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Methylprednisolone belongs to the class of drugs known as glucocorticoids. It is an anti-inflammatory synthetic glucocorticoid used in the treatment of different allergic reactions and inflammatory diseases. It is also found to be effective in the treatment of various endocrine and rheumatic disorders, collagen diseases, dermatologic diseases as well as ophthalmic and respiratory diseases.This anti-inflammatory steroid can be injected in dogs to treat lick granuloma condition. In cats, it effectively cures feline bronchial asthma, feline rodent ulcer, feline inflammatory bowel disease, flea allergy dermatitis and military dermatitis. Methylprednisolone is also effective in treating several autoimmune diseases of the skin and hemolytic anemia.
Do not administer Methyprednisolone in animals suffering from ailments like glaucoma, Cushing’s syndrome and diabetes. When used in combination with non-steroidal anti-inflammatory drugs [NSAID’s] like aspirin, methylprednisolone can cause adverse effects and therefore do not administer this medication along with these drugs. Avoid administering the drug to animals with known allergy to glucocorticoids. Refrain from using it on pregnant and breeding animals as it can lead to congenital anomalies and even fetal death. The medication is not suitable for animals with corneal ulcers, high blood pressure or congestive heart or kidney failure.
Strictly follow the instructions of a veterinarian when administering methylprednisolone. Each methylprednidolone tablet contains 4mg methylprednisolone. Dosage depends on several factors like severity of the condition, the mode of administration and the like. The same dosage pattern is followed for cats and dogs and this usually ranges from 0.5 mg per pound (1 mg/kg) to 15 mg per pound (30 mg/kg). Divide the total dosage into equal parts and administer every 6 to 10 hours apart. The veterinarian might increase or cut down the duration of treatment as per the response to the medication and appearance of adverse effects. Avoid increasing the dosage, or stopping the treatment without consulting a veterinary expert.
Medrol® (Upjohn), Depo-Medrol® (Upjohn) and generics
The most frequently noted side effects include vomiting, behavior modification, lethargy, increased water intake, increased frequency of urination, increased appetite and panting. Prolonged usage can induce symptoms of hair loss, skin thinning and pigmentation, muscle weakness, diarrhea and diabetes related complications.
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