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May 22, 2013
Hydroxyzine is an antihistamine used for the treatment of allergies, itching, atopy, and dermatitis in cats and dogs. The antiemetic property of the medication reduces nausea, while the anxiolytic property aids the treatment of anxiety. Hydroxyzine comes in two formulations: hydroxyzine pamoate and hydroxyzine hydrochloride salts. The active ingredient in the medication, hydroxyzine, works by inhibiting the effect of histamine on H1 receptors.
Hydroxyzine should not be used in animals with hypersensitivity, allergy to antihistamine, glaucoma, high blood pressure, lung disease, heart disease, and prostate enlargement. Hydroxyzine is not recommended for use in pregnant or nursing animals. Extreme caution is required when using Hydroxyzine in pets with urinary obstruction and intestinal obstruction. Hydroxyzine should not be used with drugs like barbiturates, tranquilizers, and Epinephrine as negative interactions have been observed. Precaution is required when given with CNS depressant drugs like Acepromazine, monoamine oxidase inhibitors (MAOIs) like Selegilene, and preventic collars and drugs used for wheezing such as Theophylline, Epinephrine, or Ephedrine. Store Hydroxyzine at room temperature, away from excess heat and moisture.
Hydroxyzine is a pet prescription drug and is available in tablets, capsules, and syrup. The drug is available in 25 mg/ml and 50 mg/ml injectable concentrations. The standard dosage for dogs is 1 mg/lbs (2 mg/kg) 2 – 3 three times a day orally. In cats, the dosage is 0.5 – 1 mg/lbs (1 – 2 mg/kg) or 5 – 10 mg/cat every 8 – 12 hours orally. The duration of the treatment depends on the clinical condition of the pet. It is recommended to continue the treatment, even if the pet shows signs of recovery.
The commonly observed side effects of hydroxyzine include sedation, lack of coordination, vomiting, lethargy, weakness, increased thirst, lack of appetite, and diarrhea. Contact your veterinarian if your pet starts showing or experiencing any signs of allergic reaction (difficulty breathing, hives, swelling of the face, tongue, lips, or through ) while taking Hydroxyzine.
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