No insulin should be injected into the same location every day, as this could result in scar tissue, which will affect absorption. Taking Humulin N with anabolic steroids, beta adrenergic blockers, MAOIs, aspirin, phenylbutazone, tetracycline can cause potentiation. The effects of Humulin N may decrease when taken with estrogen agents, glucocorticoids, progestin, thiazide diuretic, dobutamine, epinephrine, or furosemide. Burdock root may cause hypoglycemic effects and you may need to adjust dosages if taking with insulin. Thyroid hormones may cause an initial increase in blood sugar.