Proin (Phenylpropanolamine)
Generic Name
Phenylpropanolamine
Indications/Uses
Proin is an adrenergic agent effective in the treatment of urinary incontinence in animals. This extra-label medication is fit to be used only in dogs. Proin works by increasing the sphincter tone of urethra, which tightens the bladder sphincter muscles thereby preventing urine leakage.
Precautions
Avoid using proin in animals with a history of allergy to the ingredients of this drug. Animals suffering from conditions of glaucoma, enlarged prostate, hyperthyroidism, diabetes, heart problems or high blood pressure should be kept away from proin. Abstain from using Proin in pregnant and breeding animals as it can cause harmful effects in them.
Side Effects
The most common side effects noted while administering proin are restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Restlessness, weakness, pale gums, seizures, or difficulty in urinating are also reported as occasional side effects while being treated with phenylpropanolamine.
Dosage Information
Proin is available in 25 mg, 50 mg and 75 mg chewable tablets. Dosage of proin generally depends on the body weight of the animal. However, a dose of 12.5 mg to 50 mg can be administered three times daily, depending on weight. The usual dose of Proin in dogs is 0.4-0.8 mg/pound every 12 hours. Over dosage can bring about symptoms of high blood pressure, increased heart rate, seizures or coma. Do not increase or reduce the dosage without veterinary prescription.
Brand Names
Proin (PRN Pharmacal), Propaline, Cystolamine