At a Glance
Kills fleas, prevents heartworm, and treats and controls intestinal parasites
Once monthly beef flavored chewable tablet
No isolation from other pets necessary
An alternative to Trifexis is Sentinel
Our regular price:
This item is on sale!
Spinosad, Milbemycin oxime
Side Effects and Warnings
Adverse reactions include vomiting, itching, ear redness, skin redness and inflammation, loss of appetite, diarrhea, and lethargy. Use with caution in dogs with epilepsy. Puppies less than 14 weeks old may excessively vomit. Consult your veterinarian in regard to pregnant or lactating dogs. If dog experiences any listed effects, immediately contact your veterinarian. Not for breeds of collie.
Do not use ivermectin in addition to Trifexis. Consult your veterinarian regarding the addition of any other medication, supplement, or vitamins.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
Elanco Animal Health
5-10 lbs., 6 pack
10.1-20 lbs., 6 pack
20.1-40 lbs., 6 pack
40.1-60 lbs., 6 pack
60.1-120 lbs., 6 pack
Store at room temperature.
Dog must be tested by a veterinarian, and rid of worms, prior to taking Trifexis. Administer Trifexis orally according to prescribed dosage, based on weight.
Other Customers Also Bought for their Pet
- Small and easy to administer
- Safe to crush and mix with food
- 100% effective against both types of tapeworm
- FDA approved
- 100% Natural Salmon Oil
- Excellent Source of Omega Fatty Acids
- Great for Skin & Coat, Joint, Digestive & Overall Health
- Tasty treat and toy in one
- Fully digestible, packed with low-fat protein
- Good for dog's dental health
Rated 4.3 out of 5 by 78
Rated 5 out of 5 by dlyo Works great.
It's nice to have a 3-in-1, so only one rx needed. Works much better against fleas than any topical we tried. My dog has been itch free since we started using Trifexis. Only problem is she doesn't like the taste, we have to crush it and mix with something she likes.
July 14, 2014
Rated 5 out of 5 by Ralph Completely satisfied with the product
My dog hasn't had any side-effects to this medicine or any of the infestations it attempts to prevent. Based off my observations and annual stools sampled by the vet.
May 31, 2014
Rated 5 out of 5 by Teddy Trifexis
Our Dog Ted has had two monthly doses. We live in Florida. I have noticed a lot less itching, so I think Its working like It should. We hope It contines to work. Thanks Janice Mc Mullen.......Tavares Florida
May 26, 2014
Rated 5 out of 5 by rmolly Keeps my dog healthy without the worry.
We have a Cairn Terrier. Our Vet recommended this product and although it is a little pricy; it does keep her healthy without my worrying about fleas, tics, heartworm, etc. She takes it willingly.
May 22, 2014
Rated 5 out of 5 by Gypsymi The Best for flea and internal parasites
This product would be perfect if it contained heart worm prevention as well. Oh . . .and if someone else gave the pill to my 85 lbs American Bulldog . . .what a fight!!! The other 3 dogs were easy by comparison; a chow mix, a brown dog???, and a yorkie/maltese mix
May 20, 2014
Rated 4 out of 5 by funigan I like a product that kills multiple pests
This pill is definitely NOT something that is palatable. It may be "beef flavored" but even disguised inside a cheese cube my Lhasa Apso can smell the distinctive unpleasant aroma of this medicine, and I have to pry his jaws open to get the cheese cube in and hold his jaws shut to make sure he swallows it!
May 13, 2014
Rated 5 out of 5 by oberstein1 TRY Trifexis
If you have not yet tried this product you are missing out. This is our second season with this and have seen no fleas, ticks or worms. It may seem expensive but consider the cost of the 3 products it replaces and it is a bargain. No more oily fur and worrying about not petting your dog after applying products like frontline.
May 12, 2014
Rated 5 out of 5 by Salesgunner Simple yet very good
One pill a month to treat everything and cheaper then buying at the vet's office!
May 11, 2014
Elanco Animal Health
Flea & Tick
Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.
In stock! Order now!
As a Treatment Plan member, enjoy the following benefits and typically save $300-$400 per year
- All of your pet prescriptions at our cost
- Save 25% every time you go to the vet (through PetAssure)
- Convenient pickup at over 60,000 local pharmacies, including CVS, Target, Walgreens, and Walmart
- 20% off everything at PetCareRx.com
- $50 off your first dog sitter booking with Rover.com
- Guaranteed savings in your first year as a member
- And much more...
All this for only $9.99/month
Would you like to upgrade?
Add at Regular Price