At a Glance
Trifexis kills fleas, prevents heartworm, and treats and controls intestinal parasites
Trifexis is a once monthly beef flavored chewable tablet
No isolation from other pets necessary when using Trifexis
An alternative to Trifexis is Sentinel
Our regular price:
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Spinosad, Milbemycin oxime
Side Effects and Warnings
Adverse reactions to Trifexis include vomiting, itching, ear redness, skin redness and inflammation, loss of appetite, diarrhea, and lethargy. Use Trifexis with caution in dogs with epilepsy. Puppies less than 14 weeks old may excessively vomit. Consult your veterinarian in regard to pregnant or lactating dogs before giving them Trifexis. If your dog experiences any listed effects, contact your veterinarian immediately. Trifexis is not meant for any Collie breed dogs.
Do not use ivermectin in addition to Trifexis. Consult your veterinarian regarding the addition of any other medication, supplement, or vitamins.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
Elanco Animal Health
5-10 lbs., 6 pack
10.1-20 lbs., 6 pack
20.1-40 lbs., 6 pack
40.1-60 lbs., 6 pack
60.1-120 lbs., 6 pack
Store Trifexis at room temperature.
Dog must be tested by a veterinarian, and rid of worms, prior to taking Trifexis. Administer Trifexis orally according to prescribed dosage, based on weight.
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Rated 4.4 out of 5 by 103
Rated 5 out of 5 by GingersMom Trifexis is effective and easy to administer
Have used this product with both my dogs and never had an issue with fleas while simultaneously treating them with heartworm prevention. The website saves a little money and is easy to use. Your vet may not be efficient allowing for the prescription.
August 25, 2015
Rated 5 out of 5 by Trisa1 Good product for great price
I've been paying way too much at my vets office for this product. This is effective way to prevent ticks, fleas and worms. Highly recommend.
August 23, 2015
Rated 4 out of 5 by Shelly0000 Product is simple to use.
I won't go back to the mess of applications (of sorts) again.
I Hide it in some peanut butter and once in a while I can get them to just take the pill.
August 3, 2015
Rated 5 out of 5 by Pet1 Trifexis makes my dog nausaus for a couple of days after she takes it. PLEASE, do not deliver her meds in a hard box anymore because I could not get
the box out of the US Postal Service receptical and had to wait 3 days to get it.....not good in this heat. PLEASE do not deliver it again in a hard box.
July 22, 2015
Rated 4 out of 5 by Dav111 Good product, fair price, but slow.
I ordered a medication and immediately mailed in the vet's prescription. Waited about 2 weeks to receive the meds. The price (especially with the PetPlus discount) was worth the wait. All in all, with advance planning, PetCare Rx is preferable to the steep mark-up my vet would have charged. I appreciated the notifications via e-mail and phone on the progress of my order.
July 21, 2015
Rated 5 out of 5 by Derfnnan Best price
Trifexis is easy to administer and the results are unbeatable.
July 17, 2015
Rated 4 out of 5 by SusieQ73 Pros and Cons
We switched from Frontline about 1/2 a year ago. For some reason we were still occasionally dealing with a flea problem. My dog is allergic to fleas...one flea and she is a mass of scratching and fur loss and ends up looking like a lion! Our vet recommended Trifexys. I love that fleas and heartworm etc can be taken care of with one application BUT my dog does not like this pill and we go through trauma each month getting it down her throat. She is a master of holding on to it! But we manage in the end and I will continue to purchase.
June 13, 2015
Rated 5 out of 5 by 2labs It works!
We've tried all the other flea medications and trifexis is the only one that works for our dogs. Our male lab will eat anything and he has no problem taking it with a little peanut butter. Our female however will not take it, we have to put it in her throat and hold her mouth shut until she swallows it. She also throws up if we give it with food, on an empty stomach it is fine.
May 27, 2015
Elanco Animal Health
Flea & Tick
Trifexis is a powerful and effective means of preventing heartworm disease, as well as protect against fleas and a number of other worms and parasites.
In stock! Order now!
based on 103
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