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Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.

Options Available: 5-10 lbs., 6 pack 10.1-20 lbs., 6 pack 20.1-40 lbs., 6 pack 40.1-60 lbs., 6 pack 60.1-120 lbs., 6 pack

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Rated 4.5 out of 5 by 158 reviewers.
Rated 5 out of 5by I think is too expensive. Most folks can't afford this for their pets & that's too bad because Our pet has not had worms,fleas,or ticks & that's grea It works great.Max has not tested positive for worms while on this medication. He has not had a flea or a tick on him While he has been on it either. 10/08/2013
Rated 1 out of 5by Not worth the moneyI have a 13Lb 3yr old pug. She is normally happy and energetic. I normally give her the plus version of a leading brand of topical flea treatment that protects against everything but heartworms. I thought to switch to this product so I would not have to administer an additional heartworm pill and I thought I was doing her a favor by not applying chemicals to her skin. I split the pill into quarters and mixed it with chicken. I could tell by the look in her face that she disliked it very much. She has been much less energetic since I gave her the pill five days ago. She is itchy and seems to pay more attention than ever to her genital area. So, now I don't have to give her a separate heart pill, but I have to worry about ticks, flea pupae, itching, lethargy, "licking of the genitals" and the guilt of giving her a large and distasteful pill. For the money, I expect better. I figure I can go back to the topical treatment and at least she is protected against ALL stages of fleas AND ticks, plus she does not mind the taste of the heart pill. 09/30/2013
Rated 5 out of 5by Great Product but...I LOVED this product only reason I stopped using it was cause it was NOT tested on breeding males which my dog is. But for the time I was using this product it did wonders for getting rid of the fleas kept the ticks down (we hike a lot). 09/16/2013
Rated 5 out of 5by Great product, totally works, and PetCareRx offers it at a great price!We've been using this product as well as PetCareRx for close to four years now and are extremely happy with the level of service and value. 09/05/2013
Rated 4 out of 5by GOOD ALL IN ONEThis is a good all in one flee plus heart guard. It did well for one of my dogs, but no so much the other one. Not sure why. My dog does not like the taste, so I have to put in food before he will take it. 08/15/2013
Rated 5 out of 5by Works for both of my dogsBoth of my dogs have been using Trifexis since we got them and we have never had a single flea. This is even more amazing because we live in the country and have all kinds of wildlife going through our yard. 08/12/2013
Rated 4 out of 5by Trifexis has worked for usThe only problem we have had with this product is that my one picky dog will not eat it willingly. But we coat it in peanut butter and then all is well. My dogs have both been taking Trifexis for many months and it appears to be effective. 08/07/2013
Rated 5 out of 5by Trifixes really works.I was giving my 4 month old Multees the topic medication that you put in the back of the neck. I thought she was safe from tick and fleas. Boy was I wrong. One day after shower her, I saw lot of fleas on her and panicked as Im sure most of you will. Trifexes was recommended through a friend of mine who had a dog and recommended me to use it. After much research, I asked my vet if its ok to use it. Make the long story short, after first application it worked wonders. No more fleas, ticks or nothing. My dog is healthy and I believe this product really works. One pill a month orally and thats it. You dont have to worry about any ticks or nothing. Man Im so glad I found Trifexes Its a little expensive, but hey I dont care, as long as my puppy is healthy, thats all i care about. 08/07/2013
Rated 5 out of 5by Great preventative medSuch an easy product to use. Not only to prevent worms but bonus flea protection. 08/06/2013
Rated 5 out of 5by This product works great for sensitive dogs...I have a pug..This product works great for sensitive dogs...I have 2 pugs and have not had any problems... 07/23/2013
Rated 5 out of 5by Great ProductI love this product for my puppy. I hated to put something on her skin. I always felt that was harsh. I have never seen anything on her. It even killed the one tick that was one her. 07/22/2013
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