Click to zoom Tap and hold to zoom
Refills on File
Your pet {{refill.petName}} has {{refill.refillsRemaining}} refill{{refill.refillsRemaining>1?'s':''}} for ‘{{refill.options}}’ which will expire on {{refill.expiresOn}}.
{{refill.petName}}'s refills for this have expired on {{refill.expiresOn}}
At a Glance
Treats a variety of internal and external fungal infections
Treats serious fungal infections of the central nervous system (CNS) more effectively than many other antifungals
Has fewer side effects than most other antifungals


List Price:
{{list_price * quantity | currency}}
List Price:
{{list_price * quantity | currency}} {{(list_price + 0.01) * quantity | currency}}
List Price:
{{list_price * quantity | currency}}
List Price:
See price in cart Why we cannot show price
List Price: {{list_price * quantity | currency}}
25% OFF w/code: CARE25
PetPlus Price:
{{petplus_price * quantity |currency}}
PetPlus Price:
See price in cart Why we cannot show price
Sale Price:
{{sale_price * quantity|currency}}w/code {{siteCode}}
Your Price:
{{map_price + 0.01 | currency}} See price in cart w/code {{siteCode}} Why we cannot show price
{{petplus_savings_amount * quantity|currency}} ({{petplus_savings_percent}}%)
{{coupon_savings_amount * quantity|currency}} ({{coupon_savings_percent}}%)
Join PetPlus today and get this for {{intro_price_total|currency}} Why we cannot show price
Join PetPlus today and {{use_strict_map_rules?"see price in cart":"get this for a special price"}} Why we cannot show price

inlowout of stock
Get notified as soon as this becomes available
Thank you.
We will email {{notifyEmail}} when this is back in stock.
Recommended Alternatives:
Limit ( {{ selected_sku_data.cartLimit }} ) per customer. Orders for more than this may not be fulfilled.
Shipping is always free with PetPlus | Arrives in 1-3 days on average
Free shipping over $48* | Arrives in 1-3 days on average
Select Autoship options at checkout
At a Glance
Treats a variety of internal and external fungal infections
Treats serious fungal infections of the central nervous system (CNS) more effectively than many other antifungals
Has fewer side effects than most other antifungals

Frequently Bought Together

Total Price

Fluconazole is an antifungal medicine that is used to treat a variety fungal infections, including yeast infections. It is typically used to treat skin infections, and more intense fungal infections of the lungs and other organs. Fluconazole is often used in pets who have been unable to tolerate other types of antifungal medication. It is also used for difficult-to-treat fungal infections, such as those that have spread to internal organs.

Fluconazole is the Generic Alternative to Diflucan.
  • Skin & Coat Pharmacy
  • Anti-Fungal Pharmacy
  • Mature Adult Life Stage
  • Senior Life Stage
  • Adult Life Stage
  • Oral Application
  • Cat Pet Type
  • Dog Pet Type

Is human Fluconazole safe for dogs?

Fluconazole (brand name Diflucan) is commonly prescribed to prevent and treat various fungal and yeast infections in humans. While fluconazole is not FDA-approved for animals, it may still be prescribed by veterinarians for off-label use. Off-label use refers to the use of a medication in a manner that is not specifically approved by the FDA but is within the professional judgment of the veterinarian. Veterinarians may prescribe fluconazole off-label for dogs based on their knowledge and experience with the medication, as well as the specific needs of the individual animal. They may consider factors such as the severity of the fungal infection, the response to other antifungal medications, and the overall health condition of the dog.

What is Fluconazole 100 mg used for dogs?

Fluconazole, in a 100 mg dosage, is commonly used in veterinary medicine for the treatment of certain fungal infections in dogs. It is an antifungal medication that belongs to the class of drugs known as azoles. Fluconazole works by inhibiting the growth and spread of fungi by interfering with their cell membranes. Fluconazole can be used to treat systemic fungal infections that affect various organs and tissues in the dog's body, including the lungs, central nervous system, skin, and others. Cryptococcosis is a fungal infection caused by Cryptococcus neoformans or Cryptococcus gattii. Fluconazole is often used as part of the treatment regimen for this condition. Blastomycosis is a fungal infection caused by the organism Blastomyces dermatitidis. Fluconazole can be used as part of the treatment plan for this systemic fungal infection. Histoplasmosis is caused by the fungus Histoplasma capsulatum. Fluconazole may be prescribed as part of the treatment protocol for dogs with histoplasmosis.

Is Fluconazole better than ketoconazole for dogs?

Both fluconazole and ketoconazole are antifungal medications commonly used in veterinary medicine to treat fungal infections in dogs. However, their effectiveness can vary depending on the specific fungal infection being treated and the individual dog's response. Fluconazole is generally more effective against yeast infections, such as Candida species, and certain dimorphic fungi like Histoplasma. On the other hand, ketoconazole has a broader spectrum of activity and can be effective against a wider range of fungal species, including dermatophytes (ringworm) and some molds. Fluconazole is well-absorbed when taken orally and has good tissue penetration, including the central nervous system. This makes it particularly useful for treating systemic fungal infections. Ketoconazole, on the other hand, has variable oral absorption and may require administration with food to improve absorption. Ketoconazole has a higher potential for drug interactions compared to fluconazole. It can inhibit liver enzymes that metabolize many medications, which may lead to altered blood levels of certain drugs. Fluconazole has a lower propensity for drug interactions and is generally considered safer in this regard. Both fluconazole and ketoconazole can have side effects, including gastrointestinal upset, liver toxicity, and changes in hormone levels. However, ketoconazole has a higher incidence of adverse effects, particularly hepatotoxicity, compared to fluconazole.

How fast does Fluconazole work in dogs?

It can take some time to reach a stable blood level of fluconazole in the body, typically within one to two weeks of regular administration. This is because fluconazole has a relatively long half-life, meaning it remains in the body for a significant duration of time. While fluconazole may not provide rapid results, it gradually accumulates in the body over time, reaching therapeutic levels that can effectively combat the fungal infection. The timeframe for a noticeable improvement in symptoms can vary depending on factors such as the specific fungal infection, its severity, and the individual response of the dog.

Is Fluconazole an antibiotic?

No, fluconazole is not an antibiotic. It is an antifungal medication. Antibiotics are medications specifically used to treat bacterial infections. They work by either killing bacteria or inhibiting their growth. Examples of antibiotics include penicillin, amoxicillin, and ciprofloxacin. Fluconazole, on the other hand, belongs to a class of drugs known as azole antifungals. It is used to treat fungal and yeast infections by inhibiting the growth and spread of fungi. Fluconazole is effective against a variety of fungal species and is commonly used to treat conditions such as vaginal yeast infections, oral thrush, and systemic fungal infections.

Fluconazole 100 mg

The generic name for Diflucan, Fluconazole is a great way to get rid of a fungal infection, inhibiting the formation of the fungal cell wall, thereby resulting in cell death and the death of the organism. Working against infections under the nails, ringworm, blastomycosis, or cryptococcosis, this medication does a number on some dangerous fungal infections that might otherwise do damage to the skin, claws, brain, respiratory tract, bones, or other tissues. An โ€˜extra-labelโ€™ medication, it is not approved for use in pets by the FDA, but can legally be prescribed by a vet.

Fluconazole can interact with many other drugs. It is important to tell your veterinarian about any other medications, vitamins, or supplements your pet is taking before giving fluconazole to your pet. Do not give to pets who have liver disease or impairment. If your pet has kidney disease or kidney failure, discuss the risks versus benefits with your veterinarian before giving fluconazole. Do not give to pregnant animals or animals that are nursing unless your veterinarian says the benefits outweigh the risks. Do not give fluconazole to any pets who are sensitive or allergic to other "azole" antifungal medications, such as ketoconazole. If you have any concerns about this medication, talk with your veterinarian before giving it to your pet.

Keep out of reach of children and pets.

Vomiting, diarrhea, skin rashes, loss of appetite, increased liver enzymes, hepatic toxicity, or thrombocytopenia are all possible, but not common, side effects of fluconazole.

Fluconazole should never be used in patients with liver disease, and patients with kidney disease may need to have the intervals and dosage adjusted. Pregnant pets should only take fluconazole if the benefits outweigh the risks. Fluconazole might increase the risk of heart problems caused by terfenadine and astemizole. Anticoagulants might cause increased prothrombin times, and antidiabetic drugs might increase their serum levels, resulting in hypoglycemia, when taken with fluconazole. Fluconazole might inhibit the metabolism of cisapride, resulting in high plasma concentrations, which has been linked to fatal cardiac arrhythmias. Fluconazole might increase cyclosporine levels or plasma levels (when used with hydrochlorothiazide). Rifampin might increase the metabolism rate of fluconazole.

Dogs/Cats (All weights): Dosage and how frequently you will need to administer the medication depends upon the particular infection being treated.

Dogs -- 2.5 - 5 mg/kg orally or IV once a day, or 1.25 - 2.5 mg/kg orally or IV twice a day, for 8 - 12 weeks
Cats -- 2.5 - 10 mg/kg orally every 12 hours for 1 month

Follow your veterinarian's instructions.

Store at room temperature in child-proof containers.

Option UPC/SKU
100mg per tablet 368462102305

How to Order Prescriptions Online

1. Find the Right Product

Make sure it matches your pets prescription. Donโ€™t forget to compare the dosage for pills/capsules!

2. Add to Cart

Just like any other online store. Make sure the quantity matches whatโ€™s been prescribed by your vetinarian.

3. Tell Us About Your Pet and Vet

Answer some questions during checkout and weโ€™ll contact your vet and verify the prescription for you. You can also mail us the written prescription.

4. Thatโ€™s It!

If the prescription has any refills, processing your future orders for that medication can be expedited.

Related Articles

Blastomycosis in Cats: Causes, Symptoms, and Treatment

Recognizing and Treating Feline Blastomycosis

Read More
Fungal Pneumonia in Dogs: A Detailed Guide

What To Know About Fungal Pneumonia In Dogs

Read More
Phythiosis in Dogs: Causes, Symptoms, and Treatment

Recognizing and Managing Phythiosis In Dogs

Read More

Customer Reviews

Rating Summary 3 review(s)
5 stars
4 stars
3 stars
2 stars
1 star
3 / 5
* = required

New Product Review

Uploaded Image 1
Uploaded Image 2
Uploaded Image 3
  • {{error}}
Showing 1 - {{visible_reviews.length}} of {{total_reviews}}

This product has no reviews yet. Write a review.

Saved our cat's life!

Our cat started showing signs of improvement within a couple of weeks from his histoplasmosis. He has shown no signs of side effects. He will continue treatment for several months. Had to cut the pills in half though, because they didn't have 50mg pills.

BobTheCat recommends this item.
Was this review helpful? 0 0

giving for ring worm

After six weeks of treatment my dog has not got any better. Perhaps it takes a long long time to get better. I don't know

Vegas54 recommends this item.
Was this review helpful? 1 0

Did Not work for my Dogs Condition

This medication is not working for my Dog. No change in her condition after administering meds after 2 weeks. I still have 2 more weeks but I don't think it will work.

CocoB recommends this item.
Was this review helpful? 1 1

Page 1 of 1 1