Indications for Metoclopramide
Metoclopramide is classified under the drug group ‘anti-emetics’ or anti-vomiting drugs and is effective in the treatment of gastrointestinal disorders and managing vomiting in cats and dogs. It also helps in stimulating the stomach and intestinal motility. Metoclopramide also effectively treats and manages reflux diseases. Metaclopramide works by blocking the chemical dopamine in different parts of the brain and thus provides a central anti-vomiting effect. It works to stimulate the contraction of the stomach, and also of the upper portion of the small intestine. Another significant effect of this medication is that it increases the pressure at the lower esophagus, thereby preventing stomach acid from entering the esophagus. The medication can be administered in pets with gastroenteritis or kidney failure.
Precautions when using Metoclopramide
Refrain from administering the medication on animals with known hypersensitivity to the drug. Metoclopramide has a tendency to interact with drugs like cimetidine, tetracycline, insulin, diazepam, atropine and digoxin. Therefore, do not administer the medication if the pet is under treatment that involves any of these medications.
Side Effects of Metoclopramide
Metoclopramide can bring about side effects in some animals if used without the prescription of a veterinarian. At times, the side effects exhibited include changes in the behavior and mental states in cats. Anxiety and frenzied behavior is usually noted in some animals especially in cats. In certain cases, the medication can also cause symptoms of nausea, sedation and mild constipation.
Dosage for Metoclopramide
Dosage should be strictly as per veterinary instructions. The ideal dosage usually administered in animals is 0.1 to 0.2 mg per pound (0.2 to 0.5 mg/kg) every six to eight hours. The administration can be done orally, subcutaneously or intravenously. The ideal time for administration is half an hour prior to food. Continue the dosage and duration unless the animal shows any symptoms of adverse effect. Take care not to stop medication unless prescribed by the veterinarian.
Brand/Generic Equivalents of Metoclopramide