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Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.

Options Available: 5-10 lbs., 6 pack 10.1-20 lbs., 6 pack 20.1-40 lbs., 6 pack 40.1-60 lbs., 6 pack 60.1-120 lbs., 6 pack

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Rated 4.5 out of 5 by 158 reviewers.
Rated 5 out of 5by 3 birds, 1 stoneI like that I don't have to worry about separate meds for heartworm and fleas. It's expensive, but evens out when you combine other med costs. My dog's only gotten sick from it once, and I think it was because I gave it to her too late after she finished eating for the night. 07/22/2013
Rated 4 out of 5by Good for small dogsMy dog is under 5 pounds. With some of the flea medications, you need to be careful because they are "for under 20 pounds" and even so, some are too much for such a little dog. This medication is fine for her. It does make her a little lethargic but only for about 1 day. As far as I know, it works. I haven't had any flea issues. I think it's expensive but they all are these days. 07/20/2013
Rated 5 out of 5by Works wellI wish it were more palatable to our dog. She hates the taste. WILL NOT eat it, not even swallow it in small pieces. I have to pulverize it. She is usually a pretty good pill taker. (has to take 4 pills per day' just toss them onto the back of her tongue, and rub her throat and offer her a treat. However, nothing works with the Trifexis! PLEASE tell the company to make it more "dose easy"! 07/19/2013
Rated 4 out of 5by Trifexis works wellfrom Florida it is a definite asset other than the cost & the dogs HATE it , they take heartguard like a cookie, for the cost you have to become quite creative. not only my dogs my sister in law turned me on to trifexis & has the same trouble To get them to eat it! 07/16/2013
Rated 5 out of 5by Highly recommended.If it was in a chewy tab, my dogs would like it better, but I love the ease and the effectiveness of this product, I JUST CRUSH THE TABLETS IN THE PACKAGE, OPEN IT UP POUR OVER DRY FOOD AND THEN ADD A LITTLE WET FOOD TO MIX IT IN AND THEY EAT IT UP. I hated the flea products that you administer to there skin as I have a black lab with long thick hair and a vizla and they love water and never felt the products were as effective. 07/16/2013
Rated 5 out of 5by A good product!I live in a rural area and my dogs were constantly infested with fleas, despite using various flea products. Since I started Trifexus over a year ago, I have not seen 1 flea on either of them! 07/12/2013
Rated 5 out of 5by Love it!I live out in the country, and both my dogs were fighting fleas and ticks even with 3-4 week spot treatments and they both had hookworm. The first time I used Trifexis, they were both nauseated with the first dose and didn't digest the entire tablet, but I still noticed a reduction in fleas and stomach problems. They weren't as nauseated with the second dose. We are at two full months now, and I haven't seen a flea or tick in at least 4-6 weeks, and it doesn't even say anything about tick preventative. They are also both free of hookworms, and their skin is getting clearer from where they had been scratching. I love that this gives heartworm, flea, and intestinal worm treatments all in one product, and the cost is great compared to buying two or three different products. My vet recommended this to me because he uses it for his dog, and I would definitely recommend it to other people. 06/29/2013
Rated 4 out of 5by I have a minature schnauzer 16 lbs, have been giving it to her for about 2 years. The price continues to go up each time I buy a 6 month supply.Besides the price going up each time I buy, it makes her very itchy, so then I have to give her another pill to try to combat the itching (Temeril P), which makes it more expensive 04/23/2013
Rated 4 out of 5by Not one flea but....We have a mini dachshund. I added up the cost and this product was cheaper than having to buy all monthly products (heartgaurd, wormer, etc..) by around $5-$10. I don't have any problem with her taking it. It is a hard pill and with other products I have been known to roll cheese around it. However, the only issue thus far has been the itching. I thought at first she had fleas, then just dry skin but after reading up this product has a side affect of itching. She also got tapeworms so I'm assuming it doesn't protect against them. She mainly an indoor dog but on pretty days she spends a good dosage of outside time. 03/26/2013
Rated 3 out of 5by Expensive but EffectiveThis product is Effective. I have not seen a flea on my dog and we live in Florida. We will see when summer hits if it is truly repellent of fleas. I gave low ease of use because it is not chewable. I have to fight with her every month to take it. She smells it and cowers down. I cannot put it in cheese or meat because she won't eat it. I did however discover smothering it with peanut butter and then cheese works the best. It still requires a fight. Also, this is a very expensive pill and you cannot afford any monthly mistakes. I wish it was a little cheaper. It is definitely making me look for an alternative. 03/16/2013
Rated 4 out of 5by Very EffectiveMy Dachshund gets this produce once a month and it is VERY effective. Be careful to order the correct dosage because it is dangerous if you give a more powerful strength than needed. I recommend this product over Comfortis. Mo weighs 13lbs so she gets the one for dogs 10.1-20 pounds. Be sure to give your dog food when you give this product because it could possibly upset your pet's stomach. Mo eats it no problem, I don't even have to disguise it in a dog treat or break it up. 03/12/2013
Rated 4 out of 5by Great Heart Worm Medicine/Flea ProtectionHello Everyone, I have a 10 year old Golden Retriever now and my Vet recommended I put her on Trifexis and Front Line plus simply because I live in a wooden area that and she allergic to flea saliva bites. I been using Trifexis for nearly two years now and its a Great Preventive against worms and that fleas may carry. The reason I have it a Two bar on Ease of Use is because she will not chew it I have to kinda break it down is sections for her just for her to eat it. Plus You have to give your pet a meal before giving this medicine to them or other wise it upsets the stomach and will cause them to throw up. Other then that its a great product! Only Reason it got a four star from me is because its not a easy chew tablets for my dog. But, if anyone was to ask me on what type of flea/heart medication to put there pet on I would tell them to do Trifexis and Front Line plus because you will get double the protection and the Front Line Plus will protect your pet from Ticks!!! 02/28/2013
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