Using Clomipramine Hydrochloride - Behavior Issues

Clomipramine is used in the treatment of obsessive-compulsive disorders in dogs such as tail chasing, excessive grooming, acral lick dermatitis, and separation anxiety like destructiveness, excessive vocalization, loss of toilet control etc. For cats, the drug is used to treat urine spraying in sterilized and female cats.

Certain precautions must be taken while the pet is being treated with Clomipramine. Animals suffering from liver impairment should be cautiously monitored with suitable blood tests while under medication. Clomipramine also has the possibility to interact with different kinds of medications including cimetidine, monoamine oxidase inhibitors and antithyroid medication. The most commonly found effects of clomipramine are inappetance (not eating enough), sedation and increased heart rate.

Do consult the veterinarian before administering the medication. The usual canine dose of clomipramine is 1 to 1.5 mg per pound (2 to 3 mg/kg) twice daily. The feline dose of clomipramine is 0.25 to 0.5 mg per pound (0.5 to 1 mg/kg) once daily.