Generic Name of
Firocoxib is used for treating pain and inflammation normally associated with osteoarthritis in dogs. Firocoxib belongs to the group of non-steroidal, anti-inflammatory drugs (NSAID) belonging to the coxib class, which provides faster pain relief and improved mobility. Firocoxib has also analgesic properties, and relieves pain and swelling in dogs by hindering the production of the body chemicals called prostaglandins. Prostaglandins are influenced by the cellular enzyme cyclooxygenase (COX), which are of two types - COX1 & COX2. Most NSAIDs act upon both these types, though COX2 is found to be mainly responsible for producing pain and inflammation associated with tissue damage.
Precautions when using
Firocoxib can cause renal, gastrointestinal, and hepatic toxicity, so dogs with corresponding conditions should be wary of potential side effects. Firocoxib cannot be accurately dosed for dogs under 12.5 pounds, and pet parents should exercise caution giving very small dogs this drug. This medication can interact poorly with other NSAIDs, so if further pain medication is necessary, your dog may need a non-NSAID analgesiac. The research still has not been done to see if Firocoxib has a detrimental affect on pregnant, lactating, and breeding dogs. Use caution.
Side Effects of
Side effects of Firocoxib may include a surge or fall in appetite, nausea, diarrhea, dark stools, seizure, aggression, etc. Symptoms like sudden weight loss, jaundice, scabs or itchy skin are also noticed in some animals.
Dogs should take 2.27 mg/lb (5.0 mg/kg) of body weight daily for the purpose of treating osteoarthritis. If taking firocoxib to relieve postoperative pain and inflammation, the same dose can be taken for three days following surgery. Additionally, dogs can be treated with firocoxib two hours prior to surgery to help with pain and inflammation.
Brand Names of
Deltasone (Pharmacia), Sterapred (Merz)