Understanding Feline Hepatic Lipidosis: The Silent Killer in Cats How to Protect Your Cat from Feline Hepatic Lipidiosis

Understanding Feline Hepatic Lipidosis: The Silent Killer in Cats

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Feline hepatic lipidiosis is often called a silent killer because the disease doesnโ€™t cause any visible symptoms until it reaches an advanced stage. Learn more about its diagnosis and treament.

Feline hepatic lipidosis, also known as fatty liver disease, is a serious and potentially life-threatening condition that affects cats. It occurs when the liver becomes overwhelmed with fat, leading to inflammation and damage to liver cells. 

This condition is often referred to as the "silent killer" in cats because it can progress rapidly and silently, with few visible symptoms until the disease has advanced. In this article, we will delve into the causes, symptoms, and treatment options for feline hepatic lipidosis, as well as ways to prevent this condition in your furry feline.


There are several factors that can contribute to the development of feline hepatic lipidosis. The most common cause is a sudden and significant decrease in food intake, often due to an underlying illness or loss of appetite. When a cat is not consuming enough calories, the body begins to break down fat stores as an energy source. This leads to an accumulation of fat in the liver, eventually leading to hepatic lipidosis.

Other potential causes of hepatic lipidosis in cats include:

  • Chronic kidney disease

  • Diabetes

  • Inflammatory bowel disease

  • Pancreatitis

  • Hyperthyroidism

  • Certain medications

  • Stress

  • Obstruction in the intestine or stomach

It is important to note that any cat can develop hepatic lipidosis, but it is more common in overweight or obese cats who already have a higher amount of fat stored in their bodies.


Feline hepatic lipidosis can be a difficult condition to detect in its early stages because it often does not produce visible symptoms. As the disease progresses, however, the following symptoms may develop:

  • Loss of appetite

  • Weight loss

  • Vomiting

  • Diarrhea

  • Constipation

  • Lethargy

  • Jaundice (yellowing of the skin and whites of the eyes)

  • Abdominal pain

If you notice any of these symptoms in your cat, it is important to seek veterinary care as soon as possible. The earlier the condition is diagnosed and treated, the better the chances of recovery.

It is also important to remember that cats are masters at hiding illness, so even if your cat appears to be acting normal, it is always a good idea to consult your veterinarian if you have concerns about your cat's health.


To diagnose feline hepatic lipidosis, your veterinarian will perform a physical examination and take a medical history. They may also recommend the following diagnostic tests:

  • Complete blood count (CBC) to evaluate overall health and check for anemia and infection

  • Biochemistry panel to assess liver function and look for evidence of liver damage

  • Urinalysis to assess kidney function and look for underlying problems such as urinary tract infection or diabetes

  • Thyroid hormone level test to check for hyperthyroidism

  • X-rays or ultrasound to visualize the liver and check for abnormalities

  • Fine needle aspiration or biopsy of the liver to confirm the diagnosis and assess the severity of the disease

In some cases, additional testing may be necessary to determine the underlying cause of hepatic lipidosis.


The primary goal of treatment for feline hepatic lipidosis is to restore the normal function of the liver. This typically involves a combination of medical therapy and supportive care.

Medical therapy may include:

  • Fluids to correct dehydration and electrolyte imbalances

  • Nutritional support to help the cat regain weight and provide essential nutrients for liver health

  • Medications to control vomiting and diarrhea, as well as to reduce inflammation in the liver

  • Antibiotics, such as Clavamox, to treat or prevent infections

  • Medications to control underlying conditions, such as diabetes or hyperthyroidism

Supportive care may include:

  • Hand feeding or placement of a feeding tube to ensure that the cat is getting enough calories and nutrients

  • Close monitoring of the cat's progress and adjustments to the treatment plan as needed

  • Regular blood work to monitor liver function and check for any complications

It is important to follow your veterinarian's treatment recommendations closely and to bring your cat back for follow-up care as directed. With proper treatment, many cats can make a full recovery from hepatic lipidosis.

Preventing Feline Hepatic Lipidosis

The best way to prevent feline hepatic lipidosis is to ensure that your cat is getting the proper nutrition and maintaining a healthy weight. This includes:

  • Feeding a high-quality diet appropriate for your cat's age and lifestyle

  • Providing chews and treats to support liver function and detoxification

  • Providing fresh water at all times

  • Monitoring your cat's food intake and weight

  • Providing regular exercise to maintain muscle mass and prevent obesity

  • Seeking veterinary care for any underlying health conditions that may affect appetite

By following these recommendations, you can help protect your cat's liver health and reduce the risk of hepatic lipidosis.

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