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Clemastine fumarate


Generic Name of Clemastine fumarate: Clemastine fumarate

Indications for Clemastine fumarate

Clemastine fumarate belongs to the ethanolamine group of antihistamines, which are commonly used for the treatment of allergy. It is a H1 Blocker that prevents the action of histamine on body tissues thereby bringing relief to itching and allergic conditions. Clemastine fumarate is found to be very effective for pruritus in dogs and could be used along with other anti-inflammatory drugs to enhance its efficacy. Clemastine fumarate is probably the most reliable antihistamines for the treatment of itchy skins in dogs. This drug is registered for exclusive use in humans, however many vets use Clemastine fumarate as an extra label medicine.

Precautions when using Clemastine fumarate

Clemastine fumarate should not be used in animals that are hypersensitive to it. Special care is required while administering this medication in animals with known prostate and bladder conditions, heart ailments and glaucoma. Extreme caution is needed while using this medicine on animals on sedatives or tranquilizers. Clemastine fumarate is thought to be safe for use in pregnant animals; however its traces will be present in mothers’ milk, so be cautious while using this medication in nursing pets. Overdose of this medication might result in dry mouth, blurred vision, rapid heart rate, urinary retention, fever and low pressure, which require urgent medical intervention.

Side Effects of Clemastine fumarate

Sedation, paradoxical hyperactivity and dryness of the mouth are some of the common side effects of Clemastine fumarate. In cats, diarrhea is most common; however, persistent diarrhea requires attention. In some cases, animals might as well show symptoms like rapid heartbeat or difficulty in urinating, which call for immediate medical help.

Dosage for Clemastine fumarate

It is available in unflavored tablet form, which should be given orally once in every 12 hour. In dogs, the dosage of Clemastine fumarate is at 0.025 – 0.05 mg per pound (0.5 – 0.2 mg/kg) and in cats, clemastine is dosed at 0.67mg per cat. For conditions like atopic dermatitis, a higher dose at 0.07 mg per pound is recommended.

Brand Names of Clemastine fumarate

Antihist-I, Dayhist, Tavist (All human formulations)