At a Glance
Trifexis kills fleas, prevents heartworm, and treats and controls intestinal parasites
Trifexis is a once monthly beef flavored chewable tablet
No isolation from other pets necessary when using Trifexis
An alternative to Trifexis is Sentinel
Our regular price:
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Spinosad, Milbemycin oxime
Side Effects and Warnings
Adverse reactions to Trifexis include vomiting, itching, ear redness, skin redness and inflammation, loss of appetite, diarrhea, and lethargy. Use Trifexis with caution in dogs with epilepsy. Puppies less than 14 weeks old may excessively vomit. Consult your veterinarian in regard to pregnant or lactating dogs before giving them Trifexis. If your dog experiences any listed effects, contact your veterinarian immediately. Trifexis is not meant for any Collie breed dogs.
Do not use ivermectin in addition to Trifexis. Consult your veterinarian regarding the addition of any other medication, supplement, or vitamins.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
Elanco Animal Health
5-10 lbs., 6 pack
10.1-20 lbs., 6 pack
20.1-40 lbs., 6 pack
40.1-60 lbs., 6 pack
60.1-120 lbs., 6 pack
Store Trifexis at room temperature.
Dog must be tested by a veterinarian, and rid of worms, prior to taking Trifexis. Administer Trifexis orally according to prescribed dosage, based on weight.
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Rated 4.4 out of 5 by 97
Rated 4 out of 5 by SusieQ73 Pros and Cons
We switched from Frontline about 1/2 a year ago. For some reason we were still occasionally dealing with a flea problem. My dog is allergic to fleas...one flea and she is a mass of scratching and fur loss and ends up looking like a lion! Our vet recommended Trifexys. I love that fleas and heartworm etc can be taken care of with one application BUT my dog does not like this pill and we go through trauma each month getting it down her throat. She is a master of holding on to it! But we manage in the end and I will continue to purchase.
June 13, 2015
Rated 5 out of 5 by 2labs It works!
We've tried all the other flea medications and trifexis is the only one that works for our dogs. Our male lab will eat anything and he has no problem taking it with a little peanut butter. Our female however will not take it, we have to put it in her throat and hold her mouth shut until she swallows it. She also throws up if we give it with food, on an empty stomach it is fine.
May 27, 2015
Rated 5 out of 5 by Melodie Excellent Product for Fleas & Heartwork Prevention
This product was the lifesaver for our GSD. We tried other products, but this one did the trick! Easy to use, no mess and also prevents heartworm. Great product!!
February 21, 2015
Rated 5 out of 5 by Adamstuart Trifexis
I have an 8 pound, 9 year old dog and she has been taking this medication for a few years without any problems.
I find it less messy than the liquid kind of flea protection
I just put it in her food at nigt and she eats it, no problem!
November 23, 2014
Rated 5 out of 5 by Lynn3 So easy to administer.
Dogs think it's a treat. No oily residue or smell like the topical applications.
November 18, 2014
Rated 5 out of 5 by Nati Very efficient product
I've used several different flea and heartworm products over the years and I find that Trifexis really does the job. It is not cheap and my dogs don't like it ( I have to shove it in their mouth which is no fun).
October 23, 2014
Rated 5 out of 5 by Spansl Great price and service
Unfortunately Banfield will not allow us to send our prescription from them to PetcareRX to get the better pricing on Trifexis :( We may have to find another vet.
October 18, 2014
Rated 5 out of 5 by Maddie Pricey
This is a pricey drug but effective my dog still itches but its not from fleas guess it's an allergy
October 17, 2014
Elanco Animal Health
Flea & Tick
Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.
In stock! Order now!
based on 97
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