Clomipramine is not authorized to be used in breeding dogs. Attention should be paid to breeding dogs suffering from cardiovascular dysfunction, epilepsy, narrow angle glaucoma, reduced gastrointestinal motility or urinary retention. Clomipramine should be prescribed with extreme care, only after making a true assessment of the benefit and the risks associated with the medication. Clomipramine is not advisable when consumed in combination with monoamine oxidase inhibitors. Never use Clomipramine or any other tricyclic antidepressants in animals that are allergic to it. Do not use Clomipramine in pregnant, nursing or breeding females, or with other central nervous system (CNS) depressants such as barbiturates. Inform the veterinarian about what other medications the pet is taking.