends this item.
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B
Excellent prices
VERIFIED PURCHASER

Cost of flea meds is a fraction of that at pet stores and vet.

Bette Lamore recommends this item.
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H
Great price for Frontline
VERIFIED PURCHASER

Have used PetCareRx for years. The pricing is always more than competitive and delivery is fast.

Helen Vacca recommends this item.
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E
Frontline
VERIFIED PURCHASER

Works great no fleas or ticks

Elaine Harne recommends this item.
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M
Good โ€œStuffโ€
VERIFIED PURCHASER

Excellent flea and tick repellent. Easy to apply. Well tolerated by my dogs.

Michael Elliott recommends this item.
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M
Controls fleas.
VERIFIED PURCHASER

Fleas are not evident.

Mark H recommends this item.
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V
Works Good
VERIFIED PURCHASER

Not cheap but works well!

Vikki recommends this item.
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B
Undecided
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Been using this for years but I don't think it works well anymore.

Barbara recommends this item.
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S
Never Disappoints
VERIFIED PURCHASER

Iโ€™ve used Frontline on my two dogs and cat for at least a decade. Iโ€™ve never been disappointed with the results and itโ€™s fast-acting!

Staci JW recommends this item.
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L
Works Great!
VERIFIED PURCHASER

We have been using Frontline plus for years, and have not seen one flea or tick on either of our dogs, and we have a lot of wild rabbits in our yard.

LCS recommends this item.
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J
30 ticks on our Dog - All Dead!
VERIFIED PURCHASER

We have a Sheltie with long hair here in NJ and there are ton's of ticks here where we walk our dog along a river steam trail! When we take our dog to the groomer, they tell us that they find approx 30 ticks in his fur - all dead. They tells us that what ever we are using - keep using it!

JoeP from NJ recommends this item.
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S
Frontline Plus for Dogs
VERIFIED PURCHASER

I have used Frontline Plus for over 8 years and in all this time my dog has not had any issues with ticks or flees. I have been given suggestions by my vet of new products that have come out and to try them but I've just told him "why fix something if it isn't broken!"

Susan recommends this item.
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K
Works every time
VERIFIED PURCHASER

Tick is very high in this area. Works well

Kandace recommends this item.
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R
thumbs up
VERIFIED PURCHASER

A great price for the meds for my boys :)

rita recommends this item.
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J
We live in tick Country and this product works!
VERIFIED PURCHASER

We live in tick country. We walk our dog along a path near a river and it is just chock full of ticks. Our dog is a Sheltie and the ticks have a lot of hiding places in his thick coat, however every time we take our dog for grooming, the groomer always tells us that whatever we are using, keep using it since they found about 30 dead ticks! We use Frontline Plus for our dog and it does the job!

Jersey Joe recommends this item.
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S
Keeps Flees and Ticks away
VERIFIED PURCHASER

Haven't noticed any issues with my German Shepard or my Dachshund

Scott recommends this item.
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T
Frontline Plus
VERIFIED PURCHASER

My order of Frontline Plus arrived on time and is easy and convenient to use.

Teresa recommends this item.
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J
Has been working..
VERIFIED PURCHASER

Been using frontline since both dogs were puppies. I have been researching newer products that say have a longer life. Will stay with front line until I see results.

J recommends this item.
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G
Quality Product
VERIFIED PURCHASER

Quality Product as expected.

gldnbear recommends this item.
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C
great for my dog
VERIFIED PURCHASER

using frontline for some years now and it has beenvery effective for my dog

carlos recommends this item.
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R
Front Line
VERIFIED PURCHASER

The pricing was ok the savings was a few dollars but the delivery made it worth it.

Rajin recommends this item.
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T
Great product
VERIFIED PURCHASER

Easy to apply, and very effective

Tony Lambert-Watkins recommends this item.
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D
Frontline is the best!
VERIFIED PURCHASER

Frontline is the best flea and tick prevention product, I have used it for 8 years with my Cane and he's never had a flea or tick in his life!

Devin recommends this item.
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P
Very happy with product

Have been using it for years. Very satisfied. Thank you. Heartguard Plus

pokey recommends this item.
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D
No Fleas

I have used Frontline/Frontline Plus for 20 years on my shelties and have never had a flea problem. We are a foster home for 2 Collie/Sheltie rescue organizations and have had/housed 12 dogs. Frontline has been our mainstay flea/tick protection, and I will continue4 to use it until I see a flea.

DaveS recommends this item.
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M
excellent

Lots of ticks in my neighborhood and my dog goes to daycare also and this product has worked great for my dog.

Magsmom21 recommends this item.
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B
I have used the Frontline brand of flea and tick solution for years

I have used Frontline on both my dogs and cats. I've been using Frontline flea and tick treatment on my pets for at least ten years now. I have gained trust in their product line. I have no intentions of switching flea and tick control in the future. Both my dogs and cats have no problems associated with this flea medicine. I highly recommend Frontline Plus for dogs and cats to all of my family and friends.

Brindle225 recommends this item.
Was this review helpful? 5 0

S
Easy to apply

Never had a problem with Frontline. Never saw fleas on my dog with the use of Frontline.

shalomis recommends this item.
Was this review helpful? 3 0

B
frontline

works for fleas, ticks, and other parasites - is easy to apply

birder recommends this item.
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L
Quick shipping

Great price for this product. It's much more expensive in stores and at the vets office.

lake1102 recommends this item.
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