Allopurinol
Allopurinol
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At a Glance
Metabolizes in just 2 hours
Easy to administer tablet for the treatment of bladder stones
Dissolves pre-existing stones

Allopurinol

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At a Glance
Metabolizes in just 2 hours
Easy to administer tablet for the treatment of bladder stones
Dissolves pre-existing stones

Allopurinol is a fast-acting prescription oral tablet, intended to prevent and dissolve urate bladder stones. Allopurinol is a xanthine oxidase inhibitor, which means it inhibits the production of uric acid, preventing the build up of the crystals in the urine that cause bladder and kidney stones.

Allopurinol works by preventing the conversion of protein purines to uric acid. While Allopurinol prevents bladder and kidney stones, it can also dissolve stones that have already formed, and also treats infection due to the blood parasite Leishmania.

Allopurinol is the generic alternative to Zyloprim.

What Are the Side Effects of Allopurinol in Dogs?
Answer

Allopurinol is a safe, veterinary-recommended, and effective medication for dogs. It helps prevent bladder and kidney stones in dogs. It dissolves existing urate bladder stones as well. While the drug is considered safe for dogs, it might cause side effects, such as diarrhea, gastrointestinal distress, dizziness, and drowsiness. Also, it can trigger symptoms of an allergic reaction, including facial swelling, rashes, blood in the urine, painful urination, nausea, and vomiting. It's important to consult a veterinarian if your notice any unusual symptoms or behavior in your dog after administering allopurinol. Additionally, make sure you inform them about any other medication your dog is currently taking.

Will Allopurinol Hurt My Dog?
Answer

Allopurinol is a powerful xanthine oxidase inhibitor that helps prevent and control urate bladder stones in dogs. It controls uric acid production, thus eliminating the chances of crystal formation in your dog's kidneys and bladder. As long as you follow your vet's instructions regarding the dosage and timing of administering allopurinol, the medication won't hurt your dog. However, it's important to watch out for signs of allergic reactions, such as swelling of the face and tongue, excessive vomiting, and nausea. Also, allopurinol is known to have drug interactions with specific medications, such as amoxicillin, ampicillin, warfarin, azathioprine, etc. If your dog is taking any of these medications, don't forget to let your veterinarian know before they prescribe allopurinol.

Can Cats Take Allopurinol?
Answer

Yes. Allopurinol can be administered to both cats and dogs for the treatment of kidney and bladder stones. It inhibits uric acid production and prevents the formation of crystals in the urine. Side effects or allergic reactions to allopurinol are uncommon in cats and dogs. Nevertheless, it's always a good idea to consult your vet before administering the medication to your cat.

Is There an Over the Counter Substitute for Allopurinol?
Answer

Allopurinol is a prescription medication that isn't sold over-the-counter in the U.S. Currently, there are now known OTC substitutes for allopurinol. Make sure you consult your vet before considering any allopurinol substitutes for your dog.

Can Allopurinol Cause Bladder Stones?
Answer

No. Allopurinol is a xanthine oxidase inhibitor. That means the drug minimizes uric acid production and thus, helps prevent the formation of crystals in urine. That's the reason allopurinol is used for the treatment of bladder and kidney stones in dogs. Allopurinol can also be given to cats. However, if your dog exhibits any signs of chronic kidney disease or bladder stones, it's always a good idea to consult your vet before administering allopurinol.

Which Is Better - Colchicine or Allopurinol?
Answer

Both allopurinol and colchicine can be used for the treatment of inflammation and pain resulting from gout attacks. However, long-term use of colchicine can result in blood disorders. On the other hand, allopurinol works by inhibiting uric acid production and crystal formation. That makes allopurinol a safer and more effective choice for preventing and dissolving uric acid crystals and bladder stones.

Is There Anything Better Than Allopurinol?
Answer

Allopurinol is a generic alternative to Zyloprim. It's a potent medication that treats urate bladder stones and gout attacks in dogs. While you'll find a few similar medications on the market, allopurinol is more effective. Also, adverse reactions to allopurinol are uncommon in dogs. It is, however, always important to talk to your vet before giving the medication to your dog.

Does Allopurinol Damage the Liver?
Answer

Short-term use of allopurinol won't cause any damage to your dog's liver. The most common side effects include symptoms of gastrointestinal distress. However, if you administer allopurinol to your dog over a longer duration, it can cause acute liver injury. But the occurrence of such liver damage is extremely rare. Also, it's more likely in dogs with allopurinol hypersensitivity syndrome. Make sure you consult your vet before using long-term allopurinol treatment for your dog.

Allopurinol

Seek emergency veterinary aid if your pet experiences an allergic reaction such as, hives, difficulty breathing, swelling of the face, lips, tongue or throat, blood in the urine, pain when urinating, a rash, eye irritation, fever, chills or joint aches or severe nausea or vomiting. Consult veterinarian if your pet experiences upset stomach or diarrhea, dizziness or drowsiness or an acute attack of arthritis, or anything out of the ordinary.

Ampicillin or amoxicillin may increase the risk of rash development. Notify your veterinarian if your pet is being given a thiazide diuretic, azathioprine, drugs used to treat cancer, cyclosporine, warfarin or theophylline. Consult to your veterinarian before administering additional prescription or over the counter medications.

Administer Allopurinol to the exact specifications prescribed by veterinarian. Give Allopurinol orally with water and food.

Dogs

All Weights: 5mg per pound of body weight, once daily with food

Medication Guide: Using Allopurinol for Urate Stones in Dogs

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

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