Injections should not be administered in the same spot every day, as this could cause scarring, which will dampen the bodies ability to absorb the medication. Use with anabolic steroids, adrenergic blockers, MAOIs, aspirin (or other salicylates), phenylbutazone, or tetracycline might increase the effects of Lantus, and should be monitored, while DOBUTamine, EPINEPHrine, furosemide, thiazide, progesterone, glucocorticoids, and estrogen, may decrease the effects. Taking with burdock (a plant with diuretic and blood purifying properties) may have a hypoglycemic effect, and the dosage of insulin may need to be adjusted accordingly. Pets taking digoxin should have their potassium levels monitored.