Clomicalm
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At a Glance
Clomipramine Hydrochloride is a tricyclic antidepressant that restores hormone (e.g., serotonin) balance in the brain
Treats obsessive compulsive disorder (OCD), separation anxiety, excessive barking, aggressive and destructive behavior, inappropriate elimination, and other anxiety-related behaviors
Oral, beef-flavored tablet given twice daily
Observe therapeutic effects in just two weeks

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Rated 4.5 out of 5 by 21 reviewers.

  • Clomacalm
    This medication has helped my anxious dog tremendously. It does not make her lethargic it just clams her nerves so she can enjoy life instead of being afraid of everything. Pet Plus makes it easy to order - thanks! by on 11/17/2019
  • Didn't help with anxiety
    This pill didn't particularly help with my dog's anxiety. She still had her OCD tendencies of licking the floors. Behaviorally, the only difference I could tell was that she was slightly tired and less playful. by on 07/20/2018
  • Clomcalm
    I can't even begin to describe the difference in my dog since taking this ,she is a different dog . by on 05/17/2018
  • Helpful
    Male JR helped with separation anxiety which resulted in him marking everywhere in the house. Has helped tremendously. Hasn't affected diet, personality etc. by on 03/31/2018
  • Relief for our rescue Border Collie
    We rescued a young, male Border Collie who had been on his own for at least 4 -5 months (as tracked thru Facebook by the rescuing organization). Obviously full background information was unavailable, but it was apparent he had spend time with a loving family who taught him obedience and cared for him. Still, by the time we adopted him he also had acquired a number of anxiety issues. He had been returned twice to the shelter and they indicated that if he did not work out in our home - if his anxieties were too severe and complex then he would most likely be humanely euthanized. In collaboration with our vet, we worked with him for 6 months before we finally opted to try Clomicalm. It was really the last option available. It took 2 weeks for the medication to take full effect. The difference is night and day! We did have to scale the dosage of the pm pill down, but he is finally acting like a well adjusted Border Collie - still full of energy, eager to learn and to please. The vet tech/canine behaviorist at the vet's office was amazed. Occasionally I will get distracted and forget to give our pup his pill. He knows when it is due! He will start pawing at me and drooling - we administer in peanut butter and he is asking for the treat as much as wanting to calm down. This is an expensive option and will limit us from being able to add to our four-footed family, but we are pleased with the outcome. Clomicalm works for our pup! by on 06/11/2016
  • This product seems to be effective
    I started my 2 year old, shelter rescued dog on Clomicalm almost 2 weeks ago. I first started giving 1 tab 1x/day, but now give 1/2 tab 2x/day. The first day after it seemed to have worn off, my dog showed aggression towards my other dog, but her overall behavior seems to be improved with the 2x/day. by on 05/01/2016
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