Generic Name
Chloramphenicol Tablets
Indications/Uses
VicetonTabs may be used in the treatment of dogs under conditions such as bacterial pulmonary infections, infections of the urinary tract, enteritis, infections associated with canine distemper, etc. This preparation will be effective only in the treatment of infections caused by susceptible microorganisms such as Staphylococcus aureus, Streptococcus pyogenes, Brucella bronchiseptica, Escherichia coli, Proteus vulgaris, Corynebacterium renale, Streptococcus spp., hemolytic Staphylococcus, Proteus spp., Salmonella spp., Pseudomonas spp, Brucella bronchiseptica, P. aeruginosa, Shigella spp. and Neisseria catarrhalis.If necessary, additional therapy should be used with the chloramphenicol therapy. By following the suggested dosage pattern most of the susceptible infectious disease organisms should respond to chloramphenicol therapy in three to five days. Diagnosis and therapy should be reassessed if the infection is not responding to the chloramphenicol therapy in three to five days. Also, consider a change of therapy.
Precautions
This antibiotic contains a chemical structure (nitrobenzene group) typical to a group of drugs recognized to cause depress hematopoietic activity of the bone marrow. In vitro-tissue culture studies that have been done using canine bone marrow cells have shown that very high concentrations of chloramphenicol reduces both uptake of iron by the nucleated red cells and incorporation of iron into heme. Because of the prolonged recovery time, avoid administering products containing chloramphenicol with or two hours prior to the induction of general anesthesia with pentobarbital. Dogs maintained for breeding purposes should not be treated with chloramphenicol products. Studies on experimental animals treated with chloramphenicol have shown that animals, especially females, experience significant disorders in morphology as well as in function of the gonads.
Side Effects
This antibiotic contains a chemical structure (nitrobenzene group) typical to a group of drugs recognized to cause depress hematopoietic activity of the bone marrow. In vitro-tissue culture studies that have been done using canine bone marrow cells have shown that very high concentrations of chloramphenicol reduces both uptake of iron by the nucleated red cells and incorporation of iron into heme. Because of the prolonged recovery time, avoid administering products containing chloramphenicol with or two hours prior to the induction of general anesthesia with pentobarbital. Dogs maintained for breeding purposes should not be treated with chloramphenicol products. Studies on experimental animals treated with chloramphenicol have shown that animals, especially females, experience significant disorders in morphology as well as in function of the gonads.