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Amitriptyline is a prescription antidepressant that helps modify behavioral problems in dogs and cats such as separation anxiety, inappropriate urination, and obsessive-compulsive grooming and scratching. Amitriptyline also works to lessen nervous anxiety.… [+]
Side effects do not generally occur, but may include weight gain (in cats), drowsiness, dry mouth (and other symptoms resulting from the drug's function as an antihistamine), loss of appetite, increased heart rate, urine retention, vomiting, and diarrhea. There may be an increase in excitability.
Overdosing can have severe consequences for the heart, and should be treated immediately.
Amitriptyline can be administered either orally or by injection. Dosage is as prescribed by your veterinarian (generally, an oral dose is between 0.5 and 2 mg per pound once or twice a day for dogs, and between 2 and 10 mg per cat once daily for cats).
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