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September 04, 2013
A macrolide antibiotic, azithromycin is used to treat bacterial infections caused by susceptible bacteria, ranging from ear infections, strep throat, pneumonia, typhoid, bronchitis, and sinus infections. It is mostly useful against gram-negative bacteria, but can be used to ward of a few gram-positive strains as well.
Azithromycin has been contraindicated for use in patients with a known sensitivity to macrolide antibiotics, taking cisapride, or have liver disease. Patients taking antacids may experience a reduced rate of absorption. Hepatic enzyme inhibitors may alter the metabolization of azithromycin. Sucralfate may decrease the effects of azithromycin, and cyclosporine might increase blood levels.
5-10 mg/kg orally once or twice a day for 1-5 days.
Azithromycin may cause vomiting, especially in large doses, and can cause damage to the liver. Local IV site reactions have been known to occur. Azithromycin is known to have a very long half life in the tissue in dogs and cats.
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