Deramaxx
Deramaxx
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At a Glance
FDA-approved prescription medication for dogs.
Nonsteroidal anti-inflammatory drug (NSAID) effective arthritis relief treatment.
Controls pain and inflammation caused by osteoarthritis and post-surgery.
One 24-hour beef-flavored chew oral tablet.

Deramaxx

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At a Glance
FDA-approved prescription medication for dogs.
Nonsteroidal anti-inflammatory drug (NSAID) effective arthritis relief treatment.
Controls pain and inflammation caused by osteoarthritis and post-surgery.
One 24-hour beef-flavored chew oral tablet.

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Ultimate Guide to Deramaxx

Meet the NSAID Arthritis Treatment: Deramaxx!

Deramaxx is an FDA-approved veterinary-prescribed nonsteroidal anti-inflammatory drug (NSAID) that relieves pain and inflammation caused by arthritis, osteoarthritis (OA), and post-surgery. Deramaxx for dogs is a daily, beef-flavored chew oral tablet that also aids in kidney function, blood clotting, and stomach health.

How does Deramaxx for dogs work?

Deramaxx is a medication with one active ingredient - Deracoxib (brand Deramaxx generic name), which is a nonsteroidal anti-inflammatory drug (NSAID) that is used post-operative (e.g., orthopedic surgery and dental procedures) to reduce pain as well as for the relief treatment of osteoarthritis and other painful conditions.

However, Deracoxib is a different kind of NSAID. To explain, most NSAIDs belong to a class of medications that inhibit the COX-1 enzyme that is necessary for many normal body functions. Deracoxib belongs to the coxib-class of medications that block the COX-2 enzyme that triggers inflammation and contributes to pain in arthritic joints.

How is Deramaxx for dogs administered?

Deramaxx is a single daily dose administered orally and provides your dog with 24-hour protection from pain and inflammation. It is a scored, non-steroidal oral tablet and is a tasty beef-flavored chew that can be given with or without food (with plenty of water available nearby). Treated dogs take the oral chew tablet for a consecutive seven days.

Dogs receive .45 mg to .91 mg/lb./day for osteoarthritis (OA) pain and inflammation. For example, due to the severity, a 30-pound dog will receive a 13.5 mg to 27.3 mg tablet. Dogs with postoperative orthopedic pain have a usual single daily dose of 1.4 mg to 1.8 mg/lb. Another example, Deramaxx dosage for 70-pound dogs would be 98 to 126 mg.

Consult your veterinarian for an as-needed dosage. Deramaxx tablets available are 12mg, 25 mg, 75 mg, and 100mg depending on the strength needed.

What are the precautions of which you should be aware?

Deramaxx (Deracoxib) should not be used in dogs:

  • with hypersensitivity to sulfonamides
  • that are allergic to it or drugs like it (i.e., aspirin or other NSAIDs)
  • that have bloody stools or vomit
  • that have a loss of appetite
  • that have heart complications, liver dysfunction, or kidney disease
  • that are dehydrated or are predisposed to dehydration
  • that are breeding, pregnant, or nursing

Deramaxx (Deracoxib) should be used with caution in dogs:

  • that have or have had stomach ulcers
  • that are taking diuretics (e.g., furosemide)
  • that are geriatric
  • that have a bleeding disorder
  • that have heart disease
  • that use other NSAIDs or corticosteroids

Consult with your veterinarian or pharmacist before asking for or receiving a prescription. Tell your vet if your dog has high blood pressure, blood disorders, and anything listed above.

Tell your vet is taking any of the following medications: aspirin, steroid, any other NSAID, an ACE inhibitor, or an over the counter allergy or cold medicine. It's best to avoid any negative interactions with other drugs that can cause additional side effects or reactions. Your vet may need a physical examination and their medical history.

What are the potential Deramaxx side effects of which you should be aware?

Side effects of Deracoxib in dogs, like other NSAIDs, might occur affecting the gastrointestinal tract, such as vomiting, diarrhea, blood in stool or urine, decreased appetite, and weight gain or loss.

Other adverse reactions experienced might be abdominal pain, bloody vomit, skin afflictions (e.g., pruritus or unordinary bruising), yellowing of eyes, color changes, decreased activity, lethargy, incoordination, and behavioral changes (e.g., aggression, changes in drinking or urination habits, etc.). Digestive, kidney, or liver effects can also occur.

Consult a veterinarian immediately if any of the above effects occur.
Frequently Asked Questions
What Is Deramaxx?

Deramaxx is an FDA-approved Nonsteroidal Anti-Inflammatory Drug (NSAID). It helps relieve inflammation and pain from post-surgery, arthritis, and osteoarthritis in dogs

Deramaxx also helps in blood clotting, kidney function, and stomach health. The Deramxx tablet comes as a chewing, beef-flavored tablet.

Deracoxib or Deramaxx is a coxib class drug and is non-narcotic. The Deramaxx tablets are biconvex, round, chewable tablets.

What Is Deramaxx Used for in Dogs?

Deramaxx is a post-operative medication with one active ingredient - Deracoxib (generic name). Administration of the medicine is common for post orthopedic surgery in dogs and dental surgery to reduce pain.

Deramaxx also helps in the treatment of pain and inflammation associated with osteoarthritis and similar painful conditions.

Deracoxib is a different kind of NSAID. Most NSAIDs belong to a class of medications that inhibit the COX-1 enzyme, which is necessary for many normal body functions. Deracoxib belongs to the coxib class of medications that block the COX-2 enzyme that triggers inflammation and contributes to pain in arthritic joints.

How Long Does Deramaxx Stay in Dog's System?

The medicine remains in the dog's system for 24 hours.

Does Deramaxx Make Dogs Sleepy?

Deramaxx leading to drowsiness is not common. If your think your dog shows signs of lethargy, then it is a symptom of toxicity and a sign of a potential overdose.

Deramaxx overdose has a severe effect on the dog's kidneys and liver. Contact your veterinarian immediately if you see any signs of overdose.

How Long Before Deramaxx Kicks in?

Doramaxx takes one to three hours after ingestion to start working. Prolonged usage of the drug shows more signs of clinical effectiveness.

Is There a Generic Form of Deramaxx?

Deramaxx is the brand name for the drug with the generic name Deracoxib. Deracoxib is a Nonsteroidal Anti-Inflammatory Drug (NSAID) of the coxib class.

How Much Deramaxx Can a Dog Take?

If your dog is suffering from osteoarthritis (OA) pain and inflammation, the daily dose is .45 mg to .91 mg/lb. If your dog is diagnosed with post-operative orthopedic pain, then the dose is 1.4 mg to 1.8 mg/lb daily

Please contact your veterinarian for the exact dosage as may be fit for your dog's conditions. Deramaxx tablets are available as 12mg, 25 mg, 75 mg, and 100mg tablets depending on the strength needed.

Is Deramaxx Dangerous to Dogs?

Deramaxx or Deracoxib is an FDA-approved drug and has proven to be effective among dogs. Deramaxx should not be used in dogs:

  • with hypersensitivity to sulfonamides
  • that are allergic to it or drugs like it
  • that have bloody stools or vomit
  • that have a loss of appetite
  • that have heart complications, liver dysfunction, or kidney disease
  • that are dehydrated or are predisposed to dehydration
  • that are breeding, pregnant, or nursing

Deramaxx or Deracoxib should be used with caution in dogs:

  • that have or have had stomach ulcers
  • that are taking diuretics (e.g., furosemide)
  • that are geriatric
  • that have a bleeding disorder
  • that have heart disease
  • that use other NSAIDs or corticosteroids

Please consult their veterinarian immediately if your pet reacts to the medication. While consulting, inform him about the dog's ailments if it has any of the above.

Can I Give My Dog Deramaxx With Other Drugs?

Please consult your dog's veterinarian before administering any drugs. Inform him if your dog is on any medication, like any other NSAID, steroids, over-the-counter allergy, or cold medicine.

It is advisable to avoid any negative interactions with any other drugs, which can lead to additional side effects or reactions. Your dog's veterinarian may conduct a physical examination and seek their medical history.

What Are the Side Effects of Deramaxx in Dogs?

Side effects of Deracoxib in dogs, like other NSAIDs, might occur affecting the gastrointestinal tract, such as

  • Vomiting or diarrhea,
  • Decreased appetite,
  • Blood in stool or urine, and
  • Weight gain or loss.

There are other adverse reactions your dog can experience. Contact your veterinarian immediately if side effects mentioned below are seen:

  • Bloody vomit,
  • Abdominal pain,
  • Yellowing of eyes,
  • Skin afflictions (e.g., pruritus or unordinary bruising),
  • Color changes,
  • Lethargy
  • Decreased activity, and
  • Behavioral changes (e.g., aggression, changes in drinking or urination habits, etc.).

Digestive, kidney, or liver effects can also occur.

Are There Long-Term Effects of Using Deramaxx for Dogs?

Researches suggest there is no association between the length of Non-Steroidal drug administration you give your dog and the risk of increasing incidences of side effects.

Most side effects that do occur appear within two to four weeks.

What Is the Difference Between Deramaxx and Rimadyl?

There is no difference between Deramaxx and Rimadyl, both are extremely hard on the kidney and liver. Both are Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) approved by the FDA to relieve dogs of postoperative pain and inflammation.

Concluding Thoughts

The most important thing that you should know about Deramaxx is its power to relieve pain, inflammation, and suffering from arthritis, osteoarthritis, and postoperative procedures. Dog owners want to see their senior dog act like a happy puppy again!

DISCLAIMER: FDA law restricts Deramaxx only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if it's a good idea to treat all of the animals in your household to control intestinal parasites.

  • Elanco Animal Health Brand
  • Arthritis & Pain Pharmacy
  • Elanco Animal Health Manufacturer
  • Beef Flavor
  • Senior Life Stage
  • Oral Application
  • Dog Pet Type

Deracoxib
How to Use This NSAID to Control Inflammation in Dogs?


Overview 

Deracoxib helps get rid of the pain that pets can get after surgery. This medication is a nonsteroidal anti-inflammatory drug with a proven record for easing the pain associated with dental and orthopedic surgeries. You can even find its abundant use in the treatment of osteoarthritis. Deracoxib is also used to treat painful conditions relating to injuries.


Special Precautions

It is advisable not to use the medication for dogs that have allergies to a particular set of medication like aspirin or any other NSAIDs, nursing, pregnant, or breeding, blood in stools, vomiting blood, dehydrated or have a chance of dehydration, lacs appetite, kidney disease, etc. 


Caution is advisable for dogs with a bleeding disorder, stomach ulcers, diuretics, old, heart disease, etc. It is advisable to seek help from your veterinarian to tackle the medication such dogs.


Mechanism of Action

Being a member of the coxib class of NSAIDS, Deracoxib inhibits the production of 6-keto PGF1 and PGE1 by way of its impact on prostaglandin biosynthesis with inhibitory effects. COX-2 mediated PGE2 production inhibition by Deracoxib takes place in dog blood. The inhibition of COX-1 does not occur by deracoxib’s effects at a dosage of 2 to 4 mg per kg body weight per day. It is based on the studies done using cloned canine cyclo-oxygenase. Within two hours of giving deracoxib to your dog, 90% of the peak plasma levels and bioavailability of course is of older drug administration. More than 90% of Deracoxib is protein-bound in the serum. 


The metabolization of Deracoxib takes place in the liver and gets excreted via your dog’s feces as a whole compound or in any form of its four major metabolites. The half-life period of Deracoxib occurs after about three hours of its ingestion in the pet's body. However, there can be longer effectiveness of the medication observed among the pets.  


Known Drug Interactions

Hypersensitive dogs should not have Deracoxib for any other NSAIDs. It is also critical to maintaining the prescription to avoid giving other NSAIDs with Deracoxib like Aspirin, Meloxicam, Firocoxib, Carprofen, and Etodolac.


Brand/Generic Equivalents
Deramaxx

Deramaxx is an anti-inflammatory and effective pain-relieving medication prescribed for veterinary use and is restricted to use in dogs alone. Being a drug of coxib class, Deramaxx forms an active remedy in treating pain and inflammation related to osteoarthritis, post-surgery pain, and other such cases of chronic pain management. Deramaxx is non-steroidal and possesses anti-inflammatory and analgesic functions. This treatment of oral medication restricts the fusion of certain classes of compounds, which eventually help control or suppress the pain and inflammation in the animal. The medication is available by prescription and comes in beef-flavor chewy tablets, which any dog would readily accept.

The use of Deramaxx can affect the digestive system, kidneys, or liver; pets can display vomiting, diarrhea, color change or blood in stool or urine, decreased appetite, and behavioral changes. These symptoms are usually mild, but should be taken seriously; consult a veterinarian immediately if they occur. There may also be drainage or oozing at the surgical site, when Deramaxx has been taken to control postoperative pain.

The medication has to be used only by prescription and should be administered only in dogs. If the animal has had allergic responses to the medication in the past, it is advised to refrain from its use. Also, do not use the medicine in animals that are suffering from dehydration, kidney complications, and heart or liver problems. The medicine has a tendency to interact with NSAIDS. Do not try the medicine in nursing or breeding animals as well as use it with caution in animals that are hypersensitive to sulfonamides. Moreover, the medicine is to be used only in animals that weight four pounds or more.

The medication can bring about side effects in certain animals that may include extreme bowel movements, vomiting, anorexia, blood tints in stools and discharge from the affected area. These complications might also occur in the event of an overdose of medication.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Administer Deramaxx at the veterinarian prescribed dose, once daily for arthritis pain, or once prior to operative procedure then daily up to 7 days.

When prescribed for osteoarthritis related pain and inflammation use 0.45-0.91mg/lb once in a day or as required. In case of post-surgical orthopedic pain control stick to 1.4-1.8mg/lb daily once. In either case, make sure the duration does not exceed a week. The medication can be provided with or without food.

Store at room temperature in a tight, light resistant, childproof container; do not expose to high heat.

Deramaxx is manufactured by Elanco Animal Health

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