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May 22, 2013
Lysodren is a cytotoxic drug used in veterinary medication to treat Cushing’s disease and the related symptoms in dogs. The medication is strong enough to deactivate the cells in a particular area of the adrenal gland, thus reducing the functionality of that particular part of the gland. Therapeutic effects that the medicine displays are attached to Mitotane, the active component present, which works by holding back the adrenal gland functions. This is done by limiting the amount of cortisol being produced in the body. Lysodren is a prescription drug and comes in scores tablet.
Do not use the drug on animals that are hypersensitive to mitotane, which is the active ingredient present in the medicine. The medication should not be tried in pregnant as well as nursing animals. Mitotane has a tendency to interact when used with insulin or spironolactone, and in certain other combination of medicines. It would be wise to inform the veterinarian on the medication that the pet is currently receiving. Personal protection is also important in dealing with the medication, as mitotane is cytotoxic to humans. If in case the drug comes in contact with the skin it has to be washed off immediately. Instances of medication overdose could be fatal if not attended to.
The medication has side effects in animals that might lead to Addison’s disease or its symptoms such as decreased appetite, vomiting and diarrhea, lethargy, weakness etc. Observe the symptoms and in the event of severe reactions to the medicine, supplement with glucocorticoids like prednisone.
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