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Mammary tumors are commonly seen in middle-aged or older female dogs. The risk factors in such cases are due to increased age exposure to ovarian and growth hormones, ovariectomy after 2.5 years of age and obesity at a young age.
Just about most
of these tumors are malignant. A local recurrence and distant spread is,
however, possible following their removal through surgical processes. Prognosis
is affected by the tumor size, type grade and clinical stage wherein there
might occur a spread of disease throughout the body during the time of
diagnosis. While these tumors are rarely fatal, they remain a major health
concern for owners of female dogs.
the Ohio State University are exploring the use of optical coherence tomography
(OCT) in order to help doctors reach important and required
margins during surgical removal of mammary tumors and soft tissue sarcomas
in female dogs.
Optical Coherence Tomography (OCT)
- Have functions similar to an ultrasound.
- Uses light reflected to dig deep instead of
using sound waves as used in ultrasound
- The light reflects from various tissue surfaces
and provides a high-resolution(with regards to the tumor)
cross-sectional image of the tissue structure in the present place and time can
- Helps distinguish between soft tissue sarcoma,
muscle tissue, and fatty tissue
mammary tumor is caught, the use of OCT could provide an accurate and
intra-operative method to determine surgical margins.
to AKC CHF Grant 2204-T: employing advanced
imaging techniques, it has become comparatively easier to calculate tumor signs
for mammary cancer in dogs and Soft Tissue Sarcoma.
have already taken the first step toward reaching their accomplishment.
medicine is on the path to achieve high grounds marking treatment targets
for mammary tumors in dogs. A research at the University of Pennsylvania has
found properties of collagen in the tumor microenvironment for dogs which
identity with patient survival time.
CHF Grant 2489: Tumor-permissive Collagen
Signatures in Mammary Gland Tumors for dogs:
the form of Prognostic Markers, as well as Targeted Therapies for the improved
outcome, should help researchers study the naturally occurring mammary tumors
in dogs adopted or placed in permanent foster care, taking up a program called
‘Penn Vet Shelter Canine Mammary Tumor Program.'
This is known to provide a full lifelong mammary tumor care for dogs enrolled
here and also gives data related to the research a measure through the clinical
research also shall explore added collagen traits that foretell outcomes and
scrutinize their affect tumor behavior. They hope to develop modes that should
avoid the formation of tumor-friendly
microenvironments in the mammary glands of dogs.
A well-known treatment for mammary tumors in dogs would be a surgical removal is. However, this situation is age sensitive to a dog. If the dog is of much age, it is at a much higher risk due to after surgery conditions for a dog as immense care is to be given to the dog in order for it to heal and regain its strength.
studies are capable of providing a tool which is known to allow doctors to
completely remove the tumor tissue in one go.