Acepromazine for Dogs and Cats
Acepromazine maleate is a widely used pet medication in veterinary medicine. It is known for its antipsychotic properties and calming effects on anxious animals. Acepromazine primarily affects the central nervous system and is effective in managing a variety of symptoms in dogs and cats.
Benefits and Uses
Acepromazine acts by blocking serotonergic receptors at subcortical levels, making it an effective antipsychotic agent. It is commonly used to manage both productive and unproductive symptoms in animals, such as anxiety and stress, especially during stressful events like visits to the veterinarian or travel. This medication is particularly beneficial for young animals and giant breeds, which can be more sensitive to stressful situations. Acepromazine in lower doses can effectively calm anxious animals without causing significant adverse effects.
Mechanism of Action
Acepromazine's principal value lies in its ability to attenuate extrapyramidal side effects, which are common with many antipsychotic agents. It possesses slight antihistaminic and weaker peripheral anticholinergic activity, reducing the risk of causing anticholinergic symptoms like dry mouth and reflex tachycardia. This tertiary amino compound affects multiple organ systems, providing a broad range of therapeutic effects. The central nervous system is primarily influenced, with acepromazine acting as a blocking agent at subcortical levels. Its ganglionic blocking action further contributes to its effectiveness in managing various symptoms.
Administration and Dosage
Acepromazine is available in tablet and injectable form, making it convenient for use at home or in a hospital setting. The effects of acepromazine can be seen shortly after administration, making it suitable for situations requiring immediate intervention. While it is primarily used in animals, acepromazine has also been used in humans for its antipsychotic properties, though it should be used with caution due to the potential for adverse effects. Lower doses are recommended to minimize the risk of side effects and ensure the animal's safety and well-being.
Adverse Effects and Considerations
Acepromazine should be carefully monitored, especially in animals with heart disease, as it can cause low blood pressure and other cardiovascular issues, such as sinus tachycardia. It should be used with caution when combined with other medications to avoid exacerbating adverse effects. In high doses, acepromazine can lead to adverse effects, including sexual dysfunction and weight gain. The effects of acepromazine on body temperature should also be considered, as it can influence thermoregulation in animals.
Additional Considerations
Acepromazine is part of a class of medications that include atypical antipsychotics, which are known for their broad spectrum of action on the central nervous system. The effects acepromazine provides are essential for maintaining the well-being of anxious animals, particularly during stressful events. Food reduces irritation at the injection site, making it easier for animals to tolerate the medication.
Acepromazine is a versatile and effective medication for calming anxious animals and managing various symptoms in dogs and cats. Its ability to act on the central nervous system primarily, coupled with its antipsychotic properties, makes it a valuable tool in veterinary medicine.
Your Complete Guide to Acepromazine for Dogs and Cats
What Is Acepromazine for Dogs and Cats?
Acepromazine or Acepromazine maleate is a chemical tranquilizer or sedative. Acepromazine can be used before anesthesia to restrain your dog or cat and prevent them from hurting themselves or the surgeons. Acepromazine for cats and dogs can be used to avoid motion sickness in your pets.
If your pet has issues with trimming their nails and reacts very adversely to being taken to the grooming salon, Acepromazine for dogs can be used to calm them down.
How Does Acepromazine for Cats and Dogs Work?
Acepromazine for dogs and cats is a neuroleptic agent that is used by vets for cats, dogs, and even horses. This class of chemicals is called Phenothiazines and works by suppressing dopamine levels in the brain and repressing some parts of the reticular activating system. Usually, it is processed by the body quickly and is excreted with urine.
Besides being a sedative, Acepromazine for cats and dogs can be used to treat allergic reactions and as an antispasmodic. Additionally, this medicine is used as an antiemetic, an anticholinergic, and blocks alpha-adrenergic properties. Anticholinergic means that it surpasses the functions of the parasympathetic nervous system.
This helps your anxious cat or dog to calm down and maintain composure. An antiemetic means any substance that prevents your dog or cat from vomiting. This is why it is used frequently in cases of motion sickness. Acepromazine for dogs and cats decreases blood pressure in your pets and slows down their heart rate.
What Is the Acepromazine Dosage for Dogs and Cats?
When giving your pet Acepromazine for cats and dogs, you should follow your vet's recommendations. Surprisingly, the Acepromazine dose for cats and dogs decreases inversely to the animal's size or weight. This means larger animals can get smaller doses. For dogs, the dosage is 0.25 mg/lb of body weight.
The Acepromazine dose for cats and dogs that your vet prescribes for your pet can vary depending on the condition being treated, the severity of the situation, and your pet's health. Please follow your vet's guidelines for how much of this medicine to give to your pet.
Are There Any Precautions I Should Take When Giving Acepromazine for Dogs and Cats?
You should ensure that you give this medication before the anxiety-causing event. It has been observed that the effects of the medicine are more pronounced when given before the situation your pet needs it for occurs. You can give this with or without food.
You should not give this to animals who are in shock or have just gone through a traumatic event. Animals who are dehydrated or anemic should not be given this medicine. This medicine is to be used with caution in senior cats and dogs, especially those with liver or heart disease.
If your cat or dog has a history of epilepsy, you should not give them this medicine. Animals who are injured, under treatment for tetanus, pregnant animals, and lactating animals should not be given Acepromazine. Acepromazine is problematic in dogs who have a history of strychnine poisoning.
In dogs, giant dog breeds and Greyhound dogs have been shown to have a sensitivity to Acepromazine. On the other hand, if you have a terrier, you might need a larger dose. All brachycephalic or short-nosed dog breeds are more prone to the heart-related side effects of this drug.
What Are the Acepromazine for Dogs Side Effects?
When you give your dog or cat Acepromazine, you might notice that their heartbeat has slowed down or they have hypotension. Cats have an increased risk of cardiovascular collapse, though dogs are prone to cardiovascular side effects. You might notice your pet has pale gums, a reduced pulse, and they might collapse suddenly.
While it is rare, Acepromazine can sometimes be fatal when used in conjunction with anesthetics. Another extremely rare side effect is penile paralysis in horses.
Frequently Asked Questions
-
Is This Safe to Give to All My Animals?
This drug is safe to use on horses, dogs, and cats. You should not give Acepromazine to any animals without a vet's supervision. This drug works on animals' sensitive nervous systems, and only your vet will be able to tell you the correct dosage you need to give to ensure your animal's safety.
-
How Should I Store This?
You need to store Acepromazine for cats and dogs away from any light. Ensure that the tablets are in an airtight container and are not exposed to extreme temperatures. Otherwise, the drug can lose its efficacy and become unstable.
-
Are There Any Drug Interactions I Should Know?
Acepromazine can cause reactions when combined with antacids, anti-diarrhea medicine, acetaminophen, dopamine, and fluoxetine, among others. If your dog is on long-term medication or if you give them over-the-counter drugs or supplements, make sure your vet knows before starting Acepromazine.
-
What Will My Vet Do if My Dog or Cat Suffers From Side Effects?
If your pet has eaten too much of this medicine, your vet is likely to pump the stomach and empty its contents. This takes the drug out of your pet and prevents their bodies from absorbing it. If your pet suffers seizures from Acepromazine, your vet will likely use barbiturates or diazepam to help them recover.
-
Does This Need a Prescription?
Acepromazine is a regulated drug as it has tranquilizing properties. You need a vet's prescription to buy it. Vet prescriptions can expire, so you will need an updated one to purchase if you have an old prescription.
Acepromazine is the generic alternative to PromAce.