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September 16, 2013
Gabapentin is an anticonvulsant medication that works by enhancing the release and action of GABA (gamma-Aminobutyric acid), which is a chief inhibitory neurotransmitter that plays a major role in regulating nervous impulses, which, in turn, are a major cause of seizures. Usually taken in a cocktail of other anticonvulsant medications, Gabapentin is a key ingredient for many pets trying to live with epilepsy.
Since this drug is designed for use in humans, its use in pets is considered “extra-label,” but can be legally prescribed by a veterinarian. However, because of this, its usage in pets has not been extensively studied, meaning that this drug should be taken with caution, and possibly at a reduced dosage.
Gabapentin should not be taken with antacids, since the bioavailability of gabapentin is decreased when taken with antacids. Taking with Hydrocodone might increase the efficacy of gabapentin, along with adverse side effects associated with gabapentin. Taking with morphine can increase gabapentin levels.
Since gabapentin is an extra label veterinary medication, you should follow your vet’s specific direction, since dosages can vary depending on your pets size, species, breed, weight, and age.
Sudden withdrawal should be avoided, as this can cause adverse effects. While specific veterinary studies are not available, humans taking gabapentin experience CNS depression, sedation, dizziness, sleepiness, and peripheral edema.
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