Diphenhydramine is an antihistamine, also known as the generic form of Benedryl. It is used to treat allergies, insect stings/bites, motion sickness and travel anxiety. The medication is safe for all ages and weights of dogs or cats. It should not be used by dogs or cats that are pregnant or nursing.
Dosage is .5-2mg per pound of your pet; be sure to administer the proper dosage. See directions below and your package instructions for details. Always follow your veterinarian's prescribed dosage if it differs from the standard dosage recommendations.
Diphenhydramine is the Generic Alternative to Benadryl and/or Apoquel.
Diphenhydramine HCL should be used with caution in pets suffering from angle-closure glaucoma, prostatic hypertrophy, bladder neck or pyloroduodenal obstruction, COPD, hyperthyroidism, cardiovascular disease, or hypertension. Should only be used in pregnant patients when the benefits outweigh the risks. Taking diphenhydramine with CNS depressants might cause excessive depression of the central nervous system. MAOI inhibitors might intensify the anticholinergic effects of diphenhydramine. Diphenhydramine might overly enhance the effects of epinephrine, and counteract the anticoagulant effects of heparin or warfarin. Possible side effects of diphenhydramine HCL are CNS depression, dry mouth, urine retention, vomiting, diarrhea, and loss of appetite. The sedative effects of diphenhydramine might lessen over repeated uses. In some cats, a paradoxical CNS excitation might occur.