my 5 yr old cat was dx with cryptococcus 4 months ago. We have been giving her Intraconozol-100mg for 3 months now (we got the rx in mexico). Her nose has gotten bigger and she is unable to breath through her nose. Should we try another regime of intraconozol, go to another med or euthanize her. She isn't in any obiouvs pain at this point. There doens't seem to be any CNS involvment.
You can try another antifungal such as Ketoconazole. Talk to your vet about it. Itraconazole is said to more effective but you may want to give another antifungal a chance before you consider euthanasia. Another choice you have is the use of Flucytosine (antifungal) in conjunction with amphotericin B. Good luck, vetcare