At a Glance
Manages urinary incontinence in dogs and cats
Helps to reduce accidents
Available in liver flavored chewable tablets
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Proin is a prescription, liver-flavored chewable tablet, intended to manage urinary incontinence in dogs and cats, by constricting and strengthening the urinary sphincter. Proin is a supplemental adrenergic agent, which means it mimics adrenaline or epinephrine, which are the hormones needed to trigger vasoconstriction, the constriction of blood vessels.
Proin also maintains balanced phenylpropanolamine levels, helping to prevent the negative side effects associated with high levels, including heightened blood pressure, and hyperexciteability. Proin is a classified controlled substance in Arkansas, Iowa, Louisiana and Oregon.
Side Effects and Warnings
Keep out of reach of children.
Do not give with ephedrine or epinephrine, or within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Proin may cause restlessness and hyperactivity, pale gums, difficulty urinating, irritability, hypertension, and decreased appetite. Hypertension risk increases if Proin is given concurrently with non-steroidal anti-inflammatory drugs (NSAIDs), or with reserpine, tricyclic antidepressants, amitraz (the active ingredient of the Preventic tick control collar and canine Promeris, a flea control product), or ganglionic blocking agents. Conditions such as glaucoma, prostatic hypertrophy, hypertension, hyperthyroidism, diabetes mellitus, and cardiovascular disorders, may worsen.
Side effects may worsen if used in conjunction with other sympathomimetic drugs such as ephedrine or epinephrine. Notify your veterinarian of any medications, treatments or vitamins your dog is taking, prior to administering Proin.
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.
This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
25mg per chewable tablet
50mg per chewable tablet
75mg per chewable tablet
Store at room temperature away from moisture and heat.
Administer Proin chewable tablets, to the exact specifications of your veterinarian, and with food.
||Tablets: The usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Drops: 0.4-0.8mg/pound every 12 hours.
Rated 4.8 out of 5 by 41
Rated 5 out of 5 by WestieMom Keeping my dog healthy
My Westie, Blanche, is now 9 years old and has been on Proin the entire time we've had her (since she was a pup). It has helped us avoid 99% of accidents and shows no adverse side effects.
August 13, 2014
Rated 5 out of 5 by Joshua39 Does the job as advertised.
Great product. Our dog is now comfortable with her bladder.
August 3, 2014
Rated 5 out of 5 by lorraine56 Very effective
This product has done very well with my dog. She has had no accidents so her response with this medication has been excellent.
July 28, 2014
Rated 5 out of 5 by Josie Effective Product
Our retriever has been on this product since she was a puppy, now 13 yrs, and it has helped in bladder control.
M in San Mateo, CA
July 19, 2014
Rated 5 out of 5
by vicmaster couldn't live without it
my dog has been on proin for six years now because of incontinence. i couldn't have a 113 lb dog in my home without this product. it worked perfectly for 5 years and now i've had to add hormones. but that's OK.
June 26, 2014
Rated 5 out of 5 by Judy99 All around, very good results.
Proin is doing an excellent job controlling my elderly boxer girl's incontinence. She tolerates the Proin very well and no longer wakes up in the morning mortified at having wet her bed.
June 23, 2014
Rated 5 out of 5 by DozerOwner Great for dog urine control
We have a 180+ English Mastiff Male who after surgery could not express his urine. With the Proin, he can control expressing it and is a happier dog for it.
June 2, 2014
Rated 5 out of 5 by AprilC Works excellent!
I have a Husky that involuntarily leaks when she's asleep. This product and Bladder Strength keeps her completely dry! I definitely would recommend this product.
April 5, 2014
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based on 41
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