Frontline Spray
Frontline Spray
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At a Glance
Fipronil disrupts an insectโ€™s central nervous system, motor skills, and behavior
Kills on contact ticks, chewing lice, mites, and every stage of the flea life cycle
Fast-acting, lost-lasting waterproof treatment for dogs, puppies, cats, and kittens
Monthly spray and mist of the petโ€™s hair and body

Frontline Spray

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At a Glance
Fipronil disrupts an insectโ€™s central nervous system, motor skills, and behavior
Kills on contact ticks, chewing lice, mites, and every stage of the flea life cycle
Fast-acting, lost-lasting waterproof treatment for dogs, puppies, cats, and kittens
Monthly spray and mist of the petโ€™s hair and body

Ultimate Guide to Frontline Spray

Meet the Monthly Mist Master of Pest Control: Frontline Spray!

Frontline Spray is a pest control dog and cat medication that effectively protects your pet from fleas, ticks, mites, and chewing lice. Every 30 days, wet your cat or dog with Frontline's Spray to use a long-lasting treatment that acts fast to keep away these tiny parasites and ensures that your pets are in the most comfortable condition.

How does Frontline Spray work?

Frontline Spray is a medication with one powerful active ingredient - Fipronil - that is an effective drug against adult ticks, chewing lice, mites, and fleas at every step of the flea's life cycle. Frontline Spray kills the tiny parasites on contact by storing itself in the oil glands in your pet's skin and hair follicles continuously for the next 30 days.

Fipronil (0.29% is how much Fipronil in Frontline Spray) is a phenylpyrazole insecticide that disrupts the insect's central nervous system by blocking the GABA-gated chloride channel that regulates cellular excitability and glutamate-gated chloride (GluCl) channels that controls movement, feeding, and behavior.

Through this process, Fipronil eliminates a broad-spectrum variety of insects. This drug blocks the major neurotransmitter of the insect's cell chemistry that causes fatal contamination to the insect's nerves and muscles. As a GABA(A) antagonist, Fipronil causes hyper excitement to the contaminated insect's nerves and muscles.

How is Frontline Spray administered?

Frontline Spray is administered once a month topically and protects your pet for the next 30 days. Spray the mist all over the back, sides, stomach, legs, shoulders, and neck until your pet's hair is completely and uniformly dampened. Pets may swim or be bathed 24 hours after Frontline Spray is applied (and fully dried).

Wear latex gloves to keep the spray from contact with your and your pet's skin, eyes, and mouth. If you have Frontline on your hands, wash them thoroughly with soap and water.

Available amounts are 8.5 fl oz (250 ml) and 17 fl oz (500 ml). How much Frontline Spray per pound is approximately one or two pumps per pound of your pet's body weight will be required. Reapply Frontline Spray after 30 days.

What are the potential side effects of which you should be aware?

Pet sensitivities that respond to pesticide products are rare. Any side effects must be reported to your veterinarian. Other Frontline products adverse reactions in dogs have been signs of skin afflictions, and gastrointestinal reactions such as vomiting and diarrhea.

Frequently Asked Questions
  1. How long does it take for Frontline Spray to work?

    One spray session will rid your pet of fleas within 18 hours, ticks within 48 hours, and lasts for 30 days. The medicine kills adult fleas, prevents reproduction, and stops existing flea infestations. The medicine kills all varieties of ticks and disrupts the tick's life cycle (i.e., larva, nymph, and adult).

  2. Is Frontline Spray for puppies and Frontline Spray for kittens?

    Frontline Spray can be used on puppies and kittens that are at least 8 weeks of age.

  3. How long does Frontline Spray take to dry?

    Frontline Spray dries within 24 to 48 hours. After this, your pet can swim or be bathed for a monthly waterproof treatment.

  4. What do Frontline Spray reviews say?

    Frontline Spray reviews rate 4.5+ out of 5 stars. Most reviewers say that Frontline Spray is an effective problem solver for their tiny parasite control problem for their pets.

  5. What is the difference between the Frontline Spray vs. spot-on Frontline treatment?

    The main difference between Frontline Spray and Frontline Plus For Dogs is the way they are applied - mist spray versus a spot-on treatment. The former can be also used on cats and kittens. The latter has one other active ingredient, the insecticide (S)-methoprene. Both are easy-to-use and effective treatments.

  6. What if your cat licks the Frontline Spray?

    If licking occurs shortly after application, a brief period of hyper-salivation may occur due to the taste.

Concluding Thoughts

The most important thing that you should know about Frontline Spray is its power to protect your pets from tiny parasites (i.e., fleas, ticks, chewing lice, and mites) with one spray session monthly.

DISCLAIMER: FDA law restricts Frontline Spray only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if this is a suitable product for your pet and your home.

Does Frontline Flea Spray Work?

One of the most popular pest infestation control methods opted by pet owners and veterinarians across the world is the Frontline Flea Spray for dogs and cats. The spray contains Fipronil as a major ingredient. It helps your pet by killing the pre-existing infestation. It also aids in stopping the growth or formation of new colonies. It kills chewing lice, ticks, and fleas. These harmful pests are generally found among the pets that people keep at their houses. Frontline spray can be applicable for both cats and dogs. A single application of Frontline Flea Spray for cats and dogs protects your pet for at least thirty days. And it is also observed that it may be effective for a period of even ninety days in some cases.

How Do You Use Frontline Spray?

Any medicine or medicated product usage on pets needs the demonstration of extra care and precaution by the pet owners. It is also advisable that if you are unsure of how to use the Frontline Spray, there are broadly two ways you can follow. The first method can be to follow the usage instructions as mentioned on the product packaging, while the second can be to pursue the expert opinion of a certified practicing veterinarian. Whichever method you are using for the application of Frontline Flea Spray on your pet, it is vital to adhere to the instructions that you choose to follow. It must be your priority as a responsible pet owner that you must always be cautious. It is also recommended that you must take special care while applying the spray around your petโ€™s head region, especially near the eye, nose, and mouth, and other sensitive areas of the body. To apply the Frontline Flea Spray properly, you must first apply the spray on your hands thoroughly. You should be wearing gloves during this time. In the next step, you can spread them gently and evenly on the sensitive areas. You should put on the product until the hair of your pet becomes completely wet. It is estimated that every one or two pumps of your Frontline Spray can cover a pound of weight of your petโ€™s body.

How Quickly Does Frontline Spray Work?

After the application of Frontline Spray, it completely eliminates most of the parasitic entities within twenty-four-hour of its use. To properly take care of your pet you must regularly apply the spray. This interval can be according to your petโ€™s body size, weight, and kind. For most accurate medication it is advised to contact a reputed licensed veterinarian.

Does Frontline Work Immediately?

A relative comparison of Frontline Flea Spray for cats and dogs with other competitive products in the market ranks its action to be very effective. However, you should give it some time to see the best results. Frontline Spray takes almost eighteen hours to fully cover the body of your pet after the initial application. After twenty-four hours of application, Frontline Flea Spray for cats and dogs will completely get rid of almost all the fleas in your petโ€™s body. Also, a crucial aspect to note is that you can expect complete irradiation of the infestations within forty-eight hours of application.

How Often Can I Use Frontline Spray?

You can administer Frontline Spray to your pet once every month. As Frontline Spray can be applicable for both cats and dogs, you need to know your petโ€™s proper administration schedule and the time interval between each application. For the most optimal solution for your pet, it is recommended that you consult your veterinarian. Frontline Spray remains effective against the parasitic organisms for the entire duration of a month.

Is It Safe to Use Frontline Twice a Month?

To maintain proper frequency, you can apply Frontline Spray once a month. It is established that the Frontline Spray can remain effective for a minimum period of thirty days. Even though no overdose complications or problems have been reported even after five times the normal dosage usage, it is still recommended to not use Frontline Spray more than once a month. Increasing usage of the dosage may show some drastic reactions in the foreseeable future.

Is Frontline Spray Effective?

Frontline Flea Spray for cats and dogs is a parasitic prevention medicament, that takes care of any generally found entities on your petโ€™s outer body. These entities are mainly found to be present on their epidermal layer and the hair follicle. The ingredients in the spray directly affect the parasitic organisms that are present on the outer layer of your petโ€™s body. These organisms are already exposed to the open environment, which makes it extremely easy to permanently terminate them.


The individual sensitivities of your pet can respond to pesticide products such as Frontline flea and tick spray; report to your veterinarian if side effects occur.

Frontline Spray is to be applied once every 30 days throughout flea season; wear latex gloves when administering it, and keep the spray from contact with your skin, or with your or pets eyes and mouth. To apply, ruffle your petโ€™s coat and then spray the mist over the back, sides, stomach, legs, shoulders, and neck until the hair is completely dampened. Spray a gloved hand, and rub the spray over the head and eye area. Wash your hands thoroughly with soap and water after applying Frontline Spray to your pet.

Frontline Spray is best used in conjunction with other long-term Frontline flea control products.

Store at room temperature.

Frontline is manufactured by Merial

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